A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc.
A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)- enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydroxy-4,4′,6′-trimethoxychalcone, (24S)-24-methy...
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| Format: | Article |
| Language: | English English |
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MDPI
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24796/ http://psasir.upm.edu.my/id/eprint/24796/1/A%20new%20abietene%20diterpene%20and%20other%20constituents%20from%20Kaempferia%20angustifolia%20Rosc.pdf |
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| author | Tang, Sook Wah Md.Sukari, Mohd. Aspollah Rahmani, Mawardi Lajis, Md. Nordin Ali, Abdul Manaf |
| author_facet | Tang, Sook Wah Md.Sukari, Mohd. Aspollah Rahmani, Mawardi Lajis, Md. Nordin Ali, Abdul Manaf |
| author_sort | Tang, Sook Wah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)-
enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol,
2′-hydroxy-4,4′,6′-trimethoxychalcone, (24S)-24-methyl-5α-lanosta-9(11),25-dien-3β-ol, β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside. The structures of all compounds were elucidated on the basis of mass spectroscopic and NMR data. Zeylenol (2), the major
constituent of the plant, was derivatized into diacetate, triacetate and epoxide derivatives through standard organic reactions. The cytotoxic activity of compounds 1, 2 and the
zeylenol derivatives was evaluated against the HL-60, MCF-7, HT-29 and HeLa cell lines. |
| first_indexed | 2025-11-15T08:41:59Z |
| format | Article |
| id | upm-24796 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:41:59Z |
| publishDate | 2011 |
| publisher | MDPI |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-247962016-01-12T07:11:35Z http://psasir.upm.edu.my/id/eprint/24796/ A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. Tang, Sook Wah Md.Sukari, Mohd. Aspollah Rahmani, Mawardi Lajis, Md. Nordin Ali, Abdul Manaf A new abietene diterpene, kaempfolienol (5S,6S,7S,9S,10S,11R,13S-abiet-8(14)- enepenta-6,7,9,11,13-ol, 1), was isolated from a rhizome extract of Kaempferia angustifolia Rosc. along with the known compounds crotepoxide, boesenboxide, zeylenol, 2′-hydroxy-4,4′,6′-trimethoxychalcone, (24S)-24-methyl-5α-lanosta-9(11),25-dien-3β-ol, β-sitosterol and β-sitosterol-3-O-β-D-glucopyranoside. The structures of all compounds were elucidated on the basis of mass spectroscopic and NMR data. Zeylenol (2), the major constituent of the plant, was derivatized into diacetate, triacetate and epoxide derivatives through standard organic reactions. The cytotoxic activity of compounds 1, 2 and the zeylenol derivatives was evaluated against the HL-60, MCF-7, HT-29 and HeLa cell lines. MDPI 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24796/1/A%20new%20abietene%20diterpene%20and%20other%20constituents%20from%20Kaempferia%20angustifolia%20Rosc.pdf Tang, Sook Wah and Md.Sukari, Mohd. Aspollah and Rahmani, Mawardi and Lajis, Md. Nordin and Ali, Abdul Manaf (2011) A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. Molecules, 16. pp. 3018-3028. ISSN 1431-5157; ESSN: 1420-3049 10.3390/molecules16043018 English |
| spellingShingle | Tang, Sook Wah Md.Sukari, Mohd. Aspollah Rahmani, Mawardi Lajis, Md. Nordin Ali, Abdul Manaf A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title | A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title_full | A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title_fullStr | A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title_full_unstemmed | A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title_short | A new abietene diterpene and other constituents from Kaempferia angustifolia Rosc. |
| title_sort | new abietene diterpene and other constituents from kaempferia angustifolia rosc. |
| url | http://psasir.upm.edu.my/id/eprint/24796/ http://psasir.upm.edu.my/id/eprint/24796/ http://psasir.upm.edu.my/id/eprint/24796/1/A%20new%20abietene%20diterpene%20and%20other%20constituents%20from%20Kaempferia%20angustifolia%20Rosc.pdf |