The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
Objective: To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice. Methods: A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English English |
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IOS Press
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/17313/ http://psasir.upm.edu.my/id/eprint/17313/1/The%20role%20of%20antenatal%20vitamin%20e%20supplementation%20in%20the%20prevention%20of%20neonatal%20jaundice.pdf |
| _version_ | 1848843207102693376 |
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| author | Jaafar, Rohana Abdullah Mahdy, Zaleha Siraj, Harlina Halizah Khaza'ai , Huzwah Abd Mutalib, Mohd Sokhini Mohd Dali, Ahmad Zailani Hatta |
| author_facet | Jaafar, Rohana Abdullah Mahdy, Zaleha Siraj, Harlina Halizah Khaza'ai , Huzwah Abd Mutalib, Mohd Sokhini Mohd Dali, Ahmad Zailani Hatta |
| author_sort | Jaafar, Rohana |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Objective:
To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice.
Methods:
A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks gestation until delivery, primigravida mothers with singleton pregnancies received either 100 mg daily vitamin E in the form of tocotrienol rich fraction, or placebo. The newborns were assessed for jaundice.
Results:
Among 262 infants, 136 were in the vitamin E group and 126 in the placebo group. The incidence of neonatal jaundice was similar: 38% (54/136) in the vitamin E group and 36% (45/126) in the placebo group (p= 0.10). Nevertheless, the vitamin E group had a tendency for lower peak serum bilirubin, although not significantly so.
Conclusion:
Maternal antenatal vitamin E supplementation had no effect on the incidence of neonatal jaundice. |
| first_indexed | 2025-11-15T08:11:21Z |
| format | Article |
| id | upm-17313 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:11:21Z |
| publishDate | 2010 |
| publisher | IOS Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-173132015-10-08T08:12:42Z http://psasir.upm.edu.my/id/eprint/17313/ The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice. Jaafar, Rohana Abdullah Mahdy, Zaleha Siraj, Harlina Halizah Khaza'ai , Huzwah Abd Mutalib, Mohd Sokhini Mohd Dali, Ahmad Zailani Hatta Objective: To determine the effect of maternal antenatal vitamin E supplementation on neonatal jaundice. Methods: A randomized double blind controlled trial assessing the role of vitamin E in the prevention of preeclampsia was conducted in a tertiary hospital over two years. From 12-16 weeks gestation until delivery, primigravida mothers with singleton pregnancies received either 100 mg daily vitamin E in the form of tocotrienol rich fraction, or placebo. The newborns were assessed for jaundice. Results: Among 262 infants, 136 were in the vitamin E group and 126 in the placebo group. The incidence of neonatal jaundice was similar: 38% (54/136) in the vitamin E group and 36% (45/126) in the placebo group (p= 0.10). Nevertheless, the vitamin E group had a tendency for lower peak serum bilirubin, although not significantly so. Conclusion: Maternal antenatal vitamin E supplementation had no effect on the incidence of neonatal jaundice. IOS Press 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17313/1/The%20role%20of%20antenatal%20vitamin%20e%20supplementation%20in%20the%20prevention%20of%20neonatal%20jaundice.pdf Jaafar, Rohana and Abdullah Mahdy, Zaleha and Siraj, Harlina Halizah and Khaza'ai , Huzwah and Abd Mutalib, Mohd Sokhini and Mohd Dali, Ahmad Zailani Hatta (2010) The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice. Journal of Neonatal-Perinatal Medicine, 3 (3). pp. 217-221. ISSN 1934-5798, EISSN: 1878-4429 http://www.iospress.nl Jaundice, Neonatal. Vitamin E. Newborn infants - Diseases. 10.3233/NPM-2010-0118 English |
| spellingShingle | Jaundice, Neonatal. Vitamin E. Newborn infants - Diseases. Jaafar, Rohana Abdullah Mahdy, Zaleha Siraj, Harlina Halizah Khaza'ai , Huzwah Abd Mutalib, Mohd Sokhini Mohd Dali, Ahmad Zailani Hatta The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice. |
| title | The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
|
| title_full | The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
|
| title_fullStr | The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
|
| title_full_unstemmed | The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
|
| title_short | The role of antenatal vitamin e supplementation in the prevention of neonatal jaundice.
|
| title_sort | role of antenatal vitamin e supplementation in the prevention of neonatal jaundice. |
| topic | Jaundice, Neonatal. Vitamin E. Newborn infants - Diseases. |
| url | http://psasir.upm.edu.my/id/eprint/17313/ http://psasir.upm.edu.my/id/eprint/17313/ http://psasir.upm.edu.my/id/eprint/17313/ http://psasir.upm.edu.my/id/eprint/17313/1/The%20role%20of%20antenatal%20vitamin%20e%20supplementation%20in%20the%20prevention%20of%20neonatal%20jaundice.pdf |