Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzymes inhibition

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Anti-inflammatory activities of cucurbitacin E isolated from Citrullus lanatus var. citroides: role of reactive nitrogen species and cyclooxygenase enzymes inhibition

The in vivo and in vitro mechanistic anti-inflammatory actions of cucurbitacin E (CE) (Citrullus lanatus var. citroides) were examined. The results showed that LPS/INF-γ increased NO production in RAW264.7 macrophages, whereas L-NAME and CE curtailed it. CE did not reveal any cytotoxicity on RAW264....

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Bibliographic Details
Main Authors:	Abdelwahab, Siddig Ibrahim, Ahmed Hassan, Loiy Elsir, Mohd Sirat, Hasnah, Mohamed Ahmed Yagi, Sakina, Mohamed, Waleed Sayed Koko, Mohan, Syam, Taha, Manal Mohamed Elhassan, Ahmad, Syahida, Cheah, Shiau Chuen, Mohd Fauzi, Putri Narrima, Rais, Mohd Mustafa, A. Hadi, A. Hamid
Format:	Article
Published:	Elsevier 2011
Online Access:	http://psasir.upm.edu.my/id/eprint/22371/

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