Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode.
Nanoparticles of bismuth oxide (Bi2O3) have been mechanically attached on the surface of a glassy carbon electrode. Electrochemical performance of nanoparticles of Bi2O3/GC modified electrode shows stable response with enhanced selectivity and sensitivity. Voltammetric determination of the oxidatio...
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| Format: | Article |
| Language: | English English |
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Electrochemical Science Group
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24776/ http://psasir.upm.edu.my/id/eprint/24776/1/Electrochemical%20oxidation%20of%20paracetamol%20mediated%20by%20nanoparticles%20bismuth%20oxide%20modified%20glassy%20carbon%20electrode.pdf |
| _version_ | 1848845128689516544 |
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| author | Mohammed Zidan, Tan, Wee Tee Abdullah, Abdul Halim Zainal, Zulkarnain Goh, Joo Kheng |
| author_facet | Mohammed Zidan, Tan, Wee Tee Abdullah, Abdul Halim Zainal, Zulkarnain Goh, Joo Kheng |
| author_sort | Mohammed Zidan, |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Nanoparticles of bismuth oxide (Bi2O3) have been mechanically attached on the surface of a glassy carbon electrode. Electrochemical performance of nanoparticles of Bi2O3/GC modified electrode shows stable response with enhanced selectivity and sensitivity. Voltammetric determination of the oxidation of paracetamol in 0.1 M KH2PO4 electrolyte solution by solid phase voltammetry has shown electrocatalyzing effect. Observation revealed a high peak toward the origin of paracetamol oxidation current, which showed 2.0 times increment as compared to bare GC electrode. The sensitivity under conditions of cyclic voltammetry is significantly dependent on pH and temperature. The variation of scan rate study shows that the system undergoes diffusion-controlled process. Calibration plot reveals linearity from the range 5.0 × 10-7 to 1.5 × 10-3M with a correlation coefficient of 0.994. The detection limit was estimated to be 2.0 × 10-7 M. Based on interference studies, most amino acids have negligibly affected the current response of paracetamol. Practically, nanoparticles of bismuth oxide (Bi2O3) modified GC electrode could be used for the determination of parecetamol in blood plasma samples. |
| first_indexed | 2025-11-15T08:41:54Z |
| format | Article |
| id | upm-24776 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:41:54Z |
| publishDate | 2011 |
| publisher | Electrochemical Science Group |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-247762015-10-16T07:30:38Z http://psasir.upm.edu.my/id/eprint/24776/ Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. Mohammed Zidan, Tan, Wee Tee Abdullah, Abdul Halim Zainal, Zulkarnain Goh, Joo Kheng Nanoparticles of bismuth oxide (Bi2O3) have been mechanically attached on the surface of a glassy carbon electrode. Electrochemical performance of nanoparticles of Bi2O3/GC modified electrode shows stable response with enhanced selectivity and sensitivity. Voltammetric determination of the oxidation of paracetamol in 0.1 M KH2PO4 electrolyte solution by solid phase voltammetry has shown electrocatalyzing effect. Observation revealed a high peak toward the origin of paracetamol oxidation current, which showed 2.0 times increment as compared to bare GC electrode. The sensitivity under conditions of cyclic voltammetry is significantly dependent on pH and temperature. The variation of scan rate study shows that the system undergoes diffusion-controlled process. Calibration plot reveals linearity from the range 5.0 × 10-7 to 1.5 × 10-3M with a correlation coefficient of 0.994. The detection limit was estimated to be 2.0 × 10-7 M. Based on interference studies, most amino acids have negligibly affected the current response of paracetamol. Practically, nanoparticles of bismuth oxide (Bi2O3) modified GC electrode could be used for the determination of parecetamol in blood plasma samples. Electrochemical Science Group 2011-02 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24776/1/Electrochemical%20oxidation%20of%20paracetamol%20mediated%20by%20nanoparticles%20bismuth%20oxide%20modified%20glassy%20carbon%20electrode.pdf Mohammed Zidan, and Tan, Wee Tee and Abdullah, Abdul Halim and Zainal, Zulkarnain and Goh, Joo Kheng (2011) Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. International Journal of Electrochemical Science, 6 (2). pp. 279-288. ISSN 1452-3981 http://www.electrochemsci.org/ English |
| spellingShingle | Mohammed Zidan, Tan, Wee Tee Abdullah, Abdul Halim Zainal, Zulkarnain Goh, Joo Kheng Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title | Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title_full | Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title_fullStr | Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title_full_unstemmed | Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title_short | Electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| title_sort | electrochemical oxidation of paracetamol mediated by nanoparticles bismuth oxide modified glassy carbon electrode. |
| url | http://psasir.upm.edu.my/id/eprint/24776/ http://psasir.upm.edu.my/id/eprint/24776/ http://psasir.upm.edu.my/id/eprint/24776/1/Electrochemical%20oxidation%20of%20paracetamol%20mediated%20by%20nanoparticles%20bismuth%20oxide%20modified%20glassy%20carbon%20electrode.pdf |