Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure
Phyllanthus niruri is commonly used for treatment of jaundice, hepatitis, kidney stones, diuretics, influenza and antibacterial agent. This study was conducted to investigate the effects of P. niruri in reducing the severity of azotaemia in rats induced with chronic renal damage. A total of 32 male...
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| Format: | Article |
| Language: | English |
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Malaysian Medical Association
2010
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| Online Access: | http://psasir.upm.edu.my/id/eprint/16189/ http://psasir.upm.edu.my/id/eprint/16189/1/Phyllanthus%20niruri%20reduces%20renal%20azotaemia%20in%20rats%20induced%20with%20chronic%20renal%20failure.pdf |
| _version_ | 1848842890182131712 |
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| author | Hamzah, Hazilawati P., Farah Dina Shaari, Mohd Rosly Sithambaram, Shanmugavelu Mohamed Mustapha, Noordin |
| author_facet | Hamzah, Hazilawati P., Farah Dina Shaari, Mohd Rosly Sithambaram, Shanmugavelu Mohamed Mustapha, Noordin |
| author_sort | Hamzah, Hazilawati |
| building | UPM Institutional Repository |
| collection | Online Access |
| description | Phyllanthus niruri is commonly used for treatment of jaundice, hepatitis, kidney stones, diuretics, influenza and antibacterial agent. This study was conducted to investigate the effects of P. niruri in reducing the severity of azotaemia in rats induced with chronic renal damage. A total of 32 male Sprague Dawley rats were randomly assigned into four treatment groups; Group A (control), Group B (adenine), Group C (P. niruri) and Group D (adenine+P. niruri), consisting of 8 rats each. Chronic renal damage was induced using 0.75% adenine mixed with rat diet (daily feeding for 6 weeks). P. niruri was supplemented daily at a dose of 3000 mg/kg body weight throughout the 10 weeks of the experimental period. Results showed that P. niruri reduced the severity of azotaemia in rats induced with chronic renal damage. |
| first_indexed | 2025-11-15T08:06:19Z |
| format | Article |
| id | upm-16189 |
| institution | Universiti Putra Malaysia |
| institution_category | Local University |
| language | English |
| last_indexed | 2025-11-15T08:06:19Z |
| publishDate | 2010 |
| publisher | Malaysian Medical Association |
| recordtype | eprints |
| repository_type | Digital Repository |
| spelling | upm-161892016-11-21T08:52:09Z http://psasir.upm.edu.my/id/eprint/16189/ Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure Hamzah, Hazilawati P., Farah Dina Shaari, Mohd Rosly Sithambaram, Shanmugavelu Mohamed Mustapha, Noordin Phyllanthus niruri is commonly used for treatment of jaundice, hepatitis, kidney stones, diuretics, influenza and antibacterial agent. This study was conducted to investigate the effects of P. niruri in reducing the severity of azotaemia in rats induced with chronic renal damage. A total of 32 male Sprague Dawley rats were randomly assigned into four treatment groups; Group A (control), Group B (adenine), Group C (P. niruri) and Group D (adenine+P. niruri), consisting of 8 rats each. Chronic renal damage was induced using 0.75% adenine mixed with rat diet (daily feeding for 6 weeks). P. niruri was supplemented daily at a dose of 3000 mg/kg body weight throughout the 10 weeks of the experimental period. Results showed that P. niruri reduced the severity of azotaemia in rats induced with chronic renal damage. Malaysian Medical Association 2010 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/16189/1/Phyllanthus%20niruri%20reduces%20renal%20azotaemia%20in%20rats%20induced%20with%20chronic%20renal%20failure.pdf Hamzah, Hazilawati and P., Farah Dina and Shaari, Mohd Rosly and Sithambaram, Shanmugavelu and Mohamed Mustapha, Noordin (2010) Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure. Medical Journal of Malaysia, 65 (suppl.B). pp. 132-134. ISSN 0300-5283 http://www.e-mjm.org/2010/Sup_tissue_engineering_content.pdf |
| spellingShingle | Hamzah, Hazilawati P., Farah Dina Shaari, Mohd Rosly Sithambaram, Shanmugavelu Mohamed Mustapha, Noordin Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title | Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title_full | Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title_fullStr | Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title_full_unstemmed | Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title_short | Phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| title_sort | phyllanthus niruri reduces renal azotaemia in rats induced with chronic renal failure |
| url | http://psasir.upm.edu.my/id/eprint/16189/ http://psasir.upm.edu.my/id/eprint/16189/ http://psasir.upm.edu.my/id/eprint/16189/1/Phyllanthus%20niruri%20reduces%20renal%20azotaemia%20in%20rats%20induced%20with%20chronic%20renal%20failure.pdf |