Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

QR Code

Measurement methods and accuracy in copy number variation: failure to replicate associations of beta-defensin copy number with Crohn's disease.

The copy number variation in beta-defensin genes on human chromosome 8 has been proposed to underlie susceptibility to inflammatory disorders, but presents considerable challenges for accurate typing on the scale required for adequately powered case-control studies. In this work, we have used accura...

Full description

Bibliographic Details
Main Authors:	Aldhous, Marian C., Abu Bakar @ Jamaludin, Suhaili, Prescott, Natalie J., Palla, Raquel, Soo, Kimberley, Mansfield, John C., Mathew, Christopher G., Satsangi, Jack, Armour, A. L.
Format:	Article
Language:	English English
Published:	Oxford University Press 2010
Online Access:	http://psasir.upm.edu.my/id/eprint/24407/ http://psasir.upm.edu.my/id/eprint/24407/1/Measurement%20methods%20and%20accuracy%20in%20copy%20number%20variation.pdf

Similar Items

Generation of diversity at the human beta-defensin copy number
by: Abu Bakar, Suhaili
Published: (2010)

Human beta-defensin gene copy number variation and consequences in disease and evolution
by: Pala, Raquel Rodrigues
Published: (2012)

Characterization of the alpha defensin copy number variation in humans
by: Khan, Fayeza Fatima
Published: (2012)

Quantification of beta-defensin copy number variable genes in relation to inflammation in diabetic patients
by: Yusoff, Maryam Jamielah
Published: (2015)

Accurate measurement of gene copy number for human alpha-defensin DEFA1A3
by: Khan, Fayeza F., et al.
Published: (2013)

A Preliminary Study On The Distribution Of Beta Defensins Copy Number Variable Gene In Different Ethnics Of Sarawak, Malaysian Borneo
by: Zahirunisa, Abd Rahim, et al.
Published: (2017)

A preliminary study on the distribution of beta defensins copy number variable gene in different ethnics of Sarawak, Malaysian Borneo
by: Abd Rahim, Zahirunisa, et al.
Published: (2017)

Low alpha-defensin gene copy number increases the risk for IgA nephropathy and renal dysfunction
by: Ai, Zhen, et al.
Published: (2016)

Descriptive study on the origin and evolution of beta- defensins copy number variable gene using multigenerational family pedigrees
by: Musa, Nurul Azmah
Published: (2019)

Quantification of beta-defensins (DEFB) gene copy number variations in relation to inflammation in type 2 diabetes mellitus and diabetic nephropathy patients
by: Yusoff, Maryam Jamielah, et al.
Published: (2020)

CCL3L1 copy number and susceptibility to malaria
by: Carpenter, Danielle, et al.
Published: (2012)

Allelic structures and mechanisms of copy number change at the human DEFA1A3 copy number variable locus
by: Black, Holly Ann
Published: (2014)

Copy number variation of the beta-defensin genes in Europeans: no supporting evidence for association with lung function, chronic obstructive pulmonary disease or asthma
by: Ahuja, Sunil K., et al.
Published: (2014)

Measuring human salivary amylase copy number variation
by: Dhar, Sugandha
Published: (2010)

A quantitative PCR approach to determine gene copy number
by: Solomon, P., et al.
Published: (2008)

Association of beta-defensin gene copy number variation with CD4 count and viral load among Malaysian ethnics hiv patients after HAART initiation
by: Achim, Nurfarahin Hanini
Published: (2020)

CCL3L1 copy number, CCR5 genotype and susceptibility to tuberculosis
by: Carpenter, Danielle, et al.
Published: (2014)

Copy Number Variation Analysis of 100 Twin Pairs Enriched for Neurodevelopmental Disorders
by: Stamouli, S., et al.
Published: (2018)

Copy number variation of human AMY1 is a minor contributor to variation in salivary amylase expression and activity
by: Carpenter, Danielle, et al.
Published: (2017)

Inferring mechanisms of copy number change from haplotype structures at the human DEFA1A3 locus
by: Black, Holly A., et al.
Published: (2014)

Copy number variation of CCL3L1 among three major ethnic groups in Malaysia
by: Jamaluddin, Jalilah, et al.
Published: (2020)

Copy number variations in Friesian horses and genetic risk factors for insect bite hypersensitivity
by: Schurink, Anouk, et al.
Published: (2018)

Copy number variations of Orang Asli’ (Negrito) from Peninsular Malaysia / Siti Shuhada Mokhtar
by: Mokhtar, Siti Shuhada
Published: (2015)

To copy or not to copy: an evaluation of English undergraduate majors’ awareness of plagiarism
by: Lotfie, Maskanah Mohammad
Published: (2012)

The identification of copy number variation of CNV esv27061 among young adults with hypertension: preliminary findings
by: Shaik Alaudeen, Siti Radziah, et al.
Published: (2017)

Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans
by: Blackburn, A., et al.
Published: (2015)

Population-specific profiling of CCL3L1 copy number of the three major ethnic groups in Malaysia and the implication on HIV susceptibility
by: Mohamad Isa, Irma Izani, et al.
Published: (2020)

Identification and characterization of copy number variations (CNVs) in dengue patients and its impact with vascular leakage / Zuraihan Zakaria
by: Zakaria, Zuraihan
Published: (2016)

Identification and characterization of copy number variations (CNVs) in dengue patients and its impact with vascular leakage / Zuraihan Zakaria
by: Zakaria, Zuraihan
Published: (2016)

Obesity, starch digestion and amylase: association between copy number variants at human salivary (AMY1) and pancreatic (AMY2) amylase genes
by: Carpenter, Danielle, et al.
Published: (2015)

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants.
by: Sulak, Michael, et al.
Published: (2016)

TP53 copy number expansion is associated with the evolution of increased body size and an enhanced DNA damage response in elephants
by: Sulak, Michael, et al.
Published: (2016)

Understanding the role of copy number (CNV) in the development of left ventricular hypertrophy in hypertension / Khalid Yusoff and Hoh Boon Peng
by: Yusoff, Khalid, et al.
Published: (2012)

Copy number variation of FCGR3B gene among severe dengue patient in Malaysia / Umi Shakina Haridan
by: Haridan, Umi Shakina
Published: (2015)

Estimation of 16S RNA gene copy number in several probiotic Lactobacillus strains isolated from the gastrointestinal tract of chicken.
by: Chin, Mei Lee, et al.
Published: (2008)

Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia
by: Ambayya @ Ampiah, A Angeli
Published: (2015)

Association of copy number variations in complement factor H-related genes among age-related macular degenerative subjects
by: Md Bakri, Norshakimah, et al.
Published: (2017)

Distribution of CCL3L1 copy number variable gene among three major ethnic groups in Malaysia
by: Jamaluddin, Jalilah
Published: (2017)

Microarray-based genomic analysis identifies germline and somatic copy number variants and loss of heterozygosity in acute myeloid leukaemia
by: Ambayya @ Ampiah, A Angeli, et al.
Published: (2018)

Determination of phosphatidylinositol-3-kinase gene copy number and protein expression in nasopharyngeal carcinoma by real-time PCR and immunohistochemistry
by: Firoozinia, Mohammad
Published: (2013)