$Thymoquinone rich fraction from Nigella sativa and thymoquinone are cytotoxic towards colon and leukemic carcinoma cell lines.$
QR Code

QR Code

Thymoquinone rich fraction from Nigella sativa and thymoquinone are cytotoxic towards colon and leukemic carcinoma cell lines.

Nigella sativa has been used for centuries in Asia, Middle East and Africa to promote health and fight diseases. In this study, the anti-cancer effects of thymoquinone rich fraction (TQRF) extracted from N. sativa seeds using supercritical fluid extraction (SFE) system and commercially available thy...

Full description

Bibliographic Details
Main Authors:	Ismail, Norsharina, Ismail, Maznah, Al-Absi, Aied, Al-Naqeeb, Ghanya
Format:	Article
Language:	English English
Published:	Academic Journals 2011
Online Access:	http://psasir.upm.edu.my/id/eprint/24493/ http://psasir.upm.edu.my/id/eprint/24493/1/Thymoquinone%20rich%20fraction%20from%20Nigella%20sativa%20and%20thymoquinone%20are%20cytotoxic%20towards%20colon%20and%20leukemic%20carcinoma%20cell%20lines.pdf

Similar Items

Extraction, Gene Regulation and Hypocholesterolemic Effects, and Antioxidative Activity of Thymoquinone Rich Fraction and Thymoquinone from Nigella Sativa (pdf incomplete)
by: Al-Naqeeb, Ghanya Naji
Published: (2009)

Cytotoxicity of Thymoquinone (TQ) from Nigella sativa towards human cervical carcinoma cells (HeLa).
by: Saiful Yazan, Latifah, et al.
Published: (2009)

Regulation of Apolipoprotein A-1 and Apolipoprotein B100 Genes by Thymoquinone Rich Fraction and Thymoquinone in HEPG2 Cells.
by: Al Naqeeb, Ghanya, et al.
Published: (2009)

Nigella sativa thymoquinone-rich fraction greatly improves plasma antioxidant capacity and expression of antioxidant genes in hypercholesterolemic rats.
by: Ismail , Maznah, et al.
Published: (2010)

Extraction of fixed oil and thymoquinone rich fractions (TQRF)
by: Ismail, Maznah, et al.
Published: (2014)

Neuroprotective effects of thymoquinone-rich fraction and thymoquinone nanoemulsions in sporadic alzheimer’s disease rat model
by: Ismail, Norsharina
Published: (2019)

Extraction of pharmacologically active thymoquinone in nigella sativa L.
by: Nazeri, Nasaruddin
Published: (2006)

Effects of thymoquinone rich fraction and thymoquinone on plasma lipoprotein levels and hepatic low density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase genes expression.
by: Al-Naqeep, Ghanya, et al.
Published: (2009)

Regulation of low-density lipoprotein receptor and 3-hydroxy-3-methylglutaryl coenzyme A reductase gene expression by thymoquinone-rich fraction and thymoquinone in HepG2 cells
by: Al-Naqeep, Ghanya, et al.
Published: (2009)

Cardioprotactive effects of nutraceuticals isolated from Nigella sativa seeds.
by: Ismail, Maznah, et al.
Published: (2012)

The chemopreventive effects of Nigella sativa extract and Thymoquinone in a paternal toxicity study
by: Abdul Samat, Nadia Hanis, et al.
Published: (2015)

The potential of nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

Potential effects of Nigella sativa and thymoquinone on the foetal development of cyclophosphamide-treated male mice
by: Abdul Rahman, Suzanah, et al.
Published: (2016)

The potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure
by: Abdul Samat, Nadia Hanis, et al.
Published: (2016)

Modulation of hydrogen peroxide-induced oxidative stress in human neuronal cells by Thymoquinone-rich fraction and Thymoquinone via transcriptomic regulation of antioxidant and apoptotic signaling genes
by: Ismail, Norsharina, et al.
Published: (2016)

Evaluation of the anti-cancer potential of Nigella sativa and its bioactive constituents thymoquinone and alpha-hederin
by: Zafar, Mashal
Published: (2024)

