Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit
Phaleria macrocarpa (Scheff.) Boerl (Thymelaceae) is commonly known as ‘Crown of God’, ‘Mahkota Dewa’, and ‘Pau’. It originates from Papua Island, Indonesia and it grows in tropical areas. Empirically, it is potent in treating the hypertensive,diabetic, cancer and diuretic patients. It has a long hi...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2011
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/22332/ http://psasir.upm.edu.my/id/eprint/22332/1/Flavonoid%20Analyses%20and%20Antimicrobial%20Activity%20of%20Various%20Parts%20of%20Phaleria%20macrocarpa.pdf |
| _version_ | 1848844457081831424 |
|---|---|
| author | Hendra, Rudi Ahmad, Syahida Md. Sukari, Mohd. Aspollah Abd. Shukor, Mohd. Yunus Oskoueian, Ehsan |
| author_facet | Hendra, Rudi Ahmad, Syahida Md. Sukari, Mohd. Aspollah Abd. Shukor, Mohd. Yunus Oskoueian, Ehsan |
| author_sort | Hendra, Rudi |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Phaleria macrocarpa (Scheff.) Boerl (Thymelaceae) is commonly known as ‘Crown of God’, ‘Mahkota Dewa’, and ‘Pau’. It originates from Papua Island, Indonesia and it grows in tropical areas. Empirically, it is potent in treating the hypertensive,diabetic, cancer and diuretic patients. It has a long history of ethnopharmacological usage, and the lack of information about its biological activities led us to investigate the possible biological activities by characterisation of flavonoids and antimicrobial activity of various part of P. macrocarpa against pathogenic bacteria and fungi. The results showed that kaempferol, myricetin, naringin, and rutin were the major flavonoids present in the pericarp while naringin and quercetin were found in the mesocarp and seed. Furthermore, the antibacterial activity of different parts of P. macrocarpa fruit showed a weak ability to moderate antibacterial activity against pathogenic tested bacteria (inhibition range: 0.93–2.17 cm) at concentration of 0.3 mg/disc. The anti fungi activity was only found in seed extract against Aspergillus niger (1.87 cm) at concentration of 0.3 mg/well. From the results obtained, P. macrocarpa fruit could be considered as a natural antimicrobial source due to the presence of flavonoid compounds. |
| first_indexed | 2025-11-15T08:31:13Z |
| format | Article |
| id | upm-22332 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:31:13Z |
| publishDate | 2011 |
| publisher | MDPI AG |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-223322015-09-25T07:57:16Z http://psasir.upm.edu.my/id/eprint/22332/ Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit Hendra, Rudi Ahmad, Syahida Md. Sukari, Mohd. Aspollah Abd. Shukor, Mohd. Yunus Oskoueian, Ehsan Phaleria macrocarpa (Scheff.) Boerl (Thymelaceae) is commonly known as ‘Crown of God’, ‘Mahkota Dewa’, and ‘Pau’. It originates from Papua Island, Indonesia and it grows in tropical areas. Empirically, it is potent in treating the hypertensive,diabetic, cancer and diuretic patients. It has a long history of ethnopharmacological usage, and the lack of information about its biological activities led us to investigate the possible biological activities by characterisation of flavonoids and antimicrobial activity of various part of P. macrocarpa against pathogenic bacteria and fungi. The results showed that kaempferol, myricetin, naringin, and rutin were the major flavonoids present in the pericarp while naringin and quercetin were found in the mesocarp and seed. Furthermore, the antibacterial activity of different parts of P. macrocarpa fruit showed a weak ability to moderate antibacterial activity against pathogenic tested bacteria (inhibition range: 0.93–2.17 cm) at concentration of 0.3 mg/disc. The anti fungi activity was only found in seed extract against Aspergillus niger (1.87 cm) at concentration of 0.3 mg/well. From the results obtained, P. macrocarpa fruit could be considered as a natural antimicrobial source due to the presence of flavonoid compounds. MDPI AG 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/22332/1/Flavonoid%20Analyses%20and%20Antimicrobial%20Activity%20of%20Various%20Parts%20of%20Phaleria%20macrocarpa.pdf Hendra, Rudi and Ahmad, Syahida and Md. Sukari, Mohd. Aspollah and Abd. Shukor, Mohd. Yunus and Oskoueian, Ehsan (2011) Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit. International Journal of Molecular Sciences, 12 (16). pp. 3422-3431. ISSN 1422-0067 http://www.mdpi.com/1422-0067/12/6/3422 10.3390/ijms12063422 |
| spellingShingle | Hendra, Rudi Ahmad, Syahida Md. Sukari, Mohd. Aspollah Abd. Shukor, Mohd. Yunus Oskoueian, Ehsan Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title | Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title_full | Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title_fullStr | Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title_full_unstemmed | Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title_short | Flavonoid analyses and antimicrobial activity of various parts of Phaleria macrocarpa (Scheff.) Boerl fruit |
| title_sort | flavonoid analyses and antimicrobial activity of various parts of phaleria macrocarpa (scheff.) boerl fruit |
| url | http://psasir.upm.edu.my/id/eprint/22332/ http://psasir.upm.edu.my/id/eprint/22332/ http://psasir.upm.edu.my/id/eprint/22332/ http://psasir.upm.edu.my/id/eprint/22332/1/Flavonoid%20Analyses%20and%20Antimicrobial%20Activity%20of%20Various%20Parts%20of%20Phaleria%20macrocarpa.pdf |