Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network.
An Artificial Neural Network (ANN) based on the Quick Propagation (QP) algorithm was used in conjunction with an experimental design to optimize the lipase-catalyzed reaction conditions for the preparation of a triethanolamine (TEA)-based esterquat cationic surfactant. Using the best performing ANN,...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
MDPI
2011
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/24952/ http://psasir.upm.edu.my/id/eprint/24952/1/Multivariate%20optimization%20in%20the%20biosynthesis%20of%20a%20triethanolamine.pdf |
| _version_ | 1848845176348344320 |
|---|---|
| author | Fard Masoumi, Hamid Reza Kassim, Anuar Basri, Mahiran Abdullah, Dzulkefly Kuang Haron, Md. Jelas |
| author_facet | Fard Masoumi, Hamid Reza Kassim, Anuar Basri, Mahiran Abdullah, Dzulkefly Kuang Haron, Md. Jelas |
| author_sort | Fard Masoumi, Hamid Reza |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | An Artificial Neural Network (ANN) based on the Quick Propagation (QP) algorithm was used in conjunction with an experimental design to optimize the lipase-catalyzed reaction conditions for the preparation of a triethanolamine (TEA)-based esterquat cationic surfactant. Using the best performing ANN, the optimum conditions
predicted were an enzyme amount of 4.77 w/w%, reaction time of 24 h, reaction temperature of 61.9 °C, substrate (oleic acid: triethanolamine) molar ratio of 1:1 mole and
agitation speed of 480 r.p.m. The relative deviation percentage under these conditions was less than 4%. The optimized method was successfully applied to the synthesis of the TEA-based esterquat cationic surfactant at a 2,000 mL scale. This method represents a more flexible and convenient means for optimizing enzymatic reaction using ANN than has been previously reported by conventional methods. |
| first_indexed | 2025-11-15T08:42:39Z |
| format | Article |
| id | upm-24952 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:42:39Z |
| publishDate | 2011 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-249522015-09-21T04:04:27Z http://psasir.upm.edu.my/id/eprint/24952/ Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. Fard Masoumi, Hamid Reza Kassim, Anuar Basri, Mahiran Abdullah, Dzulkefly Kuang Haron, Md. Jelas An Artificial Neural Network (ANN) based on the Quick Propagation (QP) algorithm was used in conjunction with an experimental design to optimize the lipase-catalyzed reaction conditions for the preparation of a triethanolamine (TEA)-based esterquat cationic surfactant. Using the best performing ANN, the optimum conditions predicted were an enzyme amount of 4.77 w/w%, reaction time of 24 h, reaction temperature of 61.9 °C, substrate (oleic acid: triethanolamine) molar ratio of 1:1 mole and agitation speed of 480 r.p.m. The relative deviation percentage under these conditions was less than 4%. The optimized method was successfully applied to the synthesis of the TEA-based esterquat cationic surfactant at a 2,000 mL scale. This method represents a more flexible and convenient means for optimizing enzymatic reaction using ANN than has been previously reported by conventional methods. MDPI 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24952/1/Multivariate%20optimization%20in%20the%20biosynthesis%20of%20a%20triethanolamine.pdf Fard Masoumi, Hamid Reza and Kassim, Anuar and Basri, Mahiran and Abdullah, Dzulkefly Kuang and Haron, Md. Jelas (2011) Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. Molecules, 16 (7). pp. 5538-5549. ISSN 1420-3049 http://www.mdpi.com/ 10.3390/molecules16075538 English |
| spellingShingle | Fard Masoumi, Hamid Reza Kassim, Anuar Basri, Mahiran Abdullah, Dzulkefly Kuang Haron, Md. Jelas Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title | Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title_full | Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title_fullStr | Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title_full_unstemmed | Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title_short | Multivariate optimization in the biosynthesis of a triethanolamine (TEA)-based esterquat cationic surfactant using an artificial neural network. |
| title_sort | multivariate optimization in the biosynthesis of a triethanolamine (tea)-based esterquat cationic surfactant using an artificial neural network. |
| url | http://psasir.upm.edu.my/id/eprint/24952/ http://psasir.upm.edu.my/id/eprint/24952/ http://psasir.upm.edu.my/id/eprint/24952/ http://psasir.upm.edu.my/id/eprint/24952/1/Multivariate%20optimization%20in%20the%20biosynthesis%20of%20a%20triethanolamine.pdf |