Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study.
This study aimed to quantify the amount of change in Standardised Uptake Values (SUVs) of PET/CT images by simulating the set-up as closely as possible to the actual patient scanning. The experiments were conducted using an anthropomorphic phantom, which contained an amount of radioactivity in the f...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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Springer Verlag
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24536/ http://psasir.upm.edu.my/id/eprint/24536/1/Quantifying%20the%20effects%20of%20iodine%20contrast%20media%20on%20standardised%20uptake%20values%20of%20FDG%20PET.pdf |
| _version_ | 1848845062924926976 |
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| author | Abdul Razak, Hairil Rashmizal Nordin, Abdul Jalil Ackerly, Trevor Van Every, Bruce Martin, Ruth Geso, Moshi |
| author_facet | Abdul Razak, Hairil Rashmizal Nordin, Abdul Jalil Ackerly, Trevor Van Every, Bruce Martin, Ruth Geso, Moshi |
| author_sort | Abdul Razak, Hairil Rashmizal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | This study aimed to quantify the amount of change in Standardised Uptake Values (SUVs) of PET/CT images by simulating the set-up as closely as possible to the actual patient scanning. The experiments were conducted using an anthropomorphic phantom, which contained an amount of radioactivity in the form of Fluorodeoxyglucose (FDG) in a primary plastic test tube and one litre saline bags, including the insertion of bony structures and another two test tubes containing different concentrations of iodine contrast media. Standard scanning protocols were employed for the PET/CT image acquisition. The highest absolute differences in the SUVmax and SUVmean values of the saline bags were found to be about 0.2 and 0.4, respectively. The primary test tube showed the largest change of 1.5 in both SUVs; SUV max and SUVmean. However, none of these changes were found to be statistically significant. The clinical literature also contains no evidence to suggest that the changes of this magnitude would change the final diagnosis. Based on these preliminary data, we propose that iodine contrast media can be used during the CT scan of PET/CT imaging, without significantly affecting the diagnostic quality of this integrated imaging modality. |
| first_indexed | 2025-11-15T08:40:51Z |
| format | Article |
| id | upm-24536 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:40:51Z |
| publishDate | 2011 |
| publisher | Springer Verlag |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-245362015-09-29T07:42:33Z http://psasir.upm.edu.my/id/eprint/24536/ Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. Abdul Razak, Hairil Rashmizal Nordin, Abdul Jalil Ackerly, Trevor Van Every, Bruce Martin, Ruth Geso, Moshi This study aimed to quantify the amount of change in Standardised Uptake Values (SUVs) of PET/CT images by simulating the set-up as closely as possible to the actual patient scanning. The experiments were conducted using an anthropomorphic phantom, which contained an amount of radioactivity in the form of Fluorodeoxyglucose (FDG) in a primary plastic test tube and one litre saline bags, including the insertion of bony structures and another two test tubes containing different concentrations of iodine contrast media. Standard scanning protocols were employed for the PET/CT image acquisition. The highest absolute differences in the SUVmax and SUVmean values of the saline bags were found to be about 0.2 and 0.4, respectively. The primary test tube showed the largest change of 1.5 in both SUVs; SUV max and SUVmean. However, none of these changes were found to be statistically significant. The clinical literature also contains no evidence to suggest that the changes of this magnitude would change the final diagnosis. Based on these preliminary data, we propose that iodine contrast media can be used during the CT scan of PET/CT imaging, without significantly affecting the diagnostic quality of this integrated imaging modality. Springer Verlag 2011-09 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24536/1/Quantifying%20the%20effects%20of%20iodine%20contrast%20media%20on%20standardised%20uptake%20values%20of%20FDG%20PET.pdf Abdul Razak, Hairil Rashmizal and Nordin, Abdul Jalil and Ackerly, Trevor and Van Every, Bruce and Martin, Ruth and Geso, Moshi (2011) Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. Australasian Physical & Engineering Sciences in Medicine, 34 (3). pp. 367-374. ISSN 0158-9938; ESSN: 1879-5447 10.1007/s13246-011-0088-y English |
| spellingShingle | Abdul Razak, Hairil Rashmizal Nordin, Abdul Jalil Ackerly, Trevor Van Every, Bruce Martin, Ruth Geso, Moshi Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title | Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title_full | Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title_fullStr | Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title_full_unstemmed | Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title_short | Quantifying the effects of iodine contrast media on standardised uptake values of FDG PET/CT images : an anthropomorphic phantom study. |
| title_sort | quantifying the effects of iodine contrast media on standardised uptake values of fdg pet/ct images : an anthropomorphic phantom study. |
| url | http://psasir.upm.edu.my/id/eprint/24536/ http://psasir.upm.edu.my/id/eprint/24536/ http://psasir.upm.edu.my/id/eprint/24536/1/Quantifying%20the%20effects%20of%20iodine%20contrast%20media%20on%20standardised%20uptake%20values%20of%20FDG%20PET.pdf |