The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1
The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell...
| Main Authors: | , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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2012
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| Online Access: | http://psasir.upm.edu.my/id/eprint/26797/ http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf |
| _version_ | 1848845674707156992 |
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| author | Cornelius, Cecilia Evelyn Mohd Noor, Mohd Hezmee |
| author_facet | Cornelius, Cecilia Evelyn Mohd Noor, Mohd Hezmee |
| author_sort | Cornelius, Cecilia Evelyn |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell proliferation assay for these cells showed the absorbance of treated cells was significantly (p<0.05) higher than the control. The live-dead assay showed that the viability of the treated cells was significantly (p<0.05) lower than the control for EMT6 cells while there was no significant difference for the 4T1 cells, however the viability of the treated cells was lower than the control. This study provides preliminary evidence that meloxicam may inhibit growth and viability of mouse mammary tumour cell lines EMT6 and 4T1. |
| first_indexed | 2025-11-15T08:50:34Z |
| format | Conference or Workshop Item |
| id | upm-26797 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:50:34Z |
| publishDate | 2012 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-267972016-08-10T08:09:42Z http://psasir.upm.edu.my/id/eprint/26797/ The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 Cornelius, Cecilia Evelyn Mohd Noor, Mohd Hezmee The in vitro growth of mouse mammary tumour cell lines EMT6 (benign type) and 4T1 (malignant type) were evaluated following treatment with three different doses of meloxicam. The viability and growth of these cells following treatment were determined via cell proliferation and live-dead assays. Cell proliferation assay for these cells showed the absorbance of treated cells was significantly (p<0.05) higher than the control. The live-dead assay showed that the viability of the treated cells was significantly (p<0.05) lower than the control for EMT6 cells while there was no significant difference for the 4T1 cells, however the viability of the treated cells was lower than the control. This study provides preliminary evidence that meloxicam may inhibit growth and viability of mouse mammary tumour cell lines EMT6 and 4T1. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf Cornelius, Cecilia Evelyn and Mohd Noor, Mohd Hezmee (2012) The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1. In: 7th Seminar in Veterinary Sciences, 27 Feb.-2 Mar. 2012, Faculty of Veterinary Medicine, Universiti Putra Malaysia. (p. 80). |
| spellingShingle | Cornelius, Cecilia Evelyn Mohd Noor, Mohd Hezmee The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title | The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title_full | The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title_fullStr | The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title_full_unstemmed | The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title_short | The effects of meloxicam on the growth and viability of mouse mammary tumour cell lines EMT6 and 4T1 |
| title_sort | effects of meloxicam on the growth and viability of mouse mammary tumour cell lines emt6 and 4t1 |
| url | http://psasir.upm.edu.my/id/eprint/26797/ http://psasir.upm.edu.my/id/eprint/26797/1/PROCEEDING%2022.pdf |