Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens.
The ever rising resistant bacteria and fungi resulted in finding novel antimicrobial sources and agents. Studies confirmed that mung beans have increased phenolic compounds and enhanced defenses during germination. We hypothesized that antimicrobial activities might be found in sprouts of mung beans...
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| Format: | Article |
| Language: | English English |
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Academic Journals
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24121/ http://psasir.upm.edu.my/id/eprint/24121/1/Novel%20in.pdf |
| _version_ | 1848844947738853376 |
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| author | Abu Bakar, Fatimah Abas, Faridah Sekawi, Zamberi Hafidh, Rand Riadh A. S., Abdulamir Law, Se Vern |
| author_facet | Abu Bakar, Fatimah Abas, Faridah Sekawi, Zamberi Hafidh, Rand Riadh A. S., Abdulamir Law, Se Vern |
| author_sort | Abu Bakar, Fatimah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The ever rising resistant bacteria and fungi resulted in finding novel antimicrobial sources and agents. Studies confirmed that mung beans have increased phenolic compounds and enhanced defenses during germination. We hypothesized that antimicrobial activities might be found in sprouts of mung beans (MBS), or Vigna radiata (L.) R. Wilczek. The screening method was conducted using disc diffusion assay against 12 gram negative and positive bacteria, including multiple drug resistant (MDR) bacteria and 12 fungi. It was followed by the evaluation of the minimum inhibitory concentration and the minimum bactericidal concentration or the minimum fungicidal concentration. The screening results revealed potential antibacterial and antifungal activities by MBS extract against 11 out of 12 bacteria and 2 out of 10 fungi including remarkable antimicrobial activity against highly infectious MDR bugs such as Methicilline-resistant Staphylococcus aureus, MDR Escherichia coli O157:H7, MDR Pseudomonas aeruginosa, Klebsiella pneumoniae, S. aureus, and Salmonella Typhimurium as well as against human fungal pathogens, Trichophyton rubrum and Trichoderma harzianum. The potential antimicrobial activity of MBS reflects effective quality and quantity of polyphenolic compounds present after bean germination. This unprecedented study showed that MBS extract is a potential source for novel antimicrobials that are inexpensive and readily available at a large scale for pharmaceutical companies. |
| first_indexed | 2025-11-15T08:39:01Z |
| format | Article |
| id | upm-24121 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:39:01Z |
| publishDate | 2011 |
| publisher | Academic Journals |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-241212015-09-30T01:57:20Z http://psasir.upm.edu.my/id/eprint/24121/ Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. Abu Bakar, Fatimah Abas, Faridah Sekawi, Zamberi Hafidh, Rand Riadh A. S., Abdulamir Law, Se Vern The ever rising resistant bacteria and fungi resulted in finding novel antimicrobial sources and agents. Studies confirmed that mung beans have increased phenolic compounds and enhanced defenses during germination. We hypothesized that antimicrobial activities might be found in sprouts of mung beans (MBS), or Vigna radiata (L.) R. Wilczek. The screening method was conducted using disc diffusion assay against 12 gram negative and positive bacteria, including multiple drug resistant (MDR) bacteria and 12 fungi. It was followed by the evaluation of the minimum inhibitory concentration and the minimum bactericidal concentration or the minimum fungicidal concentration. The screening results revealed potential antibacterial and antifungal activities by MBS extract against 11 out of 12 bacteria and 2 out of 10 fungi including remarkable antimicrobial activity against highly infectious MDR bugs such as Methicilline-resistant Staphylococcus aureus, MDR Escherichia coli O157:H7, MDR Pseudomonas aeruginosa, Klebsiella pneumoniae, S. aureus, and Salmonella Typhimurium as well as against human fungal pathogens, Trichophyton rubrum and Trichoderma harzianum. The potential antimicrobial activity of MBS reflects effective quality and quantity of polyphenolic compounds present after bean germination. This unprecedented study showed that MBS extract is a potential source for novel antimicrobials that are inexpensive and readily available at a large scale for pharmaceutical companies. Academic Journals 2011-08 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24121/1/Novel%20in.pdf Abu Bakar, Fatimah and Abas, Faridah and Sekawi, Zamberi and Hafidh, Rand Riadh and A. S., Abdulamir and Law, Se Vern (2011) Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. Journal of Medicinal Plants Research, 5 (16). pp. 3606-3618. ISSN 1996-0875 http://www.academicjournals.org/ English |
| spellingShingle | Abu Bakar, Fatimah Abas, Faridah Sekawi, Zamberi Hafidh, Rand Riadh A. S., Abdulamir Law, Se Vern Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title | Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title_full | Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title_fullStr | Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title_full_unstemmed | Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title_short | Novel in-vitro antimicrobial activity of Vigna radiata (L.)R. Wilczek against highly resistant bacterial and fungal pthogens. |
| title_sort | novel in-vitro antimicrobial activity of vigna radiata (l.)r. wilczek against highly resistant bacterial and fungal pthogens. |
| url | http://psasir.upm.edu.my/id/eprint/24121/ http://psasir.upm.edu.my/id/eprint/24121/ http://psasir.upm.edu.my/id/eprint/24121/1/Novel%20in.pdf |