Utilization of I-domain of LFA-1 to target drug and marker molecules to Leukocytes.

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Utilization of I-domain of LFA-1 to target drug and marker molecules to Leukocytes.

The long-term objective of this project is to utilize the I-domain protein for the α-subunit of LFA-1 to target drugs to lymphocytes by binding to ICAM receptors on the cell surface. The short-term goal is to provide proof-of-concept that I-domain conjugated to small molecules can still bind to and...

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Bibliographic Details
Main Authors:	Manikwar, Prakash, Tejo, Bimo Ario, Shinogle, Heather, Moore, David S., Zimmerman, Tahl, Blanco, Francisco, Siahaan, Teruna J.
Format:	Article
Language:	English English
Published:	Ivyspring International Publisher 2011
Online Access:	http://psasir.upm.edu.my/id/eprint/25114/ http://psasir.upm.edu.my/id/eprint/25114/1/Utilization%20of%20I.pdf

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