Hepatotoxicity induced by antifungal drugs itraconazole and fluconazole in rats: a comparative in vivo study

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Hepatotoxicity induced by antifungal drugs itraconazole and fluconazole in rats: a comparative in vivo study

Itraconazole and fluconazole are oral antifungal drugs, which have a wide spectrum antifungal activity and better efficacy than the older drugs. However, both drugs have been associated with hepatotoxicity in susceptible patients. The mechanism of antifungal drug-induced hepatotoxicity is largely un...

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Bibliographic Details
Main Authors:	Abdullah, Muhammad Nazrul Hakim, Abdul Rahman, Nor Shahida, Ab. Hamid, Hasiah, Ahmad, Zuraini, Sulaiman, Mohd Roslan, Mohamed Mustapha, Noordin
Format:	Article
Language:	English
Published:	SAGE Publications 2004
Online Access:	http://psasir.upm.edu.my/id/eprint/18555/ http://psasir.upm.edu.my/id/eprint/18555/1/Hepatotoxicity%20induced%20by%20antifungal%20drugs%20itraconazole%20and%20fluconazole%20in%20rats.pdf

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