Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.

A single Leptospira strain (designated Bejo-Iso9T) was isolated from a soil sample taken in Johor, Malaysia. The isolate showed motility and morphology typical of the genus Leptospira under darkfield microscopy. Cells were found to be 10–13 mm in length and 0.2 mm in diameter, with a wavelength o...

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Main Authors: Slack, Andrew T., Bejo, Siti Khairani, Symonds, Meegan L., Dohnt, Michael F., Galloway, Renee L., Steigerwalt, Arnold G., Bahaman, Abdul Rani, Craig, Scott, Harrower, Bruce J., Smythe, Lee D.
Format: Article
Language:English
Published: Society for General Microbiology 2009
Online Access:http://psasir.upm.edu.my/id/eprint/25683/
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author Slack, Andrew T.
Bejo, Siti Khairani
Symonds, Meegan L.
Dohnt, Michael F.
Galloway, Renee L.
Steigerwalt, Arnold G.
Bahaman, Abdul Rani
Craig, Scott
Harrower, Bruce J.
Smythe, Lee D.
author_facet Slack, Andrew T.
Bejo, Siti Khairani
Symonds, Meegan L.
Dohnt, Michael F.
Galloway, Renee L.
Steigerwalt, Arnold G.
Bahaman, Abdul Rani
Craig, Scott
Harrower, Bruce J.
Smythe, Lee D.
author_sort Slack, Andrew T.
building UPM Institutional Repository
collection Online Access
description A single Leptospira strain (designated Bejo-Iso9T) was isolated from a soil sample taken in Johor, Malaysia. The isolate showed motility and morphology typical of the genus Leptospira under darkfield microscopy. Cells were found to be 10–13 mm in length and 0.2 mm in diameter, with a wavelength of 0.5 mm and an amplitude of approximately 0.2 mm. Phenotypically, strain Bejo- Iso9T grew in Ellinghausen–McCullough–Johnson–Harris medium at 13, 30 and 37 6C, and also in the presence of 8-azaguanine. Serologically, strain Bejo-Iso9T produced titres towards several members of the Tarassovi serogroup, but was found to be serologically unique by cross-agglutinin absorption test and thus represented a novel serovar. The proposed name for this serovar is Malaysia. Phylogenetic analysis of 16S rRNA gene sequences placed this novel strain within the radiation of the genus Leptospira, with sequence similarities within the range 90.4–99.5% with respect to recognized Leptospira species. DNA–DNA hybridization against the three most closely related Leptospira species was used to confirm the results of the 16S rRNA gene sequence analysis. The G+C content of the genome of strain Bejo-Iso9T was 36.2 mol%. On the basis of phenotypic, serological and phylogenetic data, strain Bejo-Iso9T represents a novel species of the genus Leptospira, for which the name Leptospira kmetyi sp. nov. is proposed. The type strain is Bejo-Iso9T (5WHO LT1101T5KIT Bejo-Iso9T).
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spelling upm-256832014-01-13T06:33:36Z http://psasir.upm.edu.my/id/eprint/25683/ Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia. Slack, Andrew T. Bejo, Siti Khairani Symonds, Meegan L. Dohnt, Michael F. Galloway, Renee L. Steigerwalt, Arnold G. Bahaman, Abdul Rani Craig, Scott Harrower, Bruce J. Smythe, Lee D. A single Leptospira strain (designated Bejo-Iso9T) was isolated from a soil sample taken in Johor, Malaysia. The isolate showed motility and morphology typical of the genus Leptospira under darkfield microscopy. Cells were found to be 10–13 mm in length and 0.2 mm in diameter, with a wavelength of 0.5 mm and an amplitude of approximately 0.2 mm. Phenotypically, strain Bejo- Iso9T grew in Ellinghausen–McCullough–Johnson–Harris medium at 13, 30 and 37 6C, and also in the presence of 8-azaguanine. Serologically, strain Bejo-Iso9T produced titres towards several members of the Tarassovi serogroup, but was found to be serologically unique by cross-agglutinin absorption test and thus represented a novel serovar. The proposed name for this serovar is Malaysia. Phylogenetic analysis of 16S rRNA gene sequences placed this novel strain within the radiation of the genus Leptospira, with sequence similarities within the range 90.4–99.5% with respect to recognized Leptospira species. DNA–DNA hybridization against the three most closely related Leptospira species was used to confirm the results of the 16S rRNA gene sequence analysis. The G+C content of the genome of strain Bejo-Iso9T was 36.2 mol%. On the basis of phenotypic, serological and phylogenetic data, strain Bejo-Iso9T represents a novel species of the genus Leptospira, for which the name Leptospira kmetyi sp. nov. is proposed. The type strain is Bejo-Iso9T (5WHO LT1101T5KIT Bejo-Iso9T). Society for General Microbiology 2009 Article PeerReviewed Slack, Andrew T. and Bejo, Siti Khairani and Symonds, Meegan L. and Dohnt, Michael F. and Galloway, Renee L. and Steigerwalt, Arnold G. and Bahaman, Abdul Rani and Craig, Scott and Harrower, Bruce J. and Smythe, Lee D. (2009) Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia. International Journal of Systematic and Evolutionary Microbiology, 59 (4). pp. 705-708. ISSN 1466-5026; ESSN : 1466-5034 10.1099/ijs.0.002766-0 English
spellingShingle Slack, Andrew T.
Bejo, Siti Khairani
Symonds, Meegan L.
Dohnt, Michael F.
Galloway, Renee L.
Steigerwalt, Arnold G.
Bahaman, Abdul Rani
Craig, Scott
Harrower, Bruce J.
Smythe, Lee D.
Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title_full Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title_fullStr Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title_full_unstemmed Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title_short Leptospira kmetyi sp. nov., isolated from an environmental source in Malaysia.
title_sort leptospira kmetyi sp. nov., isolated from an environmental source in malaysia.
url http://psasir.upm.edu.my/id/eprint/25683/
http://psasir.upm.edu.my/id/eprint/25683/