A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages..

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A curcumin derivative, 2,6-bis(2,5-dimethoxybenzylidene)-cyclohexanone (BDMC33) attenuates prostaglandin E2 synthesis via selective suppression of cyclooxygenase-2 in IFN-γ/LPS-stimulated macrophages..

Our preliminary screening had shown that the curcumin derivative [2,6-bis(2,5- dimethoxybenzylidene)cyclohexanone] or BDMC33 exhibited improved anti-inflammatory activity by inhibiting nitric oxide synthesis in activated macrophage cells. In this study, we further investigated the anti-inflammatory...

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Bibliographic Details
Main Authors:	Lee, Ka Heng, Abas, Faridah, Mohamed Alitheen, Noorjahan Banu, Shaari, Khozirah, Lajis, Md. Nordin, Ahmad, Syahida
Format:	Article
Language:	English English
Published:	MDPI 2011
Online Access:	http://psasir.upm.edu.my/id/eprint/24101/ http://psasir.upm.edu.my/id/eprint/24101/1/A%20curcumin%20derivative.pdf

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