Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae)
Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2)...
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| Format: | Article |
| Language: | English English |
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Faculty of Science, University of Malaya
2006
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| Online Access: | http://psasir.upm.edu.my/id/eprint/18299/ http://psasir.upm.edu.my/id/eprint/18299/1/Chemical%20constituents%20and%20biological%20activities%20of%20Glycosmis%20chlorosperma%20var.pdf |
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| author | Abdullah, Rosmiati Rahmani, Mawardi Ali, Abdul Manaf Ismail, H.B.M. Sukari, Mohd Aspollah Lian, Gwendoline Ee Cheng |
| author_facet | Abdullah, Rosmiati Rahmani, Mawardi Ali, Abdul Manaf Ismail, H.B.M. Sukari, Mohd Aspollah Lian, Gwendoline Ee Cheng |
| author_sort | Abdullah, Rosmiati |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2) and (3) showed cytotoxic activity towards CEM-SS T-lymphoblastic cell lines. However, only dambullin (2) showed activity against pathogenic bacteria and fungi. We wish to report the isolation and bioassay results of the crude extracts and pure compounds. |
| first_indexed | 2025-11-15T08:15:35Z |
| format | Article |
| id | upm-18299 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:15:35Z |
| publishDate | 2006 |
| publisher | Faculty of Science, University of Malaya |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-182992015-12-09T02:34:30Z http://psasir.upm.edu.my/id/eprint/18299/ Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) Abdullah, Rosmiati Rahmani, Mawardi Ali, Abdul Manaf Ismail, H.B.M. Sukari, Mohd Aspollah Lian, Gwendoline Ee Cheng Detailed investigation on the leaves and barks of Glycosmis chlorosperma has led to the isolation and identification of a chalcone, dihydroglychalcone (1) and three sulphones - dambullin (2), sakambullin (3) and methylgerambullin (4), along with the common triterpene, stigmasterol. Compounds (1) (2) and (3) showed cytotoxic activity towards CEM-SS T-lymphoblastic cell lines. However, only dambullin (2) showed activity against pathogenic bacteria and fungi. We wish to report the isolation and bioassay results of the crude extracts and pure compounds. Faculty of Science, University of Malaya 2006-06 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/18299/1/Chemical%20constituents%20and%20biological%20activities%20of%20Glycosmis%20chlorosperma%20var.pdf Abdullah, Rosmiati and Rahmani, Mawardi and Ali, Abdul Manaf and Ismail, H.B.M. and Sukari, Mohd Aspollah and Lian, Gwendoline Ee Cheng (2006) Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae). Malaysian Journal of Science, 25 (1). pp. 45-51. ISSN 1394-3065 Glycosmis Plant bioactive compounds Antioxidants English |
| spellingShingle | Glycosmis Plant bioactive compounds Antioxidants Abdullah, Rosmiati Rahmani, Mawardi Ali, Abdul Manaf Ismail, H.B.M. Sukari, Mohd Aspollah Lian, Gwendoline Ee Cheng Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title | Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title_full | Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title_fullStr | Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title_full_unstemmed | Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title_short | Chemical constituents and biological activities of Glycosmis chlorosperma var. Elmeri (Merr.) stone (Rutaceae) |
| title_sort | chemical constituents and biological activities of glycosmis chlorosperma var. elmeri (merr.) stone (rutaceae) |
| topic | Glycosmis Plant bioactive compounds Antioxidants |
| url | http://psasir.upm.edu.my/id/eprint/18299/ http://psasir.upm.edu.my/id/eprint/18299/1/Chemical%20constituents%20and%20biological%20activities%20of%20Glycosmis%20chlorosperma%20var.pdf |