Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur

This study was carried out to macroscopically evaluate the ability of coral to repair a large size bone defect. A total 12 adult, male sheep were divided into 4 groups. The large bone defect (2.5 cm x 0.5 cm x 0.5 cm) was created surgically on the left proximal femur and replaced by a block of coral...

Full description

Bibliographic Details
Main Authors: Ahmad, Fadilah, Abu Bakar @ Zakaria, Md Zuki, Mohamad Yusof, Loqman, Saad, Mohd Zamri, Yusof, Norimah, Hassan, Asnah
Format: Article
Language:English
Published: Malaysian Medical Association 2004
Online Access:http://psasir.upm.edu.my/id/eprint/17989/
http://psasir.upm.edu.my/id/eprint/17989/1/Gross%2C%20radiology.pdf
_version_ 1848843395608346624
author Ahmad, Fadilah
Abu Bakar @ Zakaria, Md Zuki
Mohamad Yusof, Loqman
Saad, Mohd Zamri
Yusof, Norimah
Hassan, Asnah
author_facet Ahmad, Fadilah
Abu Bakar @ Zakaria, Md Zuki
Mohamad Yusof, Loqman
Saad, Mohd Zamri
Yusof, Norimah
Hassan, Asnah
author_sort Ahmad, Fadilah
building UPM Institutional Repository
collection Online Access
description This study was carried out to macroscopically evaluate the ability of coral to repair a large size bone defect. A total 12 adult, male sheep were divided into 4 groups. The large bone defect (2.5 cm x 0.5 cm x 0.5 cm) was created surgically on the left proximal femur and replaced by a block of coral (Porites sp.). Radiographs were obtained immediately after surgery and at 2, 4, 8 and 12 weeks postimplantation. Ultrasonographic examinations were carried out every 2 weeks after implantation up to 12 weeks using ultrasound machine (TOSHIBA Capasee II) connected with a 7-MHz frequency transducer. The sheep were euthanized at 2, 4, 8 and 12 weeks postimplantation and the bone was examined grossly. Both ultrasonographs and radiographs taken at 8 and 12 weeks showed that the implants had resorbed and left a space that was much reduced in size. There was no sign of implant rejection observed in all animals. The results showed that processed coral had potential to become bone substitute for reconstructive bone surgery.
first_indexed 2025-11-15T08:14:21Z
format Article
id upm-17989
institution Universiti Putra Malaysia
institution_category Local University
language English
last_indexed 2025-11-15T08:14:21Z
publishDate 2004
publisher Malaysian Medical Association
recordtype eprints
repository_type Digital Repository
spelling upm-179892016-11-21T01:10:12Z http://psasir.upm.edu.my/id/eprint/17989/ Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur Ahmad, Fadilah Abu Bakar @ Zakaria, Md Zuki Mohamad Yusof, Loqman Saad, Mohd Zamri Yusof, Norimah Hassan, Asnah This study was carried out to macroscopically evaluate the ability of coral to repair a large size bone defect. A total 12 adult, male sheep were divided into 4 groups. The large bone defect (2.5 cm x 0.5 cm x 0.5 cm) was created surgically on the left proximal femur and replaced by a block of coral (Porites sp.). Radiographs were obtained immediately after surgery and at 2, 4, 8 and 12 weeks postimplantation. Ultrasonographic examinations were carried out every 2 weeks after implantation up to 12 weeks using ultrasound machine (TOSHIBA Capasee II) connected with a 7-MHz frequency transducer. The sheep were euthanized at 2, 4, 8 and 12 weeks postimplantation and the bone was examined grossly. Both ultrasonographs and radiographs taken at 8 and 12 weeks showed that the implants had resorbed and left a space that was much reduced in size. There was no sign of implant rejection observed in all animals. The results showed that processed coral had potential to become bone substitute for reconstructive bone surgery. Malaysian Medical Association 2004 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17989/1/Gross%2C%20radiology.pdf Ahmad, Fadilah and Abu Bakar @ Zakaria, Md Zuki and Mohamad Yusof, Loqman and Saad, Mohd Zamri and Yusof, Norimah and Hassan, Asnah (2004) Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur. Medical Journal of Malaysia, 59 (supp.B). pp. 178-179. ISSN 0300-5283
spellingShingle Ahmad, Fadilah
Abu Bakar @ Zakaria, Md Zuki
Mohamad Yusof, Loqman
Saad, Mohd Zamri
Yusof, Norimah
Hassan, Asnah
Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title_full Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title_fullStr Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title_full_unstemmed Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title_short Gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
title_sort gross, radiology and ultrasonographic evaluation of coral post-implantation in sheep femur
url http://psasir.upm.edu.my/id/eprint/17989/
http://psasir.upm.edu.my/id/eprint/17989/1/Gross%2C%20radiology.pdf