Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.

Estrogens (17 B-estradiol and estrone) concentrations in river and estuarine waters around Kuala Lumpur, Malaysia were determined by enzyme-linked immunosorbent assay while estrogenic potential of the waters were ascertained by three in vitro bioassays, namely E-screen, Ishikawa cell-alkaline phosp...

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Main Authors:	Koyama, Jiro, Imai, Shoko, Fujii, Kazunori, Kawai , Shin-ichiro, Yap, Chee Kong, Ismail, Ahmad
Format:	Article
Language:	English English
Published:	The Japanese Society of Environmental Toxicology 2006
Online Access:	http://psasir.upm.edu.my/id/eprint/16237/ http://psasir.upm.edu.my/id/eprint/16237/1/Pollution%20by%20estrogens%20in%20river%20and%20estuarine%20waters%20around%20Kuala%20Lumpur.pdf

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author	Koyama, Jiro Imai, Shoko Fujii, Kazunori Kawai , Shin-ichiro Yap, Chee Kong Ismail, Ahmad
author_facet	Koyama, Jiro Imai, Shoko Fujii, Kazunori Kawai , Shin-ichiro Yap, Chee Kong Ismail, Ahmad
author_sort	Koyama, Jiro
building	UPM Institutional Repository
collection	Online Access
description	Estrogens (17 B-estradiol and estrone) concentrations in river and estuarine waters around Kuala Lumpur, Malaysia were determined by enzyme-linked immunosorbent assay while estrogenic potential of the waters were ascertained by three in vitro bioassays, namely E-screen, Ishikawa cell-alkaline phosphatase and yeast estrogen screen. Moreover, hepatic vitellogenin, a precursor of yolk protein that is specific to females, were examined in male and female Java-medaka collected in the same area. 17B-estradiol and estrone concentrations were less than 6.1 ng/L and 127 ng/L, respectively. The highest 17B-estradiol equivalent activity, 284 ng/L, was detected by in vitro assay in Sungai Kuyoh, which was adjacent to a sewage plant. 17B-estradiol and estrone concentrations were not equal to their estrogenic potentials determined by in vitro assay implying the presence of other estrogenic chemicals in these waters. Hepatic vitellogenin concentrations of both male and female java-medaka were the same to laboratory-cultured individuals. Although relatively high estrogen concentrations were detected in some waters of Malaysia, these were not high enough to induce hepatic vitellogenin in male fishes. Further research, however, is necessary to cover more number of sampling sites.
first_indexed	2025-11-15T08:06:32Z
format	Article
id	upm-16237
institution	Universiti Putra Malaysia
institution_category	Local University
language	English English
last_indexed	2025-11-15T08:06:32Z
publishDate	2006
publisher	The Japanese Society of Environmental Toxicology
recordtype	eprints
repository_type	Digital Repository
spelling	upm-162372015-09-28T08:46:40Z http://psasir.upm.edu.my/id/eprint/16237/ Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus. Koyama, Jiro Imai, Shoko Fujii, Kazunori Kawai , Shin-ichiro Yap, Chee Kong Ismail, Ahmad Estrogens (17 B-estradiol and estrone) concentrations in river and estuarine waters around Kuala Lumpur, Malaysia were determined by enzyme-linked immunosorbent assay while estrogenic potential of the waters were ascertained by three in vitro bioassays, namely E-screen, Ishikawa cell-alkaline phosphatase and yeast estrogen screen. Moreover, hepatic vitellogenin, a precursor of yolk protein that is specific to females, were examined in male and female Java-medaka collected in the same area. 17B-estradiol and estrone concentrations were less than 6.1 ng/L and 127 ng/L, respectively. The highest 17B-estradiol equivalent activity, 284 ng/L, was detected by in vitro assay in Sungai Kuyoh, which was adjacent to a sewage plant. 17B-estradiol and estrone concentrations were not equal to their estrogenic potentials determined by in vitro assay implying the presence of other estrogenic chemicals in these waters. Hepatic vitellogenin concentrations of both male and female java-medaka were the same to laboratory-cultured individuals. Although relatively high estrogen concentrations were detected in some waters of Malaysia, these were not high enough to induce hepatic vitellogenin in male fishes. Further research, however, is necessary to cover more number of sampling sites. The Japanese Society of Environmental Toxicology 2006 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16237/1/Pollution%20by%20estrogens%20in%20river%20and%20estuarine%20waters%20around%20Kuala%20Lumpur.pdf Koyama, Jiro and Imai, Shoko and Fujii, Kazunori and Kawai , Shin-ichiro and Yap, Chee Kong and Ismail, Ahmad (2006) Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus. Japanese Journal of Environmental Toxicology, 9 (2). pp. 141-147. ISSN 1882-5958 http://www.intio.or.jp/jset/ http://dx.doi.org/10.11403/jset.9.141 English
spellingShingle	Koyama, Jiro Imai, Shoko Fujii, Kazunori Kawai , Shin-ichiro Yap, Chee Kong Ismail, Ahmad Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title	Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title_full	Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title_fullStr	Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title_full_unstemmed	Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title_short	Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.
title_sort	pollution by estrogens in river and estuarine waters around kuala lumpur, malaysia, and their effects on the estuarine java-medaka, oryzias javanicus.
url	http://psasir.upm.edu.my/id/eprint/16237/ http://psasir.upm.edu.my/id/eprint/16237/ http://psasir.upm.edu.my/id/eprint/16237/ http://psasir.upm.edu.my/id/eprint/16237/1/Pollution%20by%20estrogens%20in%20river%20and%20estuarine%20waters%20around%20Kuala%20Lumpur.pdf

Pollution by estrogens in river and estuarine waters around Kuala Lumpur, Malaysia, and their effects on the estuarine Java-medaka, Oryzias javanicus.

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