Melamin toxicity in pigs
Three farms in Penang, Malaysia, reported illness in grower-finisher pigs with discarded kidneys from abattoir. Affected animals were inappetant, anorexic, thin, dull, and depressed. The episode was closely related with the feed formulation changes, where soybean and fishmeal were replaced with yeas...
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia Press
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/25350/ http://psasir.upm.edu.my/id/eprint/25350/1/35.%20Melamine%20Toxicity%20in%20Pigs.pdf |
| _version_ | 1848845286181437440 |
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| author | Lee, C. H. Ooi, Peck Toung Sheikh Omar, Abdul Rahman Lim, B. K. |
| author_facet | Lee, C. H. Ooi, Peck Toung Sheikh Omar, Abdul Rahman Lim, B. K. |
| author_sort | Lee, C. H. |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Three farms in Penang, Malaysia, reported illness in grower-finisher pigs with discarded kidneys from abattoir. Affected animals were inappetant, anorexic, thin, dull, and depressed. The episode was closely related with the feed formulation changes, where soybean and fishmeal were replaced with yeast. No significant mycotoxin levels were detected in both the feed and yeasts. However, high levels of melamine were detected in yeast (30,064 ppm) and finished feed (750 to 1500 ppm), which exceeded the acceptance level set by WHO (<2.5 ppm). Nonetheless, prominent gross abnormalities were detected, except for the lesions in the kidneys during necropsy. The affected kidneys were enlarged and yellowish in colour, firm in consistency and the cortical surface was wrinkled and dimpled. Dilated cortical and medullary lesions with yellow gritty crystalline materials were also observed. A microscopic examination revealed the lesions of acute tubular nephrosis, interstitial nephritis with multiple cysts in the kidney cortex. After the removal of the yeast source in the feed, the illness and kidney lesions were in remission. |
| first_indexed | 2025-11-15T08:44:24Z |
| format | Article |
| id | upm-25350 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:44:24Z |
| publishDate | 2011 |
| publisher | Universiti Putra Malaysia Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-253502015-11-03T02:56:16Z http://psasir.upm.edu.my/id/eprint/25350/ Melamin toxicity in pigs Lee, C. H. Ooi, Peck Toung Sheikh Omar, Abdul Rahman Lim, B. K. Three farms in Penang, Malaysia, reported illness in grower-finisher pigs with discarded kidneys from abattoir. Affected animals were inappetant, anorexic, thin, dull, and depressed. The episode was closely related with the feed formulation changes, where soybean and fishmeal were replaced with yeast. No significant mycotoxin levels were detected in both the feed and yeasts. However, high levels of melamine were detected in yeast (30,064 ppm) and finished feed (750 to 1500 ppm), which exceeded the acceptance level set by WHO (<2.5 ppm). Nonetheless, prominent gross abnormalities were detected, except for the lesions in the kidneys during necropsy. The affected kidneys were enlarged and yellowish in colour, firm in consistency and the cortical surface was wrinkled and dimpled. Dilated cortical and medullary lesions with yellow gritty crystalline materials were also observed. A microscopic examination revealed the lesions of acute tubular nephrosis, interstitial nephritis with multiple cysts in the kidney cortex. After the removal of the yeast source in the feed, the illness and kidney lesions were in remission. Universiti Putra Malaysia Press 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/25350/1/35.%20Melamine%20Toxicity%20in%20Pigs.pdf Lee, C. H. and Ooi, Peck Toung and Sheikh Omar, Abdul Rahman and Lim, B. K. (2011) Melamin toxicity in pigs. Pertanika Journal of Tropical Agricultural Science, 34 (1). pp. 175-179. ISSN 1511-3701; ESSN: 2231-8542 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2034%20(1)%20Feb.%202011/22%20Pg%20175-180.pdf |
| spellingShingle | Lee, C. H. Ooi, Peck Toung Sheikh Omar, Abdul Rahman Lim, B. K. Melamin toxicity in pigs |
| title | Melamin toxicity in pigs |
| title_full | Melamin toxicity in pigs |
| title_fullStr | Melamin toxicity in pigs |
| title_full_unstemmed | Melamin toxicity in pigs |
| title_short | Melamin toxicity in pigs |
| title_sort | melamin toxicity in pigs |
| url | http://psasir.upm.edu.my/id/eprint/25350/ http://psasir.upm.edu.my/id/eprint/25350/ http://psasir.upm.edu.my/id/eprint/25350/1/35.%20Melamine%20Toxicity%20in%20Pigs.pdf |