Preparation and characterisation of water-soluble phytosterol nanodispersions.

The purpose of this study was to prepare and characterise water-soluble phytosterol nanodispersions for food formulation. The effects of several factors were examined: four different types of organic phases (hexane, isopropyl alcohol, ethanol and acetone), the organic to aqueous phase ratio and conv...

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Main Authors: Leong, Wai Fun, Lai, Oi Ming, Long, Kamariah, Che Man, Yaakob, Misran, Misni, Tan, Chin Ping
Format: Article
Language:English
English
Published: Elsevier 2011
Online Access:http://psasir.upm.edu.my/id/eprint/22295/
http://psasir.upm.edu.my/id/eprint/22295/1/Preparation%20and%20characterisation%20of%20water.pdf
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author Leong, Wai Fun
Lai, Oi Ming
Long, Kamariah
Che Man, Yaakob
Misran, Misni
Tan, Chin Ping
author_facet Leong, Wai Fun
Lai, Oi Ming
Long, Kamariah
Che Man, Yaakob
Misran, Misni
Tan, Chin Ping
author_sort Leong, Wai Fun
building UPM Institutional Repository
collection Online Access
description The purpose of this study was to prepare and characterise water-soluble phytosterol nanodispersions for food formulation. The effects of several factors were examined: four different types of organic phases (hexane, isopropyl alcohol, ethanol and acetone), the organic to aqueous phase ratio and conventional homogenisation vs. high-pressure homogenisation. We demonstrated the feasibility of phytosterol nanodispersions production using an emulsification–evaporation technique. The results showed that hexane was able to produce the smallest particle size at a mean diameter of approximately 50 nm at monomodal distribution. Phytosterol nanodispersions prepared with a higher homogenisation pressure and a higher organic to aqueous phase ratio resulted in significantly larger phytosterol nanoparticles (P < 0.05). Phytosterol loss after high-pressure homogenisation ranged from 3% to 28%, and losses increased with increasing homogenisation pressure. Elimination of the organic phase by evaporation resulted in a phytosterol loss of 0.5–9%.
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spelling upm-222952015-10-02T03:43:57Z http://psasir.upm.edu.my/id/eprint/22295/ Preparation and characterisation of water-soluble phytosterol nanodispersions. Leong, Wai Fun Lai, Oi Ming Long, Kamariah Che Man, Yaakob Misran, Misni Tan, Chin Ping The purpose of this study was to prepare and characterise water-soluble phytosterol nanodispersions for food formulation. The effects of several factors were examined: four different types of organic phases (hexane, isopropyl alcohol, ethanol and acetone), the organic to aqueous phase ratio and conventional homogenisation vs. high-pressure homogenisation. We demonstrated the feasibility of phytosterol nanodispersions production using an emulsification–evaporation technique. The results showed that hexane was able to produce the smallest particle size at a mean diameter of approximately 50 nm at monomodal distribution. Phytosterol nanodispersions prepared with a higher homogenisation pressure and a higher organic to aqueous phase ratio resulted in significantly larger phytosterol nanoparticles (P < 0.05). Phytosterol loss after high-pressure homogenisation ranged from 3% to 28%, and losses increased with increasing homogenisation pressure. Elimination of the organic phase by evaporation resulted in a phytosterol loss of 0.5–9%. Elsevier 2011-11-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/22295/1/Preparation%20and%20characterisation%20of%20water.pdf Leong, Wai Fun and Lai, Oi Ming and Long, Kamariah and Che Man, Yaakob and Misran, Misni and Tan, Chin Ping (2011) Preparation and characterisation of water-soluble phytosterol nanodispersions. Food Chemistry, 129 (1). pp. 77-83. ISSN 0308-8146 10.1016/j.foodchem.2011.04.027 English
spellingShingle Leong, Wai Fun
Lai, Oi Ming
Long, Kamariah
Che Man, Yaakob
Misran, Misni
Tan, Chin Ping
Preparation and characterisation of water-soluble phytosterol nanodispersions.
title Preparation and characterisation of water-soluble phytosterol nanodispersions.
title_full Preparation and characterisation of water-soluble phytosterol nanodispersions.
title_fullStr Preparation and characterisation of water-soluble phytosterol nanodispersions.
title_full_unstemmed Preparation and characterisation of water-soluble phytosterol nanodispersions.
title_short Preparation and characterisation of water-soluble phytosterol nanodispersions.
title_sort preparation and characterisation of water-soluble phytosterol nanodispersions.
url http://psasir.upm.edu.my/id/eprint/22295/
http://psasir.upm.edu.my/id/eprint/22295/
http://psasir.upm.edu.my/id/eprint/22295/1/Preparation%20and%20characterisation%20of%20water.pdf