Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk.
Quantitation of isoflavones in humans is important to establish the benefits of these compounds to the populations. Urinary isoflavones are frequently used as a biomarker of isoflavone bioavailability from food or supplement since urine contains 100-fold higher concentrations of isoflavones. The obj...
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| Format: | Article |
| Language: | English English |
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Informa Healthcare
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24465/ http://psasir.upm.edu.my/id/eprint/24465/1/Apparent%20bioavailability%20of%20isoflavones%20in%20urinary%20excretions%20of%20postmenopausal%20Malay%20women%20consuming%20tempeh%20compared%20with%20milk.pdf |
| _version_ | 1848845044608401408 |
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| author | Haron, Hasnah Ismail, Amin Shahar, Suzana Azlan, Azrina Loh, Su Peng |
| author_facet | Haron, Hasnah Ismail, Amin Shahar, Suzana Azlan, Azrina Loh, Su Peng |
| author_sort | Haron, Hasnah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Quantitation of isoflavones in humans is important to establish the benefits of these compounds to the populations. Urinary isoflavones are frequently used as a biomarker of isoflavone bioavailability from food or supplement since urine contains 100-fold higher concentrations of isoflavones. The objective of the present study was to determine and compare the urinary excretions of daidzein (DA), genistein (GE) and equol (EQ) in postmenopausal Malay women following the consumption of tempeh and milk in a calcium absorption study and to test the hypothesis that the excretion of isoflavones following consumption of tempeh maybe higher compared with milk. The amounts of DA (47.06 ± 4.18 μmol/h), GE (33.27 ± 3.71 μmol/h) and EQ (24.35 ± 4.34 μmol/h) excreted in urine following tempeh consumption were significantly higher (P < 0.05) compared with those in milk (3.51 ± 0.62 μmol/h DA, 2.79 ± 0.35 μmol/h GE and 0 μmol/h EQ). Almost all studied postmenopausal Malay women were able to excrete EQ following consumption of 240 g tempeh but only one subject can be classified as an equol producer. We concluded that most postmenopausal Malay women excreted DA, GE and EQ in their urine following tempeh consumption and the amount of the excreted isoflavones were higher compared with those in milk. However, further studies are needed to determine whether longer periods of time are required to capture EQ producers. |
| first_indexed | 2025-11-15T08:40:34Z |
| format | Article |
| id | upm-24465 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:40:34Z |
| publishDate | 2011 |
| publisher | Informa Healthcare |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-244652015-09-14T01:33:59Z http://psasir.upm.edu.my/id/eprint/24465/ Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. Haron, Hasnah Ismail, Amin Shahar, Suzana Azlan, Azrina Loh, Su Peng Quantitation of isoflavones in humans is important to establish the benefits of these compounds to the populations. Urinary isoflavones are frequently used as a biomarker of isoflavone bioavailability from food or supplement since urine contains 100-fold higher concentrations of isoflavones. The objective of the present study was to determine and compare the urinary excretions of daidzein (DA), genistein (GE) and equol (EQ) in postmenopausal Malay women following the consumption of tempeh and milk in a calcium absorption study and to test the hypothesis that the excretion of isoflavones following consumption of tempeh maybe higher compared with milk. The amounts of DA (47.06 ± 4.18 μmol/h), GE (33.27 ± 3.71 μmol/h) and EQ (24.35 ± 4.34 μmol/h) excreted in urine following tempeh consumption were significantly higher (P < 0.05) compared with those in milk (3.51 ± 0.62 μmol/h DA, 2.79 ± 0.35 μmol/h GE and 0 μmol/h EQ). Almost all studied postmenopausal Malay women were able to excrete EQ following consumption of 240 g tempeh but only one subject can be classified as an equol producer. We concluded that most postmenopausal Malay women excreted DA, GE and EQ in their urine following tempeh consumption and the amount of the excreted isoflavones were higher compared with those in milk. However, further studies are needed to determine whether longer periods of time are required to capture EQ producers. Informa Healthcare 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24465/1/Apparent%20bioavailability%20of%20isoflavones%20in%20urinary%20excretions%20of%20postmenopausal%20Malay%20women%20consuming%20tempeh%20compared%20with%20milk.pdf Haron, Hasnah and Ismail, Amin and Shahar, Suzana and Azlan, Azrina and Loh, Su Peng (2011) Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. International Journal of Food Sciences and Nutrition, 62 (6). pp. 642-650. ISSN 0963-7486; ESSN: 1465-3478 http://informahealthcare.com/ijf 10.3109/09637486.2011.570742 English |
| spellingShingle | Haron, Hasnah Ismail, Amin Shahar, Suzana Azlan, Azrina Loh, Su Peng Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title | Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title_full | Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title_fullStr | Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title_full_unstemmed | Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title_short | Apparent bioavailability of isoflavones in urinary excretions of postmenopausal Malay women consuming tempeh compared with milk. |
| title_sort | apparent bioavailability of isoflavones in urinary excretions of postmenopausal malay women consuming tempeh compared with milk. |
| url | http://psasir.upm.edu.my/id/eprint/24465/ http://psasir.upm.edu.my/id/eprint/24465/ http://psasir.upm.edu.my/id/eprint/24465/ http://psasir.upm.edu.my/id/eprint/24465/1/Apparent%20bioavailability%20of%20isoflavones%20in%20urinary%20excretions%20of%20postmenopausal%20Malay%20women%20consuming%20tempeh%20compared%20with%20milk.pdf |