Defects in nerve conduction velocity and different muscle fibre-type specificity contribute to muscle weakness in Ts1Cje Down syndrome mouse model
Background: Down syndrome (DS) is a genetic disorder caused by presence of extra copy of human chromosome 21. It is characterised by several clinical phenotypes. Motor dysfunction due to hypotonia is commonly seen in individuals with DS and its etiology is yet unknown. Ts1Cje, which has a partial tr...
| Main Authors: | Bala, Usman, Leong, Melody Pui Yee, Lim, Chai Ling, Kadir @ Shahar, Hayati, Othman, Fauziah, Lai, Mei I., Law, Zhe Kang, Ramli, Khairunnisa, Htwe, Ohnmar, Ling, King Hwa, Cheah, Pike See |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science
2018
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/15954/ http://psasir.upm.edu.my/id/eprint/15954/1/15954.pdf |
Similar Items
Perturbed metabolic profiles associated with muscle weakness seen in adult Ts1Cje mouse model of Down syndrome
by: Lim, Chai Ling, et al.
Published: (2019)
by: Lim, Chai Ling, et al.
Published: (2019)
Targeted differential gene expression profiling of skeletal muscles isolated from Ts1Cje mouse model for Down syndrome
by: Leong, Melody Pui Yee, et al.
Published: (2015)
by: Leong, Melody Pui Yee, et al.
Published: (2015)
Expression profiling of genes involved in the development and function of skeletal muscles in Ts1Cje mouse model of down syndrome
by: Cheah, Pike See, et al.
Published: (2018)
by: Cheah, Pike See, et al.
Published: (2018)
Transcriptomic and protein expression analyses of skeletal muscles isolated from Ts1cje mouse model for Down syndrome
by: Leong, Melody Pui Yee
Published: (2017)
by: Leong, Melody Pui Yee
Published: (2017)
Ts1Cje mouse model for Down syndrome research
by: Ling, King Hwa
Published: (2015)
by: Ling, King Hwa
Published: (2015)
Metabolic and functional characterisation of adult skeletal muscle in down syndrome mouse model (Ts1CJe) for insights into hypotonia in human condition
by: Lim, Chai Ling
Published: (2017)
by: Lim, Chai Ling
Published: (2017)
The role of JAK-STAT signalling in the developing brain of Ts1Cje mouse model for Down syndrome
by: Lee, Han Chung, et al.
Published: (2015)
by: Lee, Han Chung, et al.
Published: (2015)
Transcriptional profiling of the postnatal brain of the Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2014)
by: Tan, Kai Leng, et al.
Published: (2014)
Ts1Cje mouse model for Down syndrome exhibits motor function deficit; the potential role of MRFS and peripheral nervous system
by: Bala, Usman, et al.
Published: (2015)
by: Bala, Usman, et al.
Published: (2015)
Histological and molecular characterisation of hypotonia in adult Ts1Cje mouse model for down syndrome
by: Bala, Usman
Published: (2016)
by: Bala, Usman
Published: (2016)
The expression profile of miR-3099 during neural development of Ts1Cje mouse model of down syndrome
by: Zainal Abidin, Shahidee, et al.
Published: (2021)
by: Zainal Abidin, Shahidee, et al.
Published: (2021)
Overexpression of interferon alpha or beta receptors in the brain of adult Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2015)
by: Tan, Kai Leng, et al.
Published: (2015)
Gene and protein expression profiles of JAK-STAT signalling pathway in the developing brain of the Ts1Cje down syndrome mouse model
by: Lee, Han Chung, et al.
Published: (2019)
by: Lee, Han Chung, et al.
Published: (2019)
Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
by: Hewitt, Chelsee Ann, et al.
Published: (2010)
by: Hewitt, Chelsee Ann, et al.
Published: (2010)
Expression profiling of notch signalling pathway and gamma-secretase activity in the brain of Ts1Cje mouse model of down syndrome
by: Md Yusof, Hadri Hadi, et al.
Published: (2019)
by: Md Yusof, Hadri Hadi, et al.
Published: (2019)
Disrupted interferon-related molecular networks and the over-expressed Ifnar1 in the brain of adult Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2016)
by: Tan, Kai Leng, et al.
Published: (2016)
Expression of gamma secretase and notch signalling pathway in TS1CJE mouse model of down syndrome
by: Md Yusof, Hadri Hadi
Published: (2017)
by: Md Yusof, Hadri Hadi
Published: (2017)
Reduced REST expression in neural progenitor cells, adult cortex, and impaired REST nuclear translocation in the prefrontal cortex of Ts1Cje mouse model of Down Syndrome
by: Chong, Teik Lim, et al.
Published: (2024)
by: Chong, Teik Lim, et al.
Published: (2024)
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
by: Ling, King Hwa, et al.
Published: (2014)
by: Ling, King Hwa, et al.
Published: (2014)
The identification of disrupted molecular networks involved in brain maturation and function in the Ts1Cje mouse model of down syndrome.
by: Cheah, P. S.
by: Cheah, P. S.
