Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages

Cassava leaves are good sources of protein which have a potential to substitute grain concentrate in livestock feed. However, a major constraint in using cassava fodder as animal feed is the presence of hydrogen cyanide (HCN). A study was conducted to compare the cumulative effects of thiocyanate (...

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Main Authors: Shaari, Mohd Rosly, Liang, Juan Boo, Mohamed Mustapha, Noordin, Somchit, Muhammad Nazrul Hakim, Mohd Jelan, Zainal Aznam
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2010
Online Access:http://psasir.upm.edu.my/id/eprint/17427/
http://psasir.upm.edu.my/id/eprint/17427/1/20%20Pg%20127-133.pdf
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author Shaari, Mohd Rosly
Liang, Juan Boo
Mohamed Mustapha, Noordin
Somchit, Muhammad Nazrul Hakim
Mohd Jelan, Zainal Aznam
author_facet Shaari, Mohd Rosly
Liang, Juan Boo
Mohamed Mustapha, Noordin
Somchit, Muhammad Nazrul Hakim
Mohd Jelan, Zainal Aznam
author_sort Shaari, Mohd Rosly
building UPM Institutional Repository
collection Online Access
description Cassava leaves are good sources of protein which have a potential to substitute grain concentrate in livestock feed. However, a major constraint in using cassava fodder as animal feed is the presence of hydrogen cyanide (HCN). A study was conducted to compare the cumulative effects of thiocyanate (a product from the detoxification of hydrogen cyanide) at 4 mg and 7 mg HCN/ kg body weight on sheep and goats. Thiocyanate was sourced from the detoxification of hydrogen cyanide in cassava. The tissue thiocyanate concentrations were found to be significantly (p<0.05) higher in liver (2.29 μg/mL/g tissue) of goats as compared to that of sheep. Meanwhile, histological examination of the liver revealed the presence of periportal necrosis. In spite of detoxification process of hydrogen cyanide to thiocyanate, it could be concluded that at 7 mg HCN/kg body weight, considerable amount of thiocyanate was retained in the body and accumulated in the liver.
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spelling upm-174272016-11-22T09:23:49Z http://psasir.upm.edu.my/id/eprint/17427/ Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages Shaari, Mohd Rosly Liang, Juan Boo Mohamed Mustapha, Noordin Somchit, Muhammad Nazrul Hakim Mohd Jelan, Zainal Aznam Cassava leaves are good sources of protein which have a potential to substitute grain concentrate in livestock feed. However, a major constraint in using cassava fodder as animal feed is the presence of hydrogen cyanide (HCN). A study was conducted to compare the cumulative effects of thiocyanate (a product from the detoxification of hydrogen cyanide) at 4 mg and 7 mg HCN/ kg body weight on sheep and goats. Thiocyanate was sourced from the detoxification of hydrogen cyanide in cassava. The tissue thiocyanate concentrations were found to be significantly (p<0.05) higher in liver (2.29 μg/mL/g tissue) of goats as compared to that of sheep. Meanwhile, histological examination of the liver revealed the presence of periportal necrosis. In spite of detoxification process of hydrogen cyanide to thiocyanate, it could be concluded that at 7 mg HCN/kg body weight, considerable amount of thiocyanate was retained in the body and accumulated in the liver. Universiti Putra Malaysia Press 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17427/1/20%20Pg%20127-133.pdf Shaari, Mohd Rosly and Liang, Juan Boo and Mohamed Mustapha, Noordin and Somchit, Muhammad Nazrul Hakim and Mohd Jelan, Zainal Aznam (2010) Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages. Pertanika Journal of Tropical Agricultural Science, 33 (1). pp. 127-133. ISSN 1511-3701; ESSN: 2231-8542 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JTAS%20Vol.%2033%20(1)%20Feb.%202010/20%20Pg%20127-133.pdf
spellingShingle Shaari, Mohd Rosly
Liang, Juan Boo
Mohamed Mustapha, Noordin
Somchit, Muhammad Nazrul Hakim
Mohd Jelan, Zainal Aznam
Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title_full Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title_fullStr Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title_full_unstemmed Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title_short Tissues thiocyanate (SCN) concentration and liver pathology of sheep and goats fed on cassava forages
title_sort tissues thiocyanate (scn) concentration and liver pathology of sheep and goats fed on cassava forages
url http://psasir.upm.edu.my/id/eprint/17427/
http://psasir.upm.edu.my/id/eprint/17427/
http://psasir.upm.edu.my/id/eprint/17427/1/20%20Pg%20127-133.pdf