Anti-cancer activities of Thymoquinone, constituents of Nigella sativa against oral cancer cell lines
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2010)

Apoptotic activities of thymoquinone, an active ingredient of black seed (nigella sativa), in cervical cancer cell lines
by: Arief Ichwan, Solachuddin Jauhari, et al.
Published: (2014)

Nutrient Composition and Hypocholesterolemic Effect of black Seeds (Nigella Sativa L.) and its Oil
by: Al-Naqeeb, Ghanya Naji
Published: (2005)

Investigating the potential of Nigella Sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Investigating the potential of Nigella sativa and thymoquinone in salvaging the embryo from effects of toxic paternal exposure to cyclophosphamide
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Antioxidant property, thymoquinone content and chemical characteristics of different extracts from Nigella sativa L. seeds
by: Solati, Zeinab, et al.
Published: (2014)

Study on the potential toxicity of a thymoquinone-rich fraction nanoemulsion in Sprague Dawley rats
by: Tubesha, Zaki, et al.
Published: (2013)

Thymoquinone from Nigella sativa was more potent than cisplatin in eliminating of SiHa cells via apoptosis with down-regulation of Bcl-2 protein
by: Ng, Wei Keat, et al.
Published: (2011)

Fatty acid profile, α-tocopherol content and total antioxidant activity of oil extracted from Nigella sativa seeds.
by: Al-Naqeeb, Ghanya Naji, et al.
Published: (2009)

Cytotoxicity of thymoquinone and thymoquinone-loaded nanostrustured lipid carrier on cervical cancer cells (SiHa and HeLa)
by: Ng, Wei Keat
Published: (2015)

Prophylactic effects of Nigella sativa extract and thymoquinone against cyclophosphamide-induced sperm head abnormalities and chromatin instability in mice
by: Abdul Rahman, Suzanah, et al.
Published: (2017)

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn
by: Shanmugam, M., et al.
Published: (2018)

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn
by: Shanmugam, M., et al.
Published: (2017)

Antioxidant activity and phenolic content of phenolic rich fractions obtained from black cumin (Nigella sativa) seedcake.
by: Mariod, Abdalbasit Adam, et al.
Published: (2009)

Effects of thymoquinone and thymoquinone-loaded nanostructured lipid carrier on hepatocellular carcinoma cell models, Hep3B and HepG2
by: Haron, Aminah Suhaila
Published: (2017)

Cytotoxic and apoptotic effects of curcumin and thymoquinone on HSC-2 cell line
by: Saleem, Khadeeja
Published: (2021)

Effect of thymoquinone and thymoquinone-loaded nanostructured lipid carrier in in vitro wound healing model
by: Alexander, Henna Roshini
Published: (2019)

5-fluorouracil in combination with calcium carbonate nanoparticles loaded with antioxidant thymoquinone against colon cancer: synergistically therapeutic potential and underlying molecular mechanism
by: Deng, Xi, et al.
Published: (2024)

Development, characterization and anti-diabetic properties of thymoquinone rich fraction nanoemulsion obtained from black cumin
by: Tubesha, Zaki A.H.
Published: (2013)

Thymoquinone prevents β-amyloid neurotoxicity in primary cultured cerebellar granule neurons
by: Ismail, Norsharina, et al.
Published: (2013)

Characterization and stability evaluation of thymoquinone nanoemulsions prepared by high-pressure homogenization
by: Tubesha, Zaki, et al.
Published: (2013)

Thymoquinone content in marketed black seed oil in Malaysia
by: Alkhatib, Hamzeh, et al.
Published: (2020)

Evaluating the immunopathological effects of nigella sativa oil and its major component, thymoquinone in a streptozotocin-induces type1 diabetes rat model / Afaf Jamal Ali Hmza
by: Ali Hmza, Afaf Jamal
Published: (2013)

Thymoquinone: Potential cure for inflammatory disorders and cancer
by: Woo, C., et al.
Published: (2012)