Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.

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Possible participation of nitric oxide/cyclic guanosine monophosphate/protein kinase C/ATP-sensitive K + channels pathway in the systemic antinociception of flavokawin B.

The possible mechanisms of action in the antinociceptive activity induced by systemic administration (intraperitoneal, i.p.) of flavokawin B (FKB) were analysed using chemical models of nociception in mice. It was demonstrated that i.p. administration of FKB to the mice at 0.3, 1.0, 3.0 and 10 mg/k...

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Bibliographic Details
Main Authors:	Tengku Mohamad, Tengku Azam Shah, Akhtar, Muhammad Nadeem, Khalivulla, Shaik Ibrahim, Perimal, Enoch Kumar, Khalid, Mohamed Hanief, Hui, Ming Ong, Zareen, Seema, Omar Farouk, Ahmad Akira, Israf Ali, Daud Ahmad, Lajis, Md. Nordin, Sulaiman, Mohd Roslan
Format:	Article
Language:	English English
Published:	Wiley 2011
Online Access:	http://psasir.upm.edu.my/id/eprint/24557/ http://psasir.upm.edu.my/id/eprint/24557/1/Possible%20participation%20of%20nitric%20oxide.pdf

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