Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode.
A sensitive voltammetric method for detection of mercury ions is described which is made by modifying a gold electrode with 3-mercaptopropionic acid followed by covalent attachment of the octapeptide His-Phe-His-Ala-His-Phe-Ala-Phe to the self-assembled monolayer using carbodiimide coupling. A linea...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English English |
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2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24879/ http://psasir.upm.edu.my/id/eprint/24879/1/Development%20of%20electrochemical%20sensor%20for%20detection%20of%20mercury%20by%20exploiting%20His.pdf |
| _version_ | 1848845156260773888 |
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| author | Daud, Nurulhaidah Yusof, Nor Azah Tan, Wee Tee |
| author_facet | Daud, Nurulhaidah Yusof, Nor Azah Tan, Wee Tee |
| author_sort | Daud, Nurulhaidah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A sensitive voltammetric method for detection of mercury ions is described which is made by modifying a gold electrode with 3-mercaptopropionic acid followed by covalent attachment of the octapeptide His-Phe-His-Ala-His-Phe-Ala-Phe to the self-assembled monolayer using carbodiimide coupling. A linear working range for concentration of mercury between 0.25 to 0.81 with LOD 9.5×10 -9 M was obtained which is below the WHO guidelines for drinking water. The reproducibility of the analytical signal is 4.5% in indicating a reproducible and reliable detection system. The developed method was applied for the detection of Hg(II) in spiked wastewater and validated against ICPMS. Good agreement was obtained between the developed method and ICPMS. Insignificant interference was observed by As 3+, Cr 3+, Cu 2+, Ni 2+, Pb 2+and Zn 2+ in detection of Hg(II) thus making the developed system highly potential for electrochemical sensor in Hg(II) detection. |
| first_indexed | 2025-11-15T08:42:20Z |
| format | Article |
| id | upm-24879 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:42:20Z |
| publishDate | 2011 |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-248792015-10-08T08:43:32Z http://psasir.upm.edu.my/id/eprint/24879/ Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. Daud, Nurulhaidah Yusof, Nor Azah Tan, Wee Tee A sensitive voltammetric method for detection of mercury ions is described which is made by modifying a gold electrode with 3-mercaptopropionic acid followed by covalent attachment of the octapeptide His-Phe-His-Ala-His-Phe-Ala-Phe to the self-assembled monolayer using carbodiimide coupling. A linear working range for concentration of mercury between 0.25 to 0.81 with LOD 9.5×10 -9 M was obtained which is below the WHO guidelines for drinking water. The reproducibility of the analytical signal is 4.5% in indicating a reproducible and reliable detection system. The developed method was applied for the detection of Hg(II) in spiked wastewater and validated against ICPMS. Good agreement was obtained between the developed method and ICPMS. Insignificant interference was observed by As 3+, Cr 3+, Cu 2+, Ni 2+, Pb 2+and Zn 2+ in detection of Hg(II) thus making the developed system highly potential for electrochemical sensor in Hg(II) detection. 2011-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24879/1/Development%20of%20electrochemical%20sensor%20for%20detection%20of%20mercury%20by%20exploiting%20His.pdf Daud, Nurulhaidah and Yusof, Nor Azah and Tan, Wee Tee (2011) Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. International Journal Electrochemistry Science, 6 (7). pp. 2798-2807. ISSN 1452-3981 English |
| spellingShingle | Daud, Nurulhaidah Yusof, Nor Azah Tan, Wee Tee Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title | Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title_full | Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title_fullStr | Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title_full_unstemmed | Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title_short | Development of electrochemical sensor for detection of mercury by exploiting His-Phe-His-Ala-His-Phe-Ala-Phe modified electrode. |
| title_sort | development of electrochemical sensor for detection of mercury by exploiting his-phe-his-ala-his-phe-ala-phe modified electrode. |
| url | http://psasir.upm.edu.my/id/eprint/24879/ http://psasir.upm.edu.my/id/eprint/24879/1/Development%20of%20electrochemical%20sensor%20for%20detection%20of%20mercury%20by%20exploiting%20His.pdf |