Effects of CXCR4 Silencing by Sirna Engrafted Cotionized Dextran in Mouse Models of Colorectal Cancer and Liver Metastasis

QR Code

Effects of CXCR4 Silencing by Sirna Engrafted Cotionized Dextran in Mouse Models of Colorectal Cancer and Liver Metastasis

Liver metastasis is the main cause of colorectal cancer related mortality. CXCR4 is necessary for the outgrowth of colon cancer micrometastasis. CXCR4 gene expression and serum total lactate dehydrogenase, creatine kinase and alkaline phosphatase levels are often increased in patients with colorecta...

Full description

Bibliographic Details
Main Author:	Abedini, Fatemeh
Format:	Thesis
Language:	English English
Published:	2011
Subjects:	Colon (Anatomy) - Cancer Rectum - Cancer Liver - Cancer
Online Access:	http://psasir.upm.edu.my/id/eprint/19675/ http://psasir.upm.edu.my/id/eprint/19675/1/IB_2011_6.pdf

Similar Items

Investigation into the controversial association of Streptococcus gallolyticus with colorectal cancer and adenoma.
by: Abdulamir, Ahmed Sahib, et al.
Published: (2009)

Relationships between Wnt-Notch-Hippo signaling pathways and their relevance to colorectal cancer pathogenesis
by: Chai, Boon Lee
Published: (2018)

Molecular detection, quantification, and isolation of Streptococcus gallolyticus bacteria colonizing colorectal tumors: inflammation-driven potential of carcinogenesis via IL-1, COX-2, and IL-8.
by: Abdulamir, Ahmed Sahib, et al.
Published: (2010)

Effect of gamma-oryzanol, oryzanol rich fraction and fractioned components on colorectal cancer cell line (HT-29) and cytokine production by human peripheral blood mononuclear cells
by: Alishavandi, Sima
Published: (2011)

Properties of vanillin and its effects on colorectal cancer in vitro and in vivo
by: Ho, Ket Li
Published: (2011)

A Combined Recombinant Retroviral-Based Therapy for Colon Cancer in the Murine Model Using Anti-Tumorigenic and Anti-Angiogenic Agents
by: Nik Abd. Rahman, Nik Mohd. Afizan
Published: (2011)

Effects of CXCR4 siRNA/dextran-spermine nanoparticles on CXCR4 expression and serum LDH levels in a mouse model of colorectal cancer metastasis to the liver.
by: Abedini, Fatemeh, et al.
Published: (2011)

Characterisation of Lactococcus lactis M4 carrying dual-expression plasmid to demonstrate bactofection of human colon cancer cell line, SW620
by: Faroque, Habibah
Published: (2017)

Combination therapy using plasmid DNA-mediated VP3 and SHCD147 genes for colon cancer in a murine model
by: Ismail, Ruzila
Published: (2014)

Characterization and chemoresistance of HT29 (Colon cancer) and TW06 (Nasopharyngeal cancer) tumorspheres
by: Goh, Iris Wen Li
Published: (2014)

The inter-relationship between p53, survivin and XIAP in colorectal cancer cells response to apoptotic stimuli
by: Atakpa, Isaac
Published: (2024)

Induction of apoptosis via JNK and AKT/mTOR signaling pathways by Alternanthera sessilis (L.) R.Br. ex DC. in colorectal cancer in vitro and in vivo
by: Sivapragasam, Gothai
Published: (2019)

Effects of silencing dishevelled 1, 2 and 3 mRNA expression on MDA-MB-231 cell migration and invasion using siRNAs
by: Khoo, Samuel Leon Juan
Published: (2015)

Recombinant Adenovirus Expressing Anti-Cancer Gene in Colon Cancer Cell Explant in Mice
by: Tan, Seok Shin
Published: (2010)

Effects of supercritical fluid-extracted Hibiscus cannabinus L. seed oil on colon cancer in vitro and in vivo
by: Abd Ghafar, Siti Aisyah
Published: (2013)

Analysis of V-Ki-Ras2 Kirsten rat sarcoma viral oncogene (Kras) and differential expressed miRNA in various stages of colorectal cancer
by: Lye, Kwan Liang
Published: (2013)

