Oral vaccine of Lactococcus lactis harbouring pandemic H1N1 2009 haemagglutinin1 and nisP anchor fusion protein elevates anti-HA1 sIgA levels in mice

Oral vaccine of Lactococcus lactis harbouring pandemic H1N1 2009 haemagglutinin1 and nisP anchor fusion protein elevates anti-HA1 sIgA levels in mice

Objective: An oral lactococcal-based vaccine which haboured the haemagglutinin1 (HA1) antigen fused to nisP anchor protein for the purpose of surface displaying the HA1 antigen was developed against H1N1 virus. Results: Recombinant L. lactis strains expressed HA1-nisP fusion proteins when induced wi...

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Bibliographic Details
Main Authors: Siaw, Stella Xiu Joan, Jee, Pui Fong, Song, Adelene Ai Lian, Chang, Li Yen, Yusoff, Khatijah, Abu Bakar, Sazaly, Abdul Rahim, Raha
Format: Article
Language:English
Published: Springer 2016
Online Access:http://psasir.upm.edu.my/id/eprint/16997/
http://psasir.upm.edu.my/id/eprint/16997/1/Oral%20vaccine%20of%20Lactococcus%20lactis%20harbouring%20pandemic%20H1N1%202009%20haemagglutinin1%20and%20nisP%20anchor%20fusion%20protein%20elevates%20anti-HA1%20sIgA%20levels%20in%20mice.pdf

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