Secondary metabolites from two garcinia species and their biological activities.
Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy-2-(3-methylbut-2-enyl)xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garcin...
| Main Authors: | , |
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| Format: | Article |
| Language: | English English |
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Chemical Publishing Co.
2008
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16636/ http://psasir.upm.edu.my/id/eprint/16636/1/Secondary%20metabolites%20from%20two%20garcinia%20species%20and%20their%20biological%20activities.pdf |
| _version_ | 1848843016623620096 |
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| author | Ee, Gwendoline Cheng Lian Yuen, Lin Cheow |
| author_facet | Ee, Gwendoline Cheng Lian Yuen, Lin Cheow |
| author_sort | Ee, Gwendoline Cheng Lian |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy-2-(3-methylbut-2-enyl)xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garcinia parvifolia have afforded one triterpenoid, α-amyrin and two xanthones, cowanin and rubraxanthone. Their structures were derived based on spectroscopic evidence, mainly 1D and 2D NMR spectroscopy. Acetylation reaction was carried out on rubraxanthone to yield triacetate rubraxanthone. It was found that the pure rubraxanthone was strongly active against the larvae of Aedes aegypti with LC50 value of 15.49 μg/mL and HL-60 cell line with an IC50 value of 7.5 μg/mL.
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| first_indexed | 2025-11-15T08:08:19Z |
| format | Article |
| id | upm-16636 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English English |
| last_indexed | 2025-11-15T08:08:19Z |
| publishDate | 2008 |
| publisher | Chemical Publishing Co. |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-166362015-09-14T08:25:05Z http://psasir.upm.edu.my/id/eprint/16636/ Secondary metabolites from two garcinia species and their biological activities. Ee, Gwendoline Cheng Lian Yuen, Lin Cheow Detail chemical studies on Garcinia maingayi have yielded one xanthone, 1,3,7-trihydroxy-2-(3-methylbut-2-enyl)xanthone, one benzophenone, isoxanthochymol, one benzoic acid derivative 3,4-dihydroxy-methylbenzoate and two triterpenoids, stigmasterol and sitosterol. Meanwhile, investigations on Garcinia parvifolia have afforded one triterpenoid, α-amyrin and two xanthones, cowanin and rubraxanthone. Their structures were derived based on spectroscopic evidence, mainly 1D and 2D NMR spectroscopy. Acetylation reaction was carried out on rubraxanthone to yield triacetate rubraxanthone. It was found that the pure rubraxanthone was strongly active against the larvae of Aedes aegypti with LC50 value of 15.49 μg/mL and HL-60 cell line with an IC50 value of 7.5 μg/mL. Chemical Publishing Co. 2008-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16636/1/Secondary%20metabolites%20from%20two%20garcinia%20species%20and%20their%20biological%20activities.pdf Ee, Gwendoline Cheng Lian and Yuen, Lin Cheow (2008) Secondary metabolites from two garcinia species and their biological activities. Asian Journal of Chemistry, 20 (1). pp. 343-351. ISSN 0970-7077 English |
| spellingShingle | Ee, Gwendoline Cheng Lian Yuen, Lin Cheow Secondary metabolites from two garcinia species and their biological activities. |
| title | Secondary metabolites from two garcinia species and their biological activities. |
| title_full | Secondary metabolites from two garcinia species and their biological activities. |
| title_fullStr | Secondary metabolites from two garcinia species and their biological activities. |
| title_full_unstemmed | Secondary metabolites from two garcinia species and their biological activities. |
| title_short | Secondary metabolites from two garcinia species and their biological activities. |
| title_sort | secondary metabolites from two garcinia species and their biological activities. |
| url | http://psasir.upm.edu.my/id/eprint/16636/ http://psasir.upm.edu.my/id/eprint/16636/1/Secondary%20metabolites%20from%20two%20garcinia%20species%20and%20their%20biological%20activities.pdf |