Evaluation of Newcastle disease virus as an oncolytic agent in colorectal cancer cell lines
by: Chia, Suet Lin
Published: (2012)

Investigation of Cten signalling and regulation in colorectal cancer
by: Akhlaq, Maham
Published: (2016)

A novel approach toward colon cancer treatment involving mucoadhesion and tumour-targeting of curcumin-containing nanoparticles
by: Sabra, Rayan
Published: (2019)

Anti-cancer activity and mechanism of action of rice bran phytic acid on colon cancer in vitro and in vivo
by: Shafie, Nurul Husna
Published: (2013)

In-vitro investigations into endocytosis and silencing of siRNA-liposomes
by: ALSHEHRI, ABDULLAH ALI D
Published: (2017)

Epha2 sirna silencing on malignant glioma cells
by: Azman , Amy Shafinas
Published: (2017)

Potential chemoprevention of primary liver cancer using optimized formulation of Strobilanthus crispus (L.) blume and Centella asiatica L. juices
by: Hussin, Faridah
Published: (2011)

Cytotoxic Effect of Girinimbine on HepG2 Cells
by: Mohan, Suvita Syam
Published: (2011)

A trial of a self assessment tool of problems following treatment of colorectal cancer: A prospective study in Australian primary care.
by: Ngune, I, et al.
Published: (2015)

Antiproliferative effects of zerumbone-hydroxypropyl-ß-cyclodextrin inclusion complex on HepG2 liver cancer cells in vitro
by: Muhammad Nadzri, Nabilah
Published: (2013)

Characterization and cytotoxicity of clausenidin from Clausena excavata Burm f. and its effects on cell cycle regulation and apoptosis of liver (hepg2) and colon (ht29) cancer cell lines
by: Waziri, Peter Maitalata
Published: (2017)

Antitumor effects of zerumbone on rat hepatocarcinoma and HEPG2 cells
by: Taha, Manal Mohamed Elhassan
Published: (2011)

Chemopreventive potential of water and methanolic extracts of Clinacanthus nutans (Burm.f.) Lindau on colon cancer in vitro and in vivo
by: Kura, Mariamu Nyako
Published: (2015)

Cytological and molecular analysis of anti-tumour bioactivities of Urgines maritima (L.) baker aqueous extract on human malignant neuroblastoma with its neuroprotection ability / Maati Musbah Saleh Elghuol
by: Saleh Elghuol, Maati Musbah
Published: (2017)

Kesan Suplementasi Ekstrak Air Bawang Putih Mentah (Allium Sativum Linn.) Ke Atas Sel Kanser Hepar
by: Mohd Salleh, Rabeta
Published: (2002)

Liver segmentation on CT images using random walkers and fuzzy c-means for treatment planning and monitoring of tumors in liver cancer patients
by: Moghbel, Mehrdad
Published: (2017)

The Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Cancer Metastasis
by: Wong, C., et al.
Published: (2012)

Long-term survival following laparoscopic and open colectomy for colon cancer: a meta-analysis of randomized controlled trials
by: Theophilus, Mary, et al.
Published: (2014)

Study on Liposomes Integrity and Delivery of siRNA to Lung Cancer
by: Aljasser, Abdullah
Published: (2024)

Antitumor Effect of Zerumbone Isolated from Lempoyang (Zingiber Zerumbet) on Human Cervical Cancer Cells and Mouse Cervical Intraepithelial Neoplasia
by: Abdelwahab, Siddig Ibrahim
Published: (2009)

Investigating the role of Cten in metastatic colorectal cancer
by: Thorpe, Hannah
Published: (2016)

eIF4A2 is a regulator of hypoxic translation and colorectal tumour cell survival
by: Bolland, Hannah
Published: (2020)

Role of CD133 in colorectal cancer
by: Ahmed, Tarek Mohamed Abdel Moneim Mohamed Elsaba
Published: (2011)

Human rather than mouse mesenchymal stem cells in 3D co-culture models boost proliferative and migratory characteristics of colorectal cancer cells through paracrine signalling pathways, highlighting species disconnects
by: Lu, M.
Published: (2022)