Identification of disrupted molecular networks involved in brain maturation and function in the TS1CJE mouse model of down syndrome
by: Tan, Kai Leng
Published: (2016)
by: Tan, Kai Leng
Published: (2016)
Metabolic profiling of neurospheres derived from embryonic cerebral cortex Ts1Cje mouse model for down syndrome
by: Mohamed Seth, Eryse Amira
Published: (2019)
by: Mohamed Seth, Eryse Amira
Published: (2019)
Olfactory ensheathing cells seeded muscle-stuffed vein as nerve conduit for peripheral nerve repair: a nerve conduction study
by: Lokanathan, Yogeswaran, et al.
Published: (2014)
by: Lokanathan, Yogeswaran, et al.
Published: (2014)
Neural-differentiated mesenchymal stem cells incorporated into muscle stuffed vein scaffold forms a stable living nerve conduit
by: Hassan, Nur Hidayah, et al.
Published: (2012)
by: Hassan, Nur Hidayah, et al.
Published: (2012)
Human muscle weakness and fatigue: the effects of disuse, age and exercise
by: White, Michael J.
Published: (1987)
by: White, Michael J.
Published: (1987)
The roles of muscle contraction and pharmaceuticals on
restoring glucose uptake in a mouse skeletal muscle
model of immobilization
by: Kirkpatrick, Euan
Published: (2024)
by: Kirkpatrick, Euan
Published: (2024)
Mouse mitochondrial lipid composition is defined by age in brain and muscle
by: Pollard, Amelia K., et al.
Published: (2017)
by: Pollard, Amelia K., et al.
Published: (2017)
Additional muscle in the popliteal fossa – a potential source of entrapment of tibial nerve.
by: Surekha, DS, et al.
Published: (2013)
by: Surekha, DS, et al.
Published: (2013)
Additional Innervations of Pectoral Muscles by the Intercostobrachial Nerve Associated With Duplication of Medial and Lateral Pectoral Nerves – A Case Report
by: Shetty P.,, et al.
Published: (2015)
by: Shetty P.,, et al.
Published: (2015)
Entrapment of Brachial Artery and Median Nerve within the Brachialis Muscle – A Case Report
by: Vasanthakumar P.,, et al.
Published: (2015)
by: Vasanthakumar P.,, et al.
Published: (2015)
Harvesting the maximum length of sciatic nerve from adult mice: a step-by-step approach
by: Bala, Usman, et al.
Published: (2014)
by: Bala, Usman, et al.
Published: (2014)
Effect of tocotrienol rich fraction (TRF) on muscles reinnervation after sciatic nerve crush injury in rats
by: Lailanor, Amalia, et al.
Published: (2020)
by: Lailanor, Amalia, et al.
Published: (2020)
Prenatal ruxolitinib treatment improved muscle strength but showed no impact on the neurobehavioral and electrophysiological traits in adult mice
by: Azimzadeh, Mansour, et al.
Published: (2024)
by: Azimzadeh, Mansour, et al.
Published: (2024)
Heavy metals in Shrimp pond and Shrimp muscles
by: Ling, T. Y., et al.
Published: (2007)
by: Ling, T. Y., et al.
Published: (2007)
Endotoxin induced muscle wasting in avian and murine skeletal muscle
by: Tarabees, Reda Zakaria Ibrahim
Published: (2011)
by: Tarabees, Reda Zakaria Ibrahim
Published: (2011)
Gluteus Medius Muscle Activation During Isometric Muscle Contractions
by: O'Dwyer, C., et al.
Published: (2011)
by: O'Dwyer, C., et al.
Published: (2011)
Porous plga sheet and acellularized muscle stuffed vein seeded with neural- differentiated mscs are potential scaffolds for nerve regeneration
by: NH, Hidayah, et al.
Published: (2012)
by: NH, Hidayah, et al.
Published: (2012)
Schwann cell-axon metabolic interactions of the mouse sciatic nerve
by: Rich, Laura
Published: (2017)
by: Rich, Laura
Published: (2017)
Glutamine and skeletal muscle
by: Tirapegui, J., et al.
Published: (2015)
by: Tirapegui, J., et al.
Published: (2015)
The age-related loss of skeletal muscle mass and function: measurement and physiology of muscle fibre atrophy and muscle fibre loss in humans
by: Wilkinson, Daniel J., et al.
Published: (2018)
by: Wilkinson, Daniel J., et al.
Published: (2018)
Similar Items
-
Perturbed metabolic profiles associated with muscle weakness seen in adult Ts1Cje mouse model of Down syndrome
by: Lim, Chai Ling, et al.
Published: (2019) -
Targeted differential gene expression profiling of skeletal muscles isolated from Ts1Cje mouse model for Down syndrome
by: Leong, Melody Pui Yee, et al.
Published: (2015) -
Expression profiling of genes involved in the development and function of skeletal muscles in Ts1Cje mouse model of down syndrome
by: Cheah, Pike See, et al.
Published: (2018) -
Transcriptomic and protein expression analyses of skeletal muscles isolated from Ts1cje mouse model for Down syndrome
by: Leong, Melody Pui Yee
Published: (2017) -
Ts1Cje mouse model for Down syndrome research
by: Ling, King Hwa
Published: (2015)