Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.)
Phaleria macrocarpa (Scheff.) Boerl known as Mahkota Dewa is one of Indonesia's traditional medicines from family of Thymelaeaceae. Traditional medicine practitioners claim that the chemical compounds in mahkota dewa retains antihistamine, antioxidant and anti cancer effects. In this study, one...
| Main Authors: | , , , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
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UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/17166/ http://psasir.upm.edu.my/id/eprint/17166/1/ABSTRACT%20CAC%202014_2%20medic%2015.pdf |
| _version_ | 1848843166763974656 |
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| author | Ismail, Adawiah Abdullah, Luqman Chuah Pin, Kar Yong Awang Biak, Dayang Radiah Yusuf, Umi Kalsom Ismail, Nor Fariza |
| author_facet | Ismail, Adawiah Abdullah, Luqman Chuah Pin, Kar Yong Awang Biak, Dayang Radiah Yusuf, Umi Kalsom Ismail, Nor Fariza |
| author_sort | Ismail, Adawiah |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Phaleria macrocarpa (Scheff.) Boerl known as Mahkota Dewa is one of Indonesia's traditional medicines from family of Thymelaeaceae. Traditional medicine practitioners claim that the chemical compounds in mahkota dewa retains antihistamine, antioxidant and anti cancer effects. In this study, one compound has been successfully isolated from methanolic extract of Mahkota Dewa's fruit as single compound known as mangiferin. To ensure whether this compound; mangiferin contribute to the anti cancer activities, the cytotoxic effect on a breast cancer cell line; MCF-7, cervical cancer cell line; HeLa, and human colon adenocarcinoma cell; HT-29, was examined. The results show that Mahkota Dewa can be promising sources of natural products with potential anti cancer. |
| first_indexed | 2025-11-15T08:10:43Z |
| format | Conference or Workshop Item |
| id | upm-17166 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:10:43Z |
| publishDate | 2014 |
| publisher | UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-171662016-04-26T04:09:51Z http://psasir.upm.edu.my/id/eprint/17166/ Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) Ismail, Adawiah Abdullah, Luqman Chuah Pin, Kar Yong Awang Biak, Dayang Radiah Yusuf, Umi Kalsom Ismail, Nor Fariza Phaleria macrocarpa (Scheff.) Boerl known as Mahkota Dewa is one of Indonesia's traditional medicines from family of Thymelaeaceae. Traditional medicine practitioners claim that the chemical compounds in mahkota dewa retains antihistamine, antioxidant and anti cancer effects. In this study, one compound has been successfully isolated from methanolic extract of Mahkota Dewa's fruit as single compound known as mangiferin. To ensure whether this compound; mangiferin contribute to the anti cancer activities, the cytotoxic effect on a breast cancer cell line; MCF-7, cervical cancer cell line; HeLa, and human colon adenocarcinoma cell; HT-29, was examined. The results show that Mahkota Dewa can be promising sources of natural products with potential anti cancer. UPM-MAKNA Cancer Research Laboratory, Institute of Bioscience 2014 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/17166/1/ABSTRACT%20CAC%202014_2%20medic%2015.pdf Ismail, Adawiah and Abdullah, Luqman Chuah and Pin, Kar Yong and Awang Biak, Dayang Radiah and Yusuf, Umi Kalsom and Ismail, Nor Fariza (2014) Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.). In: Scientific Cancer Research Poster Competition in conjunction with Cancer Awareness Carnival 2014, 10 May 2014, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia. . |
| spellingShingle | Ismail, Adawiah Abdullah, Luqman Chuah Pin, Kar Yong Awang Biak, Dayang Radiah Yusuf, Umi Kalsom Ismail, Nor Fariza Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title | Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title_full | Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title_fullStr | Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title_full_unstemmed | Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title_short | Anti cancer activity of mangiferin from methanol extract of fruit of Mahkota Dewa (Phaleria macrocarpa (Scheff.) Boerl.) |
| title_sort | anti cancer activity of mangiferin from methanol extract of fruit of mahkota dewa (phaleria macrocarpa (scheff.) boerl.) |
| url | http://psasir.upm.edu.my/id/eprint/17166/ http://psasir.upm.edu.my/id/eprint/17166/1/ABSTRACT%20CAC%202014_2%20medic%2015.pdf |