Method for isolating DNA

The present invention provides a method for the isolation of nucleic acid from microbial cells in an environmental sample. The method includes preparing a suspension of the environmental sample, lysing the suspended sample with a buffered solution, adding sodium dodecylsufate solution to the lysed s...

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Main Authors: Hassan, Mohd Ali, Tabatabaei, Meisam, Zakaria @ Mamat, Mohd Rafein, Abdul Rahim, Raha, Wright, Andre-Denis G., Shirai, Yoshihito, Abdullah, Norhani, Shamsara, Mehdi, Sakai, Kenji
Format: Patent
Published: 2008
Online Access:http://psasir.upm.edu.my/id/eprint/26962/
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author Hassan, Mohd Ali
Tabatabaei, Meisam
Zakaria @ Mamat, Mohd Rafein
Abdul Rahim, Raha
Wright, Andre-Denis G.
Shirai, Yoshihito
Abdullah, Norhani
Shamsara, Mehdi
Sakai, Kenji
author_facet Hassan, Mohd Ali
Tabatabaei, Meisam
Zakaria @ Mamat, Mohd Rafein
Abdul Rahim, Raha
Wright, Andre-Denis G.
Shirai, Yoshihito
Abdullah, Norhani
Shamsara, Mehdi
Sakai, Kenji
author_sort Hassan, Mohd Ali
building UPM Institutional Repository
collection Online Access
description The present invention provides a method for the isolation of nucleic acid from microbial cells in an environmental sample. The method includes preparing a suspension of the environmental sample, lysing the suspended sample with a buffered solution, adding sodium dodecylsufate solution to the lysed suspended sample, carrying out solvent extraction and separation to obtain an aqueous phase, reacting the aqueous phase with solvents to generate an insoluble precipitate containing nucleic acid, and isolating the nucleic acid therefrom, thereby releasing high molecular weight nucleic acid pellets from the cells.
first_indexed 2025-11-15T08:51:15Z
format Patent
id upm-26962
institution Universiti Putra Malaysia
institution_category Local University
last_indexed 2025-11-15T08:51:15Z
publishDate 2008
recordtype eprints
repository_type Digital Repository
spelling upm-269622016-09-08T02:37:25Z http://psasir.upm.edu.my/id/eprint/26962/ Method for isolating DNA Hassan, Mohd Ali Tabatabaei, Meisam Zakaria @ Mamat, Mohd Rafein Abdul Rahim, Raha Wright, Andre-Denis G. Shirai, Yoshihito Abdullah, Norhani Shamsara, Mehdi Sakai, Kenji The present invention provides a method for the isolation of nucleic acid from microbial cells in an environmental sample. The method includes preparing a suspension of the environmental sample, lysing the suspended sample with a buffered solution, adding sodium dodecylsufate solution to the lysed suspended sample, carrying out solvent extraction and separation to obtain an aqueous phase, reacting the aqueous phase with solvents to generate an insoluble precipitate containing nucleic acid, and isolating the nucleic acid therefrom, thereby releasing high molecular weight nucleic acid pellets from the cells. 2008-07-30 Patent NonPeerReviewed Mohd Ali Hassan (2008) Method for isolating DNA. UNSPECIFIED.
spellingShingle Hassan, Mohd Ali
Tabatabaei, Meisam
Zakaria @ Mamat, Mohd Rafein
Abdul Rahim, Raha
Wright, Andre-Denis G.
Shirai, Yoshihito
Abdullah, Norhani
Shamsara, Mehdi
Sakai, Kenji
Method for isolating DNA
title Method for isolating DNA
title_full Method for isolating DNA
title_fullStr Method for isolating DNA
title_full_unstemmed Method for isolating DNA
title_short Method for isolating DNA
title_sort method for isolating dna
url http://psasir.upm.edu.my/id/eprint/26962/