Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same phylum (Apicomplexa) as several human and animal parasites such as Cryptosporidium, Toxoplasma, and t...
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| Format: | Article |
| Language: | English English |
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Cold Spring Harbor Laboratory Press
2007
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16675/ http://psasir.upm.edu.my/id/eprint/16675/1/Sequencing%20and%20analysis%20of%20chromosome%201%20of%20Eimeria%20tenella%20reveals%20a%20unique%20segmental%20organization.pdf |
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| author | Ling , King Hwa Rajandream, Marie Adèle Rivailler, Pierre Ivens, Alasdair C. Yap, Soon J. Madeira, Alda Maria Backx Noronha Mungall, Karen L. Billington, Karen J. Yee, Wai Y. Bankier, Alan T. Carroll, Fionnadh Durham, Alan Mitchell Peters, Nick T. Loo, Shu S. Isa, M. N M Novaes, Jeniffer Quail, Michael A. Rosli, Rozita Shamsudin, Mariana Nor Sobreira, Tiago José Pascoal Tivey, Adrian R. Wai, Siew F. White, Sarah E. Wu, Xikun Kerhornou, Arnaud X. Blake, Damer P. Mohamed, Rahmah I. Shirley, Martin W. Gruber, Arthur Berriman, Matthew Tomley, Fiona M Fiona Dear, Paul H. Wan, Kiew Lian |
| author_facet | Ling , King Hwa Rajandream, Marie Adèle Rivailler, Pierre Ivens, Alasdair C. Yap, Soon J. Madeira, Alda Maria Backx Noronha Mungall, Karen L. Billington, Karen J. Yee, Wai Y. Bankier, Alan T. Carroll, Fionnadh Durham, Alan Mitchell Peters, Nick T. Loo, Shu S. Isa, M. N M Novaes, Jeniffer Quail, Michael A. Rosli, Rozita Shamsudin, Mariana Nor Sobreira, Tiago José Pascoal Tivey, Adrian R. Wai, Siew F. White, Sarah E. Wu, Xikun Kerhornou, Arnaud X. Blake, Damer P. Mohamed, Rahmah I. Shirley, Martin W. Gruber, Arthur Berriman, Matthew Tomley, Fiona M Fiona Dear, Paul H. Wan, Kiew Lian |
| author_sort | Ling , King Hwa |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same phylum (Apicomplexa) as several human and animal parasites such as Cryptosporidium, Toxoplasma, and the malaria parasite, Plasmodium. Here we report the sequencing and analysis of the first chromosome of E. tenella, a chromosome believed to carry loci associated with drug resistance and known to differ between virulent and attenuated strains of the parasite. The chromosome - which appears to be representative of the genome - is gene-dense and rich in simple-sequence repeats, many of which appear to give rise to repetitive amino acid tracts in the predicted proteins. Most striking is the segmentation of the chromosome into repeat-rich regions peppered with transposon-like elements and telomere-like repeats, alternating with repeat-free regions. Predicted genes differ in character between the two types of segment, and the repeat-rich regions appear to be associated with strain-to-strain variation. |
| first_indexed | 2025-11-15T08:08:30Z |
| format | Article |
| id | upm-16675 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:08:30Z |
| publishDate | 2007 |
| publisher | Cold Spring Harbor Laboratory Press |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-166752015-10-05T08:34:46Z http://psasir.upm.edu.my/id/eprint/16675/ Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization. Ling , King Hwa Rajandream, Marie Adèle Rivailler, Pierre Ivens, Alasdair C. Yap, Soon J. Madeira, Alda Maria Backx Noronha Mungall, Karen L. Billington, Karen J. Yee, Wai Y. Bankier, Alan T. Carroll, Fionnadh Durham, Alan Mitchell Peters, Nick T. Loo, Shu S. Isa, M. N M Novaes, Jeniffer Quail, Michael A. Rosli, Rozita Shamsudin, Mariana Nor Sobreira, Tiago José Pascoal Tivey, Adrian R. Wai, Siew F. White, Sarah E. Wu, Xikun Kerhornou, Arnaud X. Blake, Damer P. Mohamed, Rahmah I. Shirley, Martin W. Gruber, Arthur Berriman, Matthew Tomley, Fiona M Fiona Dear, Paul H. Wan, Kiew Lian Eimeria tenella is an intracellular protozoan parasite that infects the intestinal tracts of domestic fowl and causes coccidiosis, a serious and