Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes

Brushite (BR) and hydroxyapatite (HA) nanoparticles were fabricated through reverse microemulsion and hydrothermal processing route, respectively. The processing routes influenced nucleation and crystal growth although both methods resulted in nanorods formation. The calcium-to-phosphate ratio was 1...

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Main Authors: Lim, Hong Ngee, Kassim, Anuar, Huang, Nay Ming
Format: Article
Language:English
Published: Penerbit Universiti Kebangsaan Malaysia 2010
Online Access:http://psasir.upm.edu.my/id/eprint/16307/
http://psasir.upm.edu.my/id/eprint/16307/1/Preparation%20and%20characterization%20of%20Calcium%20phosphate%20nanorods%20using%20reverse%20microemulsion%20and%20hydrothermal%20processing%20routes.pdf
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author Lim, Hong Ngee
Kassim, Anuar
Huang, Nay Ming
author_facet Lim, Hong Ngee
Kassim, Anuar
Huang, Nay Ming
author_sort Lim, Hong Ngee
building UPM Institutional Repository
collection Online Access
description Brushite (BR) and hydroxyapatite (HA) nanoparticles were fabricated through reverse microemulsion and hydrothermal processing route, respectively. The processing routes influenced nucleation and crystal growth although both methods resulted in nanorods formation. The calcium-to-phosphate ratio was 1.67, similar to that of natural bone and teeth. X-ray diffraction patterns revealed that the nanorods possessed almost pure crystal phase with negligible second phase. The ratio of particle length-to-width of BR and HA were approximately 3 and 4, respectively. To mimic the natural bone, chitosan/brushite (CTS/BR) and chitosan/hydroxyapatite (CTS/HA) nanocomposite scaffolds were prepared through rapid freeze-drying technique. The compressive strength of CTS/BR and CTS/HA nanocomposite scaffolds was compared for the first time. The compression test revealed that both the nanocomposite scaffolds exhibited reasonably high compressive strength of approximately 7 MPa. This value falls in the high-end range of cancellous bone’s compressive strength, with the compressive strength of CTS/HA 0.88 MPa more than CTS/BR.
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spelling upm-163072016-03-16T02:07:29Z http://psasir.upm.edu.my/id/eprint/16307/ Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes Lim, Hong Ngee Kassim, Anuar Huang, Nay Ming Brushite (BR) and hydroxyapatite (HA) nanoparticles were fabricated through reverse microemulsion and hydrothermal processing route, respectively. The processing routes influenced nucleation and crystal growth although both methods resulted in nanorods formation. The calcium-to-phosphate ratio was 1.67, similar to that of natural bone and teeth. X-ray diffraction patterns revealed that the nanorods possessed almost pure crystal phase with negligible second phase. The ratio of particle length-to-width of BR and HA were approximately 3 and 4, respectively. To mimic the natural bone, chitosan/brushite (CTS/BR) and chitosan/hydroxyapatite (CTS/HA) nanocomposite scaffolds were prepared through rapid freeze-drying technique. The compressive strength of CTS/BR and CTS/HA nanocomposite scaffolds was compared for the first time. The compression test revealed that both the nanocomposite scaffolds exhibited reasonably high compressive strength of approximately 7 MPa. This value falls in the high-end range of cancellous bone’s compressive strength, with the compressive strength of CTS/HA 0.88 MPa more than CTS/BR. Penerbit Universiti Kebangsaan Malaysia 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16307/1/Preparation%20and%20characterization%20of%20Calcium%20phosphate%20nanorods%20using%20reverse%20microemulsion%20and%20hydrothermal%20processing%20routes.pdf Lim, Hong Ngee and Kassim, Anuar and Huang, Nay Ming (2010) Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes. Sains Malaysiana, 39 (2). pp. 267-273. ISSN 0126-6039 http://www.ukm.my/jsm/english_journals/vol39num2_2010/vol39num2_2010pg267-273.html
spellingShingle Lim, Hong Ngee
Kassim, Anuar
Huang, Nay Ming
Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title_full Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title_fullStr Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title_full_unstemmed Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title_short Preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
title_sort preparation and characterization of calcium phosphate nanorods using reverse microemulsion and hydrothermal processing routes
url http://psasir.upm.edu.my/id/eprint/16307/
http://psasir.upm.edu.my/id/eprint/16307/
http://psasir.upm.edu.my/id/eprint/16307/1/Preparation%20and%20characterization%20of%20Calcium%20phosphate%20nanorods%20using%20reverse%20microemulsion%20and%20hydrothermal%20processing%20routes.pdf