Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).

Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant...

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Main Authors: Chong, Hueh Zan, Rahmat, Asmah, Md. Akim, Abdah, Mohamed Alitheen, Noorjahan Banu, Othman, Fauziah, Cheng, Gwendoline Lian Ee
Format: Article
Language:English
English
Published: Emerald Group Publishing 2011
Online Access:http://psasir.upm.edu.my/id/eprint/24087/
http://psasir.upm.edu.my/id/eprint/24087/1/Anti.pdf
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author Chong, Hueh Zan
Rahmat, Asmah
Md. Akim, Abdah
Mohamed Alitheen, Noorjahan Banu
Othman, Fauziah
Cheng, Gwendoline Lian Ee
author_facet Chong, Hueh Zan
Rahmat, Asmah
Md. Akim, Abdah
Mohamed Alitheen, Noorjahan Banu
Othman, Fauziah
Cheng, Gwendoline Lian Ee
author_sort Chong, Hueh Zan
building UPM Institutional Repository
collection Online Access
description Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts(0-100mg/ml) using 72-h MTT assay. Findings – Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma),HT-29 (colon carcinoma), MDA-MB-231 (non-hormone-dependent breast cancer), MCF-7(hormone-dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC50) were obtained for MDA-MB-231, HepG2, HT-29. Extracts within the concentrations of 10-100mg/ml were found not to be effective against proliferation of MCF-7 and HeLa.
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institution Universiti Putra Malaysia
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language English
English
last_indexed 2025-11-15T08:38:52Z
publishDate 2011
publisher Emerald Group Publishing
recordtype eprints
repository_type Digital Repository
spelling upm-240872015-10-05T09:19:59Z http://psasir.upm.edu.my/id/eprint/24087/ Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa). Chong, Hueh Zan Rahmat, Asmah Md. Akim, Abdah Mohamed Alitheen, Noorjahan Banu Othman, Fauziah Cheng, Gwendoline Lian Ee Purpose – The purpose of this paper is to screen cytotoxic activities of commonly used culinary plants in Malaysia, Pandanus amaryllifolius (daun pandan), Curcuma longa (turmeric leaves) and Etlingera elatior (kantan flower) against selected cancer cell lines. Design/methodology/approach – Plant samples were extracted exhaustively with ethanol and concentrated under rotary evaporator. Cytotoxic evaluation was carried out with plant extracts(0-100mg/ml) using 72-h MTT assay. Findings – Exposure of plant extracts reduced cell viability of HepG2 (hepatocellular carcinoma),HT-29 (colon carcinoma), MDA-MB-231 (non-hormone-dependent breast cancer), MCF-7(hormone-dependent breast cancer) and HeLa (cervical cancer); 50 percent inhibitory values (IC50) were obtained for MDA-MB-231, HepG2, HT-29. Extracts within the concentrations of 10-100mg/ml were found not to be effective against proliferation of MCF-7 and HeLa. Emerald Group Publishing 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24087/1/Anti.pdf Chong, Hueh Zan and Rahmat, Asmah and Md. Akim, Abdah and Mohamed Alitheen, Noorjahan Banu and Othman, Fauziah and Cheng, Gwendoline Lian Ee (2011) Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa). Nutrition and Food Science, 41 (4). pp. 238-241. ISSN 0034-6659 10.1108/00346651111151366 English
spellingShingle Chong, Hueh Zan
Rahmat, Asmah
Md. Akim, Abdah
Mohamed Alitheen, Noorjahan Banu
Othman, Fauziah
Cheng, Gwendoline Lian Ee
Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title_full Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title_fullStr Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title_full_unstemmed Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title_short Anti-proliferative effects of pandan leaves (Pandanus amarylfolius), kantan flower(Etlingera elatior) and turmeric leaves (Curcuma longa).
title_sort anti-proliferative effects of pandan leaves (pandanus amarylfolius), kantan flower(etlingera elatior) and turmeric leaves (curcuma longa).
url http://psasir.upm.edu.my/id/eprint/24087/
http://psasir.upm.edu.my/id/eprint/24087/
http://psasir.upm.edu.my/id/eprint/24087/1/Anti.pdf