Thalassemia intermedia in HbH-CS disease with compound heterozygosity for β-thalassemia: challenges in hemoglobin analysis and clinical diagnosis

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Thalassemia intermedia in HbH-CS disease with compound heterozygosity for β-thalassemia: challenges in hemoglobin analysis and clinical diagnosis

Co-inheritance of α-thalassemia with homozygosity or compound heterozygosity for β-thalassemia may ameliorate β-thalassemia major. A wide range of clinical phenotypes is produced depending on the number of α-thalassemia alleles (-α/αα --/αα, --/-α). The co-inheritance of β-thalassemia with α-thalass...

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Bibliographic Details
Main Authors:	Tan, Mary Anne Jin Ai, Kok, Juan Loong, Tan, Kim Lian, Wee, Yong Chui, George, Elizabeth
Format:	Article
Language:	English
Published:	The Genetics Society of Japan 2009
Online Access:	http://psasir.upm.edu.my/id/eprint/17004/ http://psasir.upm.edu.my/id/eprint/17004/1/Thalassemia%20intermedia%20in%20HbH.pdf

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