Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria
Jatropha curcas is a drought-resistant tree belonging to the family Euphorbiaceae. The latex of J. curcas has been traditionally used to heal wounds and has reported anti-coagulant and coagulant properties. In this study, fractions of the methanol, aqueous, ethyl acetate and hexane extracts from the...
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Academic Journals
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24531/ http://psasir.upm.edu.my/id/eprint/24531/1/24531.pdf |
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| author | Suhaili, Zarizal Yeo, Chew Chieng Yasin, Hasrif Nurhana Badaludin, Nor Afiza Zakaria, Zainul Amiruddin |
| author_facet | Suhaili, Zarizal Yeo, Chew Chieng Yasin, Hasrif Nurhana Badaludin, Nor Afiza Zakaria, Zainul Amiruddin |
| author_sort | Suhaili, Zarizal |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Jatropha curcas is a drought-resistant tree belonging to the family Euphorbiaceae. The latex of J. curcas has been traditionally used to heal wounds and has reported anti-coagulant and coagulant properties. In this study, fractions of the methanol, aqueous, ethyl acetate and hexane extracts from the Jatropha latex were tested for antibacterial properties against nine different human pathogenic bacteria, namely three different isolates of Staphylococcus aureus (one methicillin-resistant strain MRSA ATCC 33591, and two methicillin-sensitive strains MSSA ATCC 29213 and ATCC 25174), Salmonella enterica serovar typhi, Streptococcus agalactiae, Serratia marcescens, Klebsiella pneumoniae, Enterococcus faecalis (E248), Escherichia coli (ATCC 35218), Listeria monocytogenes (IMR L10), and Morganella morgenii (IMR MM99). The zones of inhibition produced by the extracts using an agar well diffusion method against the test microorganisms were found to range from 2.7 to 29 mm. The methanol extract was found to be the most effective extract with MIC values ranging from 0.39 mg/ml for methicillin-sensitive S. aureus and 6.25 mg/ml for S. marcescens. Hexane extracts did not show any antibacterial activity. Phytochemical screening of the J. curcas latex indicated the presence of saponins and tannins which are known to have antibacterial properties. |
| first_indexed | 2025-11-15T08:40:50Z |
| format | Article |
| id | upm-24531 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:40:50Z |
| publishDate | 2011 |
| publisher | Academic Journals |
| recordtype | eprints |
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| spelling | upm-245312017-11-17T08:30:19Z http://psasir.upm.edu.my/id/eprint/24531/ Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria Suhaili, Zarizal Yeo, Chew Chieng Yasin, Hasrif Nurhana Badaludin, Nor Afiza Zakaria, Zainul Amiruddin Jatropha curcas is a drought-resistant tree belonging to the family Euphorbiaceae. The latex of J. curcas has been traditionally used to heal wounds and has reported anti-coagulant and coagulant properties. In this study, fractions of the methanol, aqueous, ethyl acetate and hexane extracts from the Jatropha latex were tested for antibacterial properties against nine different human pathogenic bacteria, namely three different isolates of Staphylococcus aureus (one methicillin-resistant strain MRSA ATCC 33591, and two methicillin-sensitive strains MSSA ATCC 29213 and ATCC 25174), Salmonella enterica serovar typhi, Streptococcus agalactiae, Serratia marcescens, Klebsiella pneumoniae, Enterococcus faecalis (E248), Escherichia coli (ATCC 35218), Listeria monocytogenes (IMR L10), and Morganella morgenii (IMR MM99). The zones of inhibition produced by the extracts using an agar well diffusion method against the test microorganisms were found to range from 2.7 to 29 mm. The methanol extract was found to be the most effective extract with MIC values ranging from 0.39 mg/ml for methicillin-sensitive S. aureus and 6.25 mg/ml for S. marcescens. Hexane extracts did not show any antibacterial activity. Phytochemical screening of the J. curcas latex indicated the presence of saponins and tannins which are known to have antibacterial properties. Academic Journals 2011-12-09 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24531/1/24531.pdf Suhaili, Zarizal and Yeo, Chew Chieng and Yasin, Hasrif Nurhana and Badaludin, Nor Afiza and Zakaria, Zainul Amiruddin (2011) Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria. African Journal of Microbiology Research, 5 (29). art. no. 842DFA222025. pp. 5147-5154. ISSN 1996-0808 http://www.academicjournals.org/journal/AJMR/article-abstract/842DFA222025 10.5897/AJMR11.663 |
| spellingShingle | Suhaili, Zarizal Yeo, Chew Chieng Yasin, Hasrif Nurhana Badaludin, Nor Afiza Zakaria, Zainul Amiruddin Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title | Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title_full | Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title_fullStr | Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title_full_unstemmed | Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title_short | Antibacterial profile of Jatropha curcas latex extracts against selected human pathogenic bacteria |
| title_sort | antibacterial profile of jatropha curcas latex extracts against selected human pathogenic bacteria |
| url | http://psasir.upm.edu.my/id/eprint/24531/ http://psasir.upm.edu.my/id/eprint/24531/ http://psasir.upm.edu.my/id/eprint/24531/ http://psasir.upm.edu.my/id/eprint/24531/1/24531.pdf |