Anti-pancreatic lipase and antioxidant activity of selected tropical herbs.
The anti-pancreatic lipase and antioxidant activity of Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract were evaluated for potential use as an anti-obesity agent. Antioxidant activity of the extracts was determined using 2,2-diphenyl-1-picrylhdrazyl and ferric-reducing an...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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Taylor & Francis
2012
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| Online Access: | http://psasir.upm.edu.my/id/eprint/24030/ http://psasir.upm.edu.my/id/eprint/24030/1/Anti-pancreatic%20lipase%20and%20antioxidant%20activity%20of%20selected%20tropical%20herbs..pdf |
| _version_ | 1848844922888650752 |
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| author | Sahib, Najla Gooda Abdul Hamid, Azizah Saari, Nazamid Abas, Faridah Pak Dek, Mohd Sabri Rahim, Mustupha |
| author_facet | Sahib, Najla Gooda Abdul Hamid, Azizah Saari, Nazamid Abas, Faridah Pak Dek, Mohd Sabri Rahim, Mustupha |
| author_sort | Sahib, Najla Gooda |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The anti-pancreatic lipase and antioxidant activity of Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract were evaluated for potential use as an anti-obesity agent. Antioxidant activity of the extracts was determined using 2,2-diphenyl-1-picrylhdrazyl and ferric-reducing antioxidant power assays. Inhibition of pancreatic lipase was measured in vitro. Results from this study showed that Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract exhibited different levels of antioxidant activity, with IC50 ranging from 0.90 ± 0.1 to 3.7 ± 0.8 mg/mL of extracts. All extracts were found to inhibit pancreatic lipase activity, with Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract demonstrating 21.0 ± 1.3, 25.8 ± 0.1, and 25.3 ± 0.4% inhibition, respectively. |
| first_indexed | 2025-11-15T08:38:37Z |
| format | Article |
| id | upm-24030 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:38:37Z |
| publishDate | 2012 |
| publisher | Taylor & Francis |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-240302016-02-17T02:45:23Z http://psasir.upm.edu.my/id/eprint/24030/ Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. Sahib, Najla Gooda Abdul Hamid, Azizah Saari, Nazamid Abas, Faridah Pak Dek, Mohd Sabri Rahim, Mustupha The anti-pancreatic lipase and antioxidant activity of Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract were evaluated for potential use as an anti-obesity agent. Antioxidant activity of the extracts was determined using 2,2-diphenyl-1-picrylhdrazyl and ferric-reducing antioxidant power assays. Inhibition of pancreatic lipase was measured in vitro. Results from this study showed that Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract exhibited different levels of antioxidant activity, with IC50 ranging from 0.90 ± 0.1 to 3.7 ± 0.8 mg/mL of extracts. All extracts were found to inhibit pancreatic lipase activity, with Momordica charantia, Morinda citrifolia fruit, and Centella asiatica extract demonstrating 21.0 ± 1.3, 25.8 ± 0.1, and 25.3 ± 0.4% inhibition, respectively. Taylor & Francis 2012 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/24030/1/Anti-pancreatic%20lipase%20and%20antioxidant%20activity%20of%20selected%20tropical%20herbs..pdf Sahib, Najla Gooda and Abdul Hamid, Azizah and Saari, Nazamid and Abas, Faridah and Pak Dek, Mohd Sabri and Rahim, Mustupha (2012) Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. International Journal of Food Properties, 15 (3). pp. 569-578. ISSN 1094-2912; ESSN: 1532-2386 10.1080/10942912.2010.494754 English |
| spellingShingle | Sahib, Najla Gooda Abdul Hamid, Azizah Saari, Nazamid Abas, Faridah Pak Dek, Mohd Sabri Rahim, Mustupha Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title | Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title_full | Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title_fullStr | Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title_full_unstemmed | Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title_short | Anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| title_sort | anti-pancreatic lipase and antioxidant activity of selected tropical herbs. |
| url | http://psasir.upm.edu.my/id/eprint/24030/ http://psasir.upm.edu.my/id/eprint/24030/ http://psasir.upm.edu.my/id/eprint/24030/1/Anti-pancreatic%20lipase%20and%20antioxidant%20activity%20of%20selected%20tropical%20herbs..pdf |