Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats.
It has been reported that a diet enriched in fructose would present animal models used to emulate diabetes mellitus type 2 in human. This study aimed to examine the effect of high fructose induction on the blood glucose, C-reactive protein, interleukin-6, interleukin-4 and body weight among high fru...
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| Format: | Article |
| Language: | English English |
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Asian Network for Scientific Information
2012
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24647/ http://psasir.upm.edu.my/id/eprint/24647/1/Evaluating%20of%20high%20fructose%20diet%20to%20induce%20hyperglycemia%20and%20its%20inflammatory%20complication%20in%20rats.pdf |
| _version_ | 1848845093107138560 |
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| author | Zafershani, Aida Abd Mutalib, Mohd Sokhini Khaza'ai, Huzwah |
| author_facet | Zafershani, Aida Abd Mutalib, Mohd Sokhini Khaza'ai, Huzwah |
| author_sort | Zafershani, Aida |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | It has been reported that a diet enriched in fructose would present animal models used to emulate diabetes mellitus type 2 in human. This study aimed to examine the effect of high fructose induction on the blood glucose, C-reactive protein, interleukin-6, interleukin-4 and body weight among high fructose diet-induced rats. The HFD was induced through drinking water in 21% (w/v) concentration among male Sprague-Dawley rats. The high fructose diet administration was unable to induce hyperglycemia, hypertriglyceridemia or any classic inflammatory markers. Also, no histological inflammation was observed. It was concluded that healthy Sprague-Dawley rats fed high fructose diet for 2.5 months could not develop signs of diabetes mellitus type 2. |
| first_indexed | 2025-11-15T08:41:20Z |
| format | Article |
| id | upm-24647 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:41:20Z |
| publishDate | 2012 |
| publisher | Asian Network for Scientific Information |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-246472015-11-18T02:48:45Z http://psasir.upm.edu.my/id/eprint/24647/ Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. Zafershani, Aida Abd Mutalib, Mohd Sokhini Khaza'ai, Huzwah It has been reported that a diet enriched in fructose would present animal models used to emulate diabetes mellitus type 2 in human. This study aimed to examine the effect of high fructose induction on the blood glucose, C-reactive protein, interleukin-6, interleukin-4 and body weight among high fructose diet-induced rats. The HFD was induced through drinking water in 21% (w/v) concentration among male Sprague-Dawley rats. The high fructose diet administration was unable to induce hyperglycemia, hypertriglyceridemia or any classic inflammatory markers. Also, no histological inflammation was observed. It was concluded that healthy Sprague-Dawley rats fed high fructose diet for 2.5 months could not develop signs of diabetes mellitus type 2. Asian Network for Scientific Information 2012 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24647/1/Evaluating%20of%20high%20fructose%20diet%20to%20induce%20hyperglycemia%20and%20its%20inflammatory%20complication%20in%20rats.pdf Zafershani, Aida and Abd Mutalib, Mohd Sokhini and Khaza'ai, Huzwah (2012) Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. Pakistan Journal of Nutrition, 1 (11). pp. 21-26. ISSN 1680-5194; ESSN:1994-7984 http://www.ansinet.com/ English |
| spellingShingle | Zafershani, Aida Abd Mutalib, Mohd Sokhini Khaza'ai, Huzwah Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title | Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title_full | Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title_fullStr | Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title_full_unstemmed | Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title_short | Evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| title_sort | evaluating of high fructose diet to induce hyperglycemia and its inflammatory complication in rats. |
| url | http://psasir.upm.edu.my/id/eprint/24647/ http://psasir.upm.edu.my/id/eprint/24647/ http://psasir.upm.edu.my/id/eprint/24647/1/Evaluating%20of%20high%20fructose%20diet%20to%20induce%20hyperglycemia%20and%20its%20inflammatory%20complication%20in%20rats.pdf |