Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.

The complexation of the dithiocarbazate ion (DTCA−) with various metal ions, viz., Sn(II)/(IV), Bi(III), Sb(III), U(VI), Zr(IV), Th(IV), Al(III), Ni(II), Zn(II), and Cu(II) was investigated. Most of the complexes were hexa-coordinated with the exception of Cu(II), Ni(II), and Zn(II) complexes that w...

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Main Authors: Tarafder, M.T.H., Ali, A.M., Wong, Y.W., Wong, S.H., Crouse, Karen Anne
Format: Article
Language:English
English
Published: Taylor & Francis 2001
Online Access:http://psasir.upm.edu.my/id/eprint/25091/
http://psasir.upm.edu.my/id/eprint/25091/1/Complexes%20of%20transition%20and%20nontransition%20metals%20of%20dithiocarbazate%20ion%20and%20their%20biological%20activities.pdf
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author Tarafder, M.T.H.
Ali, A.M.
Wong, Y.W.
Wong, S.H.
Crouse, Karen Anne
author_facet Tarafder, M.T.H.
Ali, A.M.
Wong, Y.W.
Wong, S.H.
Crouse, Karen Anne
author_sort Tarafder, M.T.H.
building UPM Institutional Repository
collection Online Access
description The complexation of the dithiocarbazate ion (DTCA−) with various metal ions, viz., Sn(II)/(IV), Bi(III), Sb(III), U(VI), Zr(IV), Th(IV), Al(III), Ni(II), Zn(II), and Cu(II) was investigated. Most of the complexes were hexa-coordinated with the exception of Cu(II), Ni(II), and Zn(II) complexes that were four-coordinated. The biological properties of the metal complexes revealed that in general the complexes of nontransition metals were more effective against microorganisms than those of transition metals. In particular, [Sb(DTCA)Cl2·2H2O] and [Al(DTCA)Cl2·2H2O] were found to have strong antimicrobial activities. A minimum inhibitory concentration of 300 μg/mL was recorded for the above two complexes against Pseudomonas aeruginosa while that against Bacillus cereus was found to be 700 μg/mL. None of the complexes were cytotoxic.
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spelling upm-250912016-01-21T04:15:22Z http://psasir.upm.edu.my/id/eprint/25091/ Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities. Tarafder, M.T.H. Ali, A.M. Wong, Y.W. Wong, S.H. Crouse, Karen Anne The complexation of the dithiocarbazate ion (DTCA−) with various metal ions, viz., Sn(II)/(IV), Bi(III), Sb(III), U(VI), Zr(IV), Th(IV), Al(III), Ni(II), Zn(II), and Cu(II) was investigated. Most of the complexes were hexa-coordinated with the exception of Cu(II), Ni(II), and Zn(II) complexes that were four-coordinated. The biological properties of the metal complexes revealed that in general the complexes of nontransition metals were more effective against microorganisms than those of transition metals. In particular, [Sb(DTCA)Cl2·2H2O] and [Al(DTCA)Cl2·2H2O] were found to have strong antimicrobial activities. A minimum inhibitory concentration of 300 μg/mL was recorded for the above two complexes against Pseudomonas aeruginosa while that against Bacillus cereus was found to be 700 μg/mL. None of the complexes were cytotoxic. Taylor & Francis 2001 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/25091/1/Complexes%20of%20transition%20and%20nontransition%20metals%20of%20dithiocarbazate%20ion%20and%20their%20biological%20activities.pdf Tarafder, M.T.H. and Ali, A.M. and Wong, Y.W. and Wong, S.H. and Crouse, Karen Anne (2001) Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities. Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 31 (1). pp. 115-125. ISSN 0094-5714 http://www.tandf.co.uk/journals/default.asp 10.1081/SIM-100001937 English
spellingShingle Tarafder, M.T.H.
Ali, A.M.
Wong, Y.W.
Wong, S.H.
Crouse, Karen Anne
Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title_full Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title_fullStr Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title_full_unstemmed Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title_short Complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
title_sort complexes of transition and nontransition metals of dithiocarbazate ion and their biological activities.
url http://psasir.upm.edu.my/id/eprint/25091/
http://psasir.upm.edu.my/id/eprint/25091/
http://psasir.upm.edu.my/id/eprint/25091/
http://psasir.upm.edu.my/id/eprint/25091/1/Complexes%20of%20transition%20and%20nontransition%20metals%20of%20dithiocarbazate%20ion%20and%20their%20biological%20activities.pdf