sometimes lethal enteritis. Eimeria falls in the same phylum (Apicomplexa) as several human and animal parasites such as Cryptosporidium, Toxoplasma, and the malaria parasite, Plasmodium. Here we report the sequencing and analysis of the first chromosome of E. tenella, a chromosome believed to carry loci associated with drug resistance and known to differ between virulent and attenuated strains of the parasite. The chromosome - which appears to be representative of the genome - is gene-dense and rich in simple-sequence repeats, many of which appear to give rise to repetitive amino acid tracts in the predicted proteins. Most striking is the segmentation of the chromosome into repeat-rich regions peppered with transposon-like elements and telomere-like repeats, alternating with repeat-free regions. Predicted genes differ in character between the two types of segment, and the repeat-rich regions appear to be associated with strain-to-strain variation. Cold Spring Harbor Laboratory Press 2007-03 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16675/1/Sequencing%20and%20analysis%20of%20chromosome%201%20of%20Eimeria%20tenella%20reveals%20a%20unique%20segmental%20organization.pdf Ling , King Hwa and Rajandream, Marie Adèle and Rivailler, Pierre and Ivens, Alasdair C. and Yap, Soon J. and Madeira, Alda Maria Backx Noronha and Mungall, Karen L. and Billington, Karen J. and Yee, Wai Y. and Bankier, Alan T. and Carroll, Fionnadh and Durham, Alan Mitchell and Peters, Nick T. and Loo, Shu S. and Isa, M. N M and Novaes, Jeniffer and Quail, Michael A. and Rosli, Rozita and Shamsudin, Mariana Nor and Sobreira, Tiago José Pascoal and Tivey, Adrian R. and Wai, Siew F. and White, Sarah E. and Wu, Xikun and Kerhornou, Arnaud X. and Blake, Damer P. and Mohamed, Rahmah I. and Shirley, Martin W. and Gruber, Arthur and Berriman, Matthew and Tomley, Fiona M Fiona and Dear, Paul H. and Wan, Kiew Lian (2007) Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization. Genome Research , 17 (3). pp. 311-319. ISSN 1088-9051, ESSN: 1549-5469 http://genome.cshlp.org/ Parasitic diseases. Medical parasitology. 10.1101/gr.5823007 English |
| spellingShingle | Parasitic diseases. Medical parasitology. Ling , King Hwa Rajandream, Marie Adèle Rivailler, Pierre Ivens, Alasdair C. Yap, Soon J. Madeira, Alda Maria Backx Noronha Mungall, Karen L. Billington, Karen J. Yee, Wai Y. Bankier, Alan T. Carroll, Fionnadh Durham, Alan Mitchell Peters, Nick T. Loo, Shu S. Isa, M. N M Novaes, Jeniffer Quail, Michael A. Rosli, Rozita Shamsudin, Mariana Nor Sobreira, Tiago José Pascoal Tivey, Adrian R. Wai, Siew F. White, Sarah E. Wu, Xikun Kerhornou, Arnaud X. Blake, Damer P. Mohamed, Rahmah I. Shirley, Martin W. Gruber, Arthur Berriman, Matthew Tomley, Fiona M Fiona Dear, Paul H. Wan, Kiew Lian Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization. |
| title | Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
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| title_full | Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
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| title_fullStr | Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
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| title_full_unstemmed | Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
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| title_short | Sequencing and analysis of chromosome 1 of Eimeria tenella reveals a unique segmental organization.
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| title_sort | sequencing and analysis of chromosome 1 of eimeria tenella reveals a unique segmental organization. |
| topic | Parasitic diseases. Medical parasitology. |
| url | http://psasir.upm.edu.my/id/eprint/16675/ http://psasir.upm.edu.my/id/eprint/16675/ http://psasir.upm.edu.my/id/eprint/16675/ http://psasir.upm.edu.my/id/eprint/16675/1/Sequencing%20and%20analysis%20of%20chromosome%201%20of%20Eimeria%20tenella%20reveals%20a%20unique%20segmental%20organization.pdf |