Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study
Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune...
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| Format: | Article |
| Language: | English |
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Science Publications
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24112/ http://psasir.upm.edu.my/id/eprint/24112/1/Evaluation%20of%20immunomodulatory%20effect.pdf |
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| author | Yeap, Swee Keong Abd Rahman, Mashitoh Mohammed Alitheen, Noorjahan Banu Ho, Wan Yong Omar, Abdul Rahman Beh, Boon Kee Ky, Huynh |
| author_facet | Yeap, Swee Keong Abd Rahman, Mashitoh Mohammed Alitheen, Noorjahan Banu Ho, Wan Yong Omar, Abdul Rahman Beh, Boon Kee Ky, Huynh |
| author_sort | Yeap, Swee Keong |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting proper immune cells from a suitable immune organ allowed for the understanding on the mode of immunomodulation. Lymphocytes isolated from mammalian thymus, spleen and bone marrow represented great candidates for this immunomodulatory study. Results: A number of herbal extracts including that of Rhaphidophora korthalsii and compounds isolated from this plant, namely lectin and zerumbone, had been identified as potent immunostimulators. Conclusion/Recommendations: Future studies are needed to elucidate the mechanism underlaying activites of these immunomodulatory agents. |
| first_indexed | 2025-11-15T08:38:59Z |
| format | Article |
| id | upm-24112 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:38:59Z |
| publishDate | 2011 |
| publisher | Science Publications |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-241122017-09-28T09:57:26Z http://psasir.upm.edu.my/id/eprint/24112/ Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study Yeap, Swee Keong Abd Rahman, Mashitoh Mohammed Alitheen, Noorjahan Banu Ho, Wan Yong Omar, Abdul Rahman Beh, Boon Kee Ky, Huynh Problem statement: Numerous plants or remedies that are traditionally used for various diseases had been claimed to maintain general good health, particularly the immune system. With the advanced understanding on immunology and ethnopharmacology, study on the interaction of this herb with the immune system is critical to understand the safety and its efficacy as a potent immunomodulatory agent. Approach: Selecting proper immune cells from a suitable immune organ allowed for the understanding on the mode of immunomodulation. Lymphocytes isolated from mammalian thymus, spleen and bone marrow represented great candidates for this immunomodulatory study. Results: A number of herbal extracts including that of Rhaphidophora korthalsii and compounds isolated from this plant, namely lectin and zerumbone, had been identified as potent immunostimulators. Conclusion/Recommendations: Future studies are needed to elucidate the mechanism underlaying activites of these immunomodulatory agents. Science Publications 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24112/1/Evaluation%20of%20immunomodulatory%20effect.pdf Yeap, Swee Keong and Abd Rahman, Mashitoh and Mohammed Alitheen, Noorjahan Banu and Ho, Wan Yong and Omar, Abdul Rahman and Beh, Boon Kee and Ky, Huynh (2011) Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study. American Journal of Immunology, 7 (2). pp. 17-23. ISSN 1553-619X; ESSN: 1558-3775 http://thescipub.com/html/10.3844/ajisp.2011.17.23 10.3844/ajisp.2011.17.23 |
| spellingShingle | Yeap, Swee Keong Abd Rahman, Mashitoh Mohammed Alitheen, Noorjahan Banu Ho, Wan Yong Omar, Abdul Rahman Beh, Boon Kee Ky, Huynh Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title | Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title_full | Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title_fullStr | Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title_full_unstemmed | Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title_short | Evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| title_sort | evaluation of immunomodulatory effect: selection of the correct targets for immunostimulation study |
| url | http://psasir.upm.edu.my/id/eprint/24112/ http://psasir.upm.edu.my/id/eprint/24112/ http://psasir.upm.edu.my/id/eprint/24112/ http://psasir.upm.edu.my/id/eprint/24112/1/Evaluation%20of%20immunomodulatory%20effect.pdf |