Subacute effects of edible film from modified sago starch in rats.

The effects of edible film from modified sago starch were determined on female Sprague-Dawley rats where the aim was to develop a basic guideline for safe use of edible films as food packaging. Rats were fed with 2 g kg-1 (low dose) and 5 g kg-1 (high dose) of body weight edible film for 28 days an...

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Main Authors: Hosni, Hanisa, Adzaly, Noor Zainah, S., Ahmad Tarmizi, W. M., Wan Abd Aziz, Somchit, Muhammad Nazrul
Format: Article
Language:English
English
Published: Academic Journals 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24584/
http://psasir.upm.edu.my/id/eprint/24584/1/Subacute%20effects%20of%20edible%20film%20from%20modified%20sago%20starch%20in%20rats.pdf
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author Hosni, Hanisa
Adzaly, Noor Zainah
S., Ahmad Tarmizi
W. M., Wan Abd Aziz
Somchit, Muhammad Nazrul
author_facet Hosni, Hanisa
Adzaly, Noor Zainah
S., Ahmad Tarmizi
W. M., Wan Abd Aziz
Somchit, Muhammad Nazrul
author_sort Hosni, Hanisa
building UPM Institutional Repository
collection Online Access
description The effects of edible film from modified sago starch were determined on female Sprague-Dawley rats where the aim was to develop a basic guideline for safe use of edible films as food packaging. Rats were fed with 2 g kg-1 (low dose) and 5 g kg-1 (high dose) of body weight edible film for 28 days and the control rats only received normal rat pellet. The study showed that repeated administration of high dose edible film to rats did produce significant change in the liver function (total bilirubin) and renal function parameters (creatinine). Other metabolic parameters tested were: aspartate transaminase, alanine transaminase and alkaline phosphatase, blood lipid profile; cholesterol, high-density lipoprotein, low-density lipoprotein and triglyceride, total protein and glucose concentrations, however, they were not significantly changed with respect to control animals. In conclusion, edible film from modified sago starch at 2 g kg-1 is less likely to develop toxicity as observed in the sub-acute toxicity study.
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language English
English
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publishDate 2011
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spelling upm-245842015-09-14T07:37:53Z http://psasir.upm.edu.my/id/eprint/24584/ Subacute effects of edible film from modified sago starch in rats. Hosni, Hanisa Adzaly, Noor Zainah S., Ahmad Tarmizi W. M., Wan Abd Aziz Somchit, Muhammad Nazrul The effects of edible film from modified sago starch were determined on female Sprague-Dawley rats where the aim was to develop a basic guideline for safe use of edible films as food packaging. Rats were fed with 2 g kg-1 (low dose) and 5 g kg-1 (high dose) of body weight edible film for 28 days and the control rats only received normal rat pellet. The study showed that repeated administration of high dose edible film to rats did produce significant change in the liver function (total bilirubin) and renal function parameters (creatinine). Other metabolic parameters tested were: aspartate transaminase, alanine transaminase and alkaline phosphatase, blood lipid profile; cholesterol, high-density lipoprotein, low-density lipoprotein and triglyceride, total protein and glucose concentrations, however, they were not significantly changed with respect to control animals. In conclusion, edible film from modified sago starch at 2 g kg-1 is less likely to develop toxicity as observed in the sub-acute toxicity study. Academic Journals 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24584/1/Subacute%20effects%20of%20edible%20film%20from%20modified%20sago%20starch%20in%20rats.pdf Hosni, Hanisa and Adzaly, Noor Zainah and S., Ahmad Tarmizi and W. M., Wan Abd Aziz and Somchit, Muhammad Nazrul (2011) Subacute effects of edible film from modified sago starch in rats. American Journal of Food Technology, 6 (8). pp. 695-700. ISSN 1557-4571; ESSN: 1557-458X http://scialert.net/jindex.php?issn=1557-4571 10.3923/ajft.2011.695.700 English
spellingShingle Hosni, Hanisa
Adzaly, Noor Zainah
S., Ahmad Tarmizi
W. M., Wan Abd Aziz
Somchit, Muhammad Nazrul
Subacute effects of edible film from modified sago starch in rats.
title Subacute effects of edible film from modified sago starch in rats.
title_full Subacute effects of edible film from modified sago starch in rats.
title_fullStr Subacute effects of edible film from modified sago starch in rats.
title_full_unstemmed Subacute effects of edible film from modified sago starch in rats.
title_short Subacute effects of edible film from modified sago starch in rats.
title_sort subacute effects of edible film from modified sago starch in rats.
url http://psasir.upm.edu.my/id/eprint/24584/
http://psasir.upm.edu.my/id/eprint/24584/
http://psasir.upm.edu.my/id/eprint/24584/
http://psasir.upm.edu.my/id/eprint/24584/1/Subacute%20effects%20of%20edible%20film%20from%20modified%20sago%20starch%20in%20rats.pdf