Hepatotoxic effect of antifungal drugs itraconazole and fluconazole on rats

QR Code

Hepatotoxic effect of antifungal drugs itraconazole and fluconazole on rats

Itraconazole and fluconazole are synthetic triazole antifungal from azole group. They exhibit fungistatic property by inhibiting ergosterol formation, an important structure in fungal membrane. These drugs have a broad spectrum antifungal activity and been used widely in treating Candida albicans, A...

Full description

Bibliographic Details
Main Author:	Yaacob, Azhar
Format:	Thesis
Language:	English
Published:	2013
Subjects:	Antifungal agents
Online Access:	http://psasir.upm.edu.my/id/eprint/26745/ http://psasir.upm.edu.my/id/eprint/26745/1/FPSK%28m%29%202013%201R.pdf

Similar Items

Hepatotoxicity induced by antifungal drugs itraconazole and fluconazole in rats: a comparative in vivo study
by: Abdullah, Muhammad Nazrul Hakim, et al.
Published: (2004)

Toxicity of Antifungal Drugs Itraconazole and Fluconazole in Rats
by: Abdul Rahman, Nor Shahida
Published: (2004)

Antifungal Peptide Modeling, Folding and Mimetic Design
by: Moradi, Shoeib
Published: (2009)

Potential of Malaysian seaweed extracts in inhibiting Ganoderma boninense and identification of their antifungal compounds
by: Abdul Aziz, Syamimi Diyana
Published: (2018)

Characterization and antifungal properties of oil palm mesocarp fiber superheated steam condensate
by: Sharip, Nur Sharmila
Published: (2016)

Identification of suppression mechanisms and antifungal compounds from Trichoderma virens against Ganoderma boninense
by: Lee, Angel Pei Lee
Published: (2016)

Computational approaches to elucidate the action mechanism of zerumbone towards beta catenin
by: Fatima, Ayesha
Published: (2017)

Itraconazole and fluconazole-induced toxicity in rat hepatocytes: a comparativein vitro study
by: Somchit, N, et al.
Published: (2002)

Antifungal Activities of Selected Medicinal Plant Crude Extracts on Pathogenic Fungi, Colletotrichum Capsici and Colletotrichum Gloeosporioides
by: Johnny, Lucy
Published: (2011)

Metabolomics analysis on antifungal activities produced by Penicillium oxalicum T3.3 grown on different types of carbon sources
by: Salikin, Nurliyana
Published: (2015)

Development of lacto-fermented fungal growth inhibitor coating to extend the shelf life and enhance the quality of mango (Mangifera indica L.)
by: Piyasiri, Fernando Hewage Ranjith
Published: (2022)

The effects of herbal plant extracts on the growth and sporulation of Colletotrhichum gloesporioides
by: Johnny, Lucy, et al.
Published: (2010)

Novel approaches for the control of fungal pathogens
by: Augostine, Catheryn Rachel
Published: (2023)

In silico identification of Meyerozyma guilliermondii strain so potential virulence factors and pathogenicity verification of generated mutants in zebrafish model
by: Lim, Si Jie
Published: (2024)

Effects of fungal treatment on rice straw digestibility and rumen methane mitigation
by: Pauzi, Mohd Azlan
Published: (2015)

Identification of antifungal peptides produced by Lactobacillus plantarum IS10 grown in the MRS broth
by: Muhialdin, Belal J., et al.
Published: (2016)

An evaluation of intravenous antifungal medications in patients in a paediatric hospital
by: Thangavelu Rajan, Remya
Published: (2008)

Growth, biofilm formation, antifungal susceptibility and oxidative stress resistance of Candida glabrata are affected by different glucose concentrations
by: Ng, Tzu Shan, et al.
Published: (2016)

Antifungal activity of synthetic xanthenone against fluconazole-resistant Candida auris and its mechanism of action
by: Ramli, Amirah Hani, et al.
Published: (2024)

Evolution and Gene Flow of Azole Resistance and Other Virulence Factors in Aspergillus fumigatus
by: Alghamdi, Asmaa, et al.
Published: (2022)

Recognition of membrane sterols by polyene antifungals amphotericin B and natamycin, a 13C MAS NMR Study
by: Ciesielski, Filip, et al.
Published: (2016)

In vitro study of antifungal effect of allicin on Aspergillus fumigatus ATCC 36607 growth
by: Sajali, Nurhayatie
Published: (2014)

Attenuation of cisplatin-induced hepatotoxicity in rats using zerumbone.
by: Ibrahim, Mohammed Yousif, et al.
Published: (2009)

Metabolomic Profiling and Genomic Study of a Marine Sponge-Associated Streptomyces sp.
by: Viegelmann, C., et al.
Published: (2014)

Safety of fluconazole in paediatrics: a systematic review
by: Egunsola, Oluwaseun, et al.
Published: (2013)

Metal-based combinations that target protein synthesis by fungi
by: Vallières, Cindy, et al.
Published: (2017)

Protective effect of the ethanol extract of Zingiber officinale Roscoe on Paracetamol Induced Hepatotoxicity in Rats
by: Norina Abdullah,, et al.
Published: (2004)

Effects of curcumin and tartrazine food colorants on biochemical and histochemical parameters in female sprague dawley rats
by: Shakoor, Sadaf
Published: (2019)

Preventive effects of Polygonum minus essential oil on cisplatin-induced hepatotoxicity in sprague dawley rats
by: Norhashima Abd Rashid,, et al.
Published: (2019)

Formulation of nanoemulsions encapsulated with potential anticancer drug, betulinic acid
by: Abdul Rashid, Nur Nadiah
Published: (2014)

Exploitation of fungal sex for biotechnology and disease control
by: Ashton, George David
Published: (2019)

An assessment of agents of hepatotoxicity and neurotoxicity
by: Wijamunige, Buddhika Chameera
Published: (2019)

Antitumor effects of zerumbone on rat hepatocarcinoma and HEPG2 cells
by: Taha, Manal Mohamed Elhassan
Published: (2011)

Topical effects of haruan (Channa striatus bloch)-based cream on inflammation in rats and mice
by: Abedi, Sadegh
Published: (2012)

Hypoglycemic, Hypolipidemic and Histopathological Effects of Brown Seaweed (Sargassum Polycystum C. Agardh) Extracts on Type 2 Diabetic Rats
by: Moteshakeri, Mahsa
Published: (2011)

Lycopene and Red Palm Oil Effects on Hypoglycemics and Antioxidant in Streptozotocin-Induced Diabetic Rats
by: Ebadi, Seyed Morteza
Published: (2011)

Moringa oleifera hydroethanolic extracts effectively alleviate acetaminophen-induced hepatotoxicity in experimental rats through their antioxidant nature
by: Fakurazi, Sharida, et al.
Published: (2012)

Polyunsaturated fatty acids from eel extract attenuate gastritis and hepatotoxic by Indomethacin-induced in rats
by: Sasongko, Heru, et al.
Published: (2023)

Amelioration of paracetamol-induced hepatotoxicity in rat by the administration of methanol extract of Muntingia calabura L. leaves
by: Mahmood, Nur Diyana, et al.
Published: (2014)

Antidiabetic effects of Melicope lunu-ankenda (Gaertn.) T.G. Hartley on obese STZ-induced diabetic rats using NMR-based metabolomics
by: Baroor Al-Zuaidy, Mizher Hezam
Published: (2016)