Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats

The efficacy of exercise and dietary polyunsaturated fatty acid (PUFA) on streptozotocin-induced diabetes in rats was investigated based on blood lipid profiles, with respect to triglycerides, total cholesterol, high-density lipoprotein (HDL)-cholesterol, and low-density lipoprotein (LDL)-cholestero...

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Main Authors: Abu Hassim, Hasliza, Mohamed Mustapha, Noordin, Goh, Yong Meng
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2011
Online Access:http://psasir.upm.edu.my/id/eprint/25430/
http://psasir.upm.edu.my/id/eprint/25430/1/18%20Pg%20151-156.pdf
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author Abu Hassim, Hasliza
Mohamed Mustapha, Noordin
Goh, Yong Meng
author_facet Abu Hassim, Hasliza
Mohamed Mustapha, Noordin
Goh, Yong Meng
author_sort Abu Hassim, Hasliza
building UPM Institutional Repository
collection Online Access
description The efficacy of exercise and dietary polyunsaturated fatty acid (PUFA) on streptozotocin-induced diabetes in rats was investigated based on blood lipid profiles, with respect to triglycerides, total cholesterol, high-density lipoprotein (HDL)-cholesterol, and low-density lipoprotein (LDL)-cholesterol. A total of 32 Sprague-Dawley male rats were used and divided into eight groups. Four groups were exercised daily for 8 weeks, while the other four were sedentary. Treatment diets were defined as follows: rat chow diet only (Control diet), rat chow added with 2:1, menhaden oil:soybean oil (Diet 1), rat chow added with 1:2, menhaden oil:soybean oil (Diet 2), and rat chow added with 10% (w/w) butter (Diet 3). Blood plasma was collected at the end of 8 weeks for blood lipid profiles determination. The results showed that a combination of exercise and dietary PUFA significantly improved lipid abnormalities by lowering the triglycerides, total cholesterol, and LDL-cholesterol levels.
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spelling upm-254302016-11-21T07:32:49Z http://psasir.upm.edu.my/id/eprint/25430/ Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats Abu Hassim, Hasliza Mohamed Mustapha, Noordin Goh, Yong Meng The efficacy of exercise and dietary polyunsaturated fatty acid (PUFA) on streptozotocin-induced diabetes in rats was investigated based on blood lipid profiles, with respect to triglycerides, total cholesterol, high-density lipoprotein (HDL)-cholesterol, and low-density lipoprotein (LDL)-cholesterol. A total of 32 Sprague-Dawley male rats were used and divided into eight groups. Four groups were exercised daily for 8 weeks, while the other four were sedentary. Treatment diets were defined as follows: rat chow diet only (Control diet), rat chow added with 2:1, menhaden oil:soybean oil (Diet 1), rat chow added with 1:2, menhaden oil:soybean oil (Diet 2), and rat chow added with 10% (w/w) butter (Diet 3). Blood plasma was collected at the end of 8 weeks for blood lipid profiles determination. The results showed that a combination of exercise and dietary PUFA significantly improved lipid abnormalities by lowering the triglycerides, total cholesterol, and LDL-cholesterol levels. Universiti Putra Malaysia Press 2011-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/25430/1/18%20Pg%20151-156.pdf Abu Hassim, Hasliza and Mohamed Mustapha, Noordin and Goh, Yong Meng (2011) Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats. Pertanika Journal of Tropical Agricultural Science, 34 (1). pp. 151-155. ISSN 1511-3701; ESSN: 2231-8542 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2034%20(1)%20Feb.%202011/18%20Pg%20151-156.pdf
spellingShingle Abu Hassim, Hasliza
Mohamed Mustapha, Noordin
Goh, Yong Meng
Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title_full Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title_fullStr Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title_full_unstemmed Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title_short Effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
title_sort effects of exercise and dietary polyunsaturated fatty acid on blood lipid profiles of streptozotocin-induced diabetes in rats
url http://psasir.upm.edu.my/id/eprint/25430/
http://psasir.upm.edu.my/id/eprint/25430/
http://psasir.upm.edu.my/id/eprint/25430/1/18%20Pg%20151-156.pdf