Alpha-mangostin and beta-mangostin from Cratoxylum laucum.
Our continuing interest in xanthones and anthraquinones from the Cratoxylum genus has led us to look at Cratoxylum glaucum. This resulted in the isolation of alpha-mangostin (1), beta-mangostin (2), fuscaxanthone C (3), 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone (4), beta-sitosterol (5), 1,8-d...
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| Format: | Article |
| Language: | English English |
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International Congress of Chemistry and Environment
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24896/ http://psasir.upm.edu.my/id/eprint/24896/1/Alpha.pdf |
| _version_ | 1848845160789573632 |
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| author | Ee, Gwendoline Cheng Lian Md.Sukari, Mohd. Aspollah Wei , Chung Sim |
| author_facet | Ee, Gwendoline Cheng Lian Md.Sukari, Mohd. Aspollah Wei , Chung Sim |
| author_sort | Ee, Gwendoline Cheng Lian |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Our continuing interest in xanthones and anthraquinones from the Cratoxylum genus has led us to look at Cratoxylum glaucum. This resulted in the isolation of alpha-mangostin (1), beta-mangostin (2), fuscaxanthone C (3), 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone (4), beta-sitosterol (5), 1,8-dihydroxy-3-methoxy-6-methylanthraquinone (6), stigmasterol (7), friedelin (8) and betulinic acid (9). Structural elucidations of these compounds were achieved by using ID and 2D NMR spectroscopic experiments. Cytotoxic assays indicated that the hexane and ethyl acetate extracts demonstrated cytotoxicity against the MCF7 cancer cell line. Meanwhile, the ethyl acetate and methanol extracts of C. glaucum inhibited the HL-60 cancer cell line activity. |
| first_indexed | 2025-11-15T08:42:24Z |
| format | Article |
| id | upm-24896 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:42:24Z |
| publishDate | 2011 |
| publisher | International Congress of Chemistry and Environment |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-248962015-09-09T04:54:55Z http://psasir.upm.edu.my/id/eprint/24896/ Alpha-mangostin and beta-mangostin from Cratoxylum laucum. Ee, Gwendoline Cheng Lian Md.Sukari, Mohd. Aspollah Wei , Chung Sim Our continuing interest in xanthones and anthraquinones from the Cratoxylum genus has led us to look at Cratoxylum glaucum. This resulted in the isolation of alpha-mangostin (1), beta-mangostin (2), fuscaxanthone C (3), 3-geranyloxy-6-methyl-1,8-dihydroxyanthraquinone (4), beta-sitosterol (5), 1,8-dihydroxy-3-methoxy-6-methylanthraquinone (6), stigmasterol (7), friedelin (8) and betulinic acid (9). Structural elucidations of these compounds were achieved by using ID and 2D NMR spectroscopic experiments. Cytotoxic assays indicated that the hexane and ethyl acetate extracts demonstrated cytotoxicity against the MCF7 cancer cell line. Meanwhile, the ethyl acetate and methanol extracts of C. glaucum inhibited the HL-60 cancer cell line activity. International Congress of Chemistry and Environment 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24896/1/Alpha.pdf Ee, Gwendoline Cheng Lian and Md.Sukari, Mohd. Aspollah and Wei , Chung Sim (2011) Alpha-mangostin and beta-mangostin from Cratoxylum laucum. Research Journal of Chemistry and Environment, 15 (2). pp. 62-66. ISSN 0972-0626 http://www.waset.org/ English |
| spellingShingle | Ee, Gwendoline Cheng Lian Md.Sukari, Mohd. Aspollah Wei , Chung Sim Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title | Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title_full | Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title_fullStr | Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title_full_unstemmed | Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title_short | Alpha-mangostin and beta-mangostin from Cratoxylum laucum. |
| title_sort | alpha-mangostin and beta-mangostin from cratoxylum laucum. |
| url | http://psasir.upm.edu.my/id/eprint/24896/ http://psasir.upm.edu.my/id/eprint/24896/ http://psasir.upm.edu.my/id/eprint/24896/1/Alpha.pdf |