Haute couture: molecules and biocatalysts

For the next 50 years, chemistry will be just as fashionable as it has been in the past 50 years. In fact, the role of chemistry is bigger than ever with the help of bioinformatics that are riding the waves of genomic revolution. Bio-based processes and entities are becoming more organic with c...

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Main Author: Abdul Rahman, Mohd Basyaruddin
Format: Inaugural Lecture
Language:English
English
Published: Universiti Putra Malaysia Press 2010
Online Access:http://psasir.upm.edu.my/id/eprint/18245/
http://psasir.upm.edu.my/id/eprint/18245/1/Cover.pdf
http://psasir.upm.edu.my/id/eprint/18245/3/PROF%20BASYA.pdf
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author Abdul Rahman, Mohd Basyaruddin
author_facet Abdul Rahman, Mohd Basyaruddin
author_sort Abdul Rahman, Mohd Basyaruddin
building UPM Institutional Repository
collection Online Access
description For the next 50 years, chemistry will be just as fashionable as it has been in the past 50 years. In fact, the role of chemistry is bigger than ever with the help of bioinformatics that are riding the waves of genomic revolution. Bio-based processes and entities are becoming more organic with civilians requesting sustainable approaches to everything. Globally, the runway for the implementation of industrial biotechnology is nearly complete and is ready to overtake harsh chemical processes. However, major issues such as the high capital costs of advanced biocatalysts, organic solvent replacements and bioreactor technologies are the winding roads to progress. Research on enzymes and liquid engineering has brought us to new dimensions of understanding the unknown capabilities of unnatural enzyme systems at the molecular and atomic levels. The development of designer biocatalysts for industrial purposes to substitute traditional processes is gaining interest. Utilisation of local microbial enzymes and our tropical biodiversity for the discovery and identification of new biocatalysts through advanced structural and synthetic biology are the key focuses. In addition, bioinformatics or the in silico approach of designing novel single molecules to macromolecules is a powerful tool to model any mechanism and structure. By all accounts, the efficient use of bio-renewable resources requires blending different systems of chemistry and biology; heterogeneous and homogeneous, enzymes and metals, microbial and yeast, etc. This technology presents current and potential areas in which the use of a biocatalyst is a prerequisite for an economical application in green organic syntheses. Considering the industrial importance of the platform and fine chemicals, the optimal conditions for up scaling the process are evaluated by statistical methods while taking into consideration, all of the sustainable, environmental and economical evaluations. It will be essential for chemists or biological engineers to design and model the biocatalysts to significantly guide and quicken the steps for synthesising new molecules and improve existing systems. We need many new revolutionary molecules and biocatalysts for a plethora of chemical reactions and industrial applications.
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spelling upm-182452015-11-19T08:56:15Z http://psasir.upm.edu.my/id/eprint/18245/ Haute couture: molecules and biocatalysts Abdul Rahman, Mohd Basyaruddin For the next 50 years, chemistry will be just as fashionable as it has been in the past 50 years. In fact, the role of chemistry is bigger than ever with the help of bioinformatics that are riding the waves of genomic revolution. Bio-based processes and entities are becoming more organic with civilians requesting sustainable approaches to everything. Globally, the runway for the implementation of industrial biotechnology is nearly complete and is ready to overtake harsh chemical processes. However, major issues such as the high capital costs of advanced biocatalysts, organic solvent replacements and bioreactor technologies are the winding roads to progress. Research on enzymes and liquid engineering has brought us to new dimensions of understanding the unknown capabilities of unnatural enzyme systems at the molecular and atomic levels. The development of designer biocatalysts for industrial purposes to substitute traditional processes is gaining interest. Utilisation of local microbial enzymes and our tropical biodiversity for the discovery and identification of new biocatalysts through advanced structural and synthetic biology are the key focuses. In addition, bioinformatics or the in silico approach of designing novel single molecules to macromolecules is a powerful tool to model any mechanism and structure. By all accounts, the efficient use of bio-renewable resources requires blending different systems of chemistry and biology; heterogeneous and homogeneous, enzymes and metals, microbial and yeast, etc. This technology presents current and potential areas in which the use of a biocatalyst is a prerequisite for an economical application in green organic syntheses. Considering the industrial importance of the platform and fine chemicals, the optimal conditions for up scaling the process are evaluated by statistical methods while taking into consideration, all of the sustainable, environmental and economical evaluations. It will be essential for chemists or biological engineers to design and model the biocatalysts to significantly guide and quicken the steps for synthesising new molecules and improve existing systems. We need many new revolutionary molecules and biocatalysts for a plethora of chemical reactions and industrial applications. Universiti Putra Malaysia Press 2010 Inaugural Lecture NonPeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/18245/1/Cover.pdf application/pdf en http://psasir.upm.edu.my/id/eprint/18245/3/PROF%20BASYA.pdf Abdul Rahman, Mohd Basyaruddin (2010) Haute couture: molecules and biocatalysts. [Inaugural Lecture]
spellingShingle Abdul Rahman, Mohd Basyaruddin
Haute couture: molecules and biocatalysts
title Haute couture: molecules and biocatalysts
title_full Haute couture: molecules and biocatalysts
title_fullStr Haute couture: molecules and biocatalysts
title_full_unstemmed Haute couture: molecules and biocatalysts
title_short Haute couture: molecules and biocatalysts
title_sort haute couture: molecules and biocatalysts
url http://psasir.upm.edu.my/id/eprint/18245/
http://psasir.upm.edu.my/id/eprint/18245/1/Cover.pdf
http://psasir.upm.edu.my/id/eprint/18245/3/PROF%20BASYA.pdf