Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca)
The bioactive flavonoid compounds of Strobilanthes crispus (Pecah Kaca) leaves obtained by using supercritical carbon dioxide (SC-CO2) extraction were investigated and the obtained crude extract yields were compared in order to select the best operation parameters. Since carbon dioxide is a non-pola...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16894/ http://psasir.upm.edu.my/id/eprint/16894/1/Supercritical%20carbon%20dioxide%20extraction%20of%20bioactive%20flavonoid%20from%20strobilanthes%20crispus%20%28Pecah%20Kaca%29.pdf |
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| author | Md Salleh, Liza Abdul Rahman, Russly Bimakr, Mandana Selamat, Jinap Rahmat, Asmah Sarker, Md. Zaidul Islam Abdul Hamid, Azizah |
| author_facet | Md Salleh, Liza Abdul Rahman, Russly Bimakr, Mandana Selamat, Jinap Rahmat, Asmah Sarker, Md. Zaidul Islam Abdul Hamid, Azizah |
| author_sort | Md Salleh, Liza |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | The bioactive flavonoid compounds of Strobilanthes crispus (Pecah Kaca) leaves obtained by using supercritical carbon dioxide (SC-CO2) extraction were investigated and the obtained crude extract yields were compared in order to select the best operation parameters. Since carbon dioxide is a non-polar solvent, ethanol was used as co-solvent to increase the polarity of the fluid. The studied parameters were pressure (100, 150 and 200 bar), temperature (40, 50 and 60 °C) and dynamic extraction time (40, 60 and 80 min). The optimum extraction condition occurred at 200 bar, 50 °C and 60 min. Based on the mean value, pressure had dominant effect on the extraction yield. Apart from the optimum SFE conditions two other conditions namely at minimum (100 bar, 40 °C, 40 min) and maximum (200 bar, 60 °C, 80 min) levels of each studied parameters as control runs were analyzed by HPLC to determine the major bioactive flavonoid compounds from S. crispus. Under the optimum conditions eight flavonoid compounds were identified; they were (+)-catechin, (−)-epicatechin, rutin, myricetin, luteolin, apigenin, naringenin and kaempferol. |
| first_indexed | 2025-11-15T08:09:29Z |
| format | Article |
| id | upm-16894 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:09:29Z |
| publishDate | 2010 |
| publisher | Elsevier |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-168942016-11-25T09:27:17Z http://psasir.upm.edu.my/id/eprint/16894/ Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) Md Salleh, Liza Abdul Rahman, Russly Bimakr, Mandana Selamat, Jinap Rahmat, Asmah Sarker, Md. Zaidul Islam Abdul Hamid, Azizah The bioactive flavonoid compounds of Strobilanthes crispus (Pecah Kaca) leaves obtained by using supercritical carbon dioxide (SC-CO2) extraction were investigated and the obtained crude extract yields were compared in order to select the best operation parameters. Since carbon dioxide is a non-polar solvent, ethanol was used as co-solvent to increase the polarity of the fluid. The studied parameters were pressure (100, 150 and 200 bar), temperature (40, 50 and 60 °C) and dynamic extraction time (40, 60 and 80 min). The optimum extraction condition occurred at 200 bar, 50 °C and 60 min. Based on the mean value, pressure had dominant effect on the extraction yield. Apart from the optimum SFE conditions two other conditions namely at minimum (100 bar, 40 °C, 40 min) and maximum (200 bar, 60 °C, 80 min) levels of each studied parameters as control runs were analyzed by HPLC to determine the major bioactive flavonoid compounds from S. crispus. Under the optimum conditions eight flavonoid compounds were identified; they were (+)-catechin, (−)-epicatechin, rutin, myricetin, luteolin, apigenin, naringenin and kaempferol. Elsevier 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16894/1/Supercritical%20carbon%20dioxide%20extraction%20of%20bioactive%20flavonoid%20from%20strobilanthes%20crispus%20%28Pecah%20Kaca%29.pdf Md Salleh, Liza and Abdul Rahman, Russly and Bimakr, Mandana and Selamat, Jinap and Rahmat, Asmah and Sarker, Md. Zaidul Islam and Abdul Hamid, Azizah (2010) Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca). Food and Bioproducts Processing, 88 (2-3). pp. 319-326. ISSN 0960-3085; ESSN: 1744-3571 10.1016/j.fbp.2009.02.001 |
| spellingShingle | Md Salleh, Liza Abdul Rahman, Russly Bimakr, Mandana Selamat, Jinap Rahmat, Asmah Sarker, Md. Zaidul Islam Abdul Hamid, Azizah Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title | Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title_full | Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title_fullStr | Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title_full_unstemmed | Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title_short | Supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (Pecah Kaca) |
| title_sort | supercritical carbon dioxide extraction of bioactive flavonoid from strobilanthes crispus (pecah kaca) |
| url | http://psasir.upm.edu.my/id/eprint/16894/ http://psasir.upm.edu.my/id/eprint/16894/ http://psasir.upm.edu.my/id/eprint/16894/1/Supercritical%20carbon%20dioxide%20extraction%20of%20bioactive%20flavonoid%20from%20strobilanthes%20crispus%20%28Pecah%20Kaca%29.pdf |