The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role.
Streptococcus bovis (S. bovis) bacteria are associated with colorectal cancer and adenoma. S. bovis is currently named S. gallolyticus. 25 to 80% of patients with S. bovis/gallolyticus bacteremia have concomitant colorectal tumors. Colonic neoplasia may arise years after the presentation of bacterem...
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| Format: | Article |
| Language: | English English |
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BioMed Central
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24052/ http://psasir.upm.edu.my/id/eprint/24052/1/The%20association%20of%20Streptococcus%20bovis.pdf |
| _version_ | 1848844929034354688 |
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| author | Abdulamir, Ahmed Sahib Hafidh, Rand Riadh Abu Bakar, Fatimah |
| author_facet | Abdulamir, Ahmed Sahib Hafidh, Rand Riadh Abu Bakar, Fatimah |
| author_sort | Abdulamir, Ahmed Sahib |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Streptococcus bovis (S. bovis) bacteria are associated with colorectal cancer and adenoma. S. bovis is currently named S. gallolyticus. 25 to 80% of patients with S. bovis/gallolyticus bacteremia have concomitant colorectal tumors. Colonic neoplasia may arise years after the presentation of bacteremia or infectious endocarditis of S. bovis/gallolyticus. The presence of S. bovis/gallolyticus bacteremia and/or endocarditis is also related to the presence of villous or tubular-villous adenomas in the large intestine. In addition, serological relationship of S. gallolyticus with colorectal tumors and direct colonization of S. gallolyticus in tissues of colorectal tumors were found. However, this association is still under controversy and has long been underestimated. Moreover, the etiological versus non-etiological nature of this associationis not settled yet. Therefore, by covering the most of up to date studies, this review attempts to clarify the nature and the core of S. bovis/gallolyicus association with colorectal tumors and analyze the possible underlying mechanisms. |
| first_indexed | 2025-11-15T08:38:43Z |
| format | Article |
| id | upm-24052 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:38:43Z |
| publishDate | 2011 |
| publisher | BioMed Central |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-240522015-10-21T06:51:46Z http://psasir.upm.edu.my/id/eprint/24052/ The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. Abdulamir, Ahmed Sahib Hafidh, Rand Riadh Abu Bakar, Fatimah Streptococcus bovis (S. bovis) bacteria are associated with colorectal cancer and adenoma. S. bovis is currently named S. gallolyticus. 25 to 80% of patients with S. bovis/gallolyticus bacteremia have concomitant colorectal tumors. Colonic neoplasia may arise years after the presentation of bacteremia or infectious endocarditis of S. bovis/gallolyticus. The presence of S. bovis/gallolyticus bacteremia and/or endocarditis is also related to the presence of villous or tubular-villous adenomas in the large intestine. In addition, serological relationship of S. gallolyticus with colorectal tumors and direct colonization of S. gallolyticus in tissues of colorectal tumors were found. However, this association is still under controversy and has long been underestimated. Moreover, the etiological versus non-etiological nature of this associationis not settled yet. Therefore, by covering the most of up to date studies, this review attempts to clarify the nature and the core of S. bovis/gallolyicus association with colorectal tumors and analyze the possible underlying mechanisms. BioMed Central 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24052/1/The%20association%20of%20Streptococcus%20bovis.pdf Abdulamir, Ahmed Sahib and Hafidh, Rand Riadh and Abu Bakar, Fatimah (2011) The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. Journal of Experimental and Clinical Cancer Research, 30 (11). pp. 1-13. ISSN 1756-9966 10.1186/1756-9966-30-11 English |
| spellingShingle | Abdulamir, Ahmed Sahib Hafidh, Rand Riadh Abu Bakar, Fatimah The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title | The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title_full | The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title_fullStr | The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title_full_unstemmed | The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title_short | The association of Streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| title_sort | association of streptococcus bovis/gallolyticus with colorectal tumors : the nature and the underlying mechanisms of its etiological role. |
| url | http://psasir.upm.edu.my/id/eprint/24052/ http://psasir.upm.edu.my/id/eprint/24052/ http://psasir.upm.edu.my/id/eprint/24052/1/The%20association%20of%20Streptococcus%20bovis.pdf |