Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography.

QR Code

Mutational analysis of CYP2C8 in hypertensive patients using denaturing high performance liquid chromatography.

What is known and Objective: CYP2C8 is involved in the cytochrome P450 (CYP) epoxygenase pathway. Arachidonic acid metabolites such as epoxyeicosatrienenoic acids and hydroxyeicosatetrenoic acids, produced may have a role in hypertension. We aimed to develop a medium through-put method for screeni...

Full description

Bibliographic Details
Main Authors:	Teh, Lay Kek, Zahri, Mohd. Khiari, Zakaria, Zainul Amiruddin, Ismail, Rusli, Salleh, Mohd. Zaki
Format:	Article
Language:	English English
Published:	Blackwell Publishing Ltd. 2010
Online Access:	http://psasir.upm.edu.my/id/eprint/15767/ http://psasir.upm.edu.my/id/eprint/15767/1/Mutational%20analysis%20of%20CYP2C8%20in%20hypertensive%20patients%20using%20denaturing%20high%20performance%20liquid%20chromatography.pdf

Similar Items

Single nucleotide polymorphism (SNPS) analysis of Mu-opioid receptors (OPRM1) using denaturing high performance liquid chromatography (DHPLC) among the intravenous drug users
by: Teh, Lay Kek, et al.
Published: (2014)

Mutation detection of BRCA1 gene from Malaysian breast cancer patients by denaturing high performance liquid chromatography (DHPLC)
by: Mohamad Salih, Falah A., et al.
Published: (2009)

Genetic polymorphism of CYP2C9 in patients on warfarin therapy and the clinical relevance / Teh Lay Kek... [et al.]
by: Teh, Lay Kek, et al.
Published: (2007)

Electrochemical behaviour of denatured haemoglobin at the liquid|liquid interface
by: Herzog, G., et al.
Published: (2010)

CYP2C9 polymorphism: prevalence in healthy and warfarin-treated Malay and Chinese in Malaysia
by: Ngow, Harris Abdullah, et al.
Published: (2009)

Population Pharmacokinetics Of Repaglinide In Healthy Subjects And Genetic Polymorphisms Of Cyp3a4 And Cyp2c8
by: Abu Bakar, Ruzilawati
Published: (2008)

Genetic polymorphisms of cyp3a4 and cyp2c8 in heal thy volunteers administered with repaglinide
by: Gan Siew, Hua
Published: (2008)

Genetic polymorphisms of CYP 3A4 & CYP2C8 in healthy volunteers title of project administered with repaglinide
by: Hua, Gan Siew
Published: (2008)

Lack of correlation between INR and warfarin dose: a role of pharmacogenotyping of CYP2C9*3 and VKORC1 for anticoagulation
by: Salleh, Mohd Zaki, et al.
Published: (2009)

The role of pharmacogenetic variation in metoprolol CYP2D6 genotypes polymorphism
by: Wan Sulaiman, Wan Mohd. Azizi, et al.
Published: (2011)

Pharmacogenotyping of CYP3A5 in predicting dose-adjusted trough levels of tacrolimus among Malaysian kidney-transplant patients
by: Hamzah, Sharina, et al.
Published: (2014)

Tacrolimus pharmacogenetics: the influence of genetic polymorphisms of CYP3A5, MDRl and Pregnane X Receptor (PXR) in transplant patients / Professor Dr. Mohd Zaki Salleh and Associate Prof. Dr Teh Lay Kek
by: Salleh, Mohd Zaki, et al.
Published: (2010)

Role of pharmacodiagnostic of CYP2C9 variants in the optimization of warfarin therapy in Malaysia: a 6-month follow-up study
by: Ngow, Harris Abdullah, et al.
Published: (2008)

Involvement of CYP450 system in hepatoprotective activity of Malaysian Agricultural Research and Development Institute (MARDI)-produced virgin coconut oils.
by: Zakaria, Zainul Amiruddin, et al.
Published: (2011)

Protein denaturation in pilot scale spray dryer
by: Kioh, Shin Fang
Published: (2010)

Denaturation behavior and conformational states of champedak galactose-binding lectin under various denaturing conditions / Nurul Iman Ahamed Kameel
by: Nurul Iman , Ahamed Kameel
Published: (2018)

Thermal Denaturation Kinetics of Whey Protein and Maltodextrin Mixture
by: Nuraini, Mohd Yusoff, et al.
Published: (2013)

Analytical quantification method of protein denaturation in spray drying
by: Suria, Mahmud
Published: (2012)

Mutations Of Pro30Leu And Val281Leu Of The Cyp21 Gene In Patients Diagnosed With Ambiguous Genitalia.
by: Isa, M.N., et al.
Published: (2002)

Liquid Chromatography-Mass Spectrometry
by: Busetti, Francesco, et al.
Published: (2013)

Liquid and Thin-Layer Chromatography
by: Lewis, Simon, et al.
Published: (2013)

Effects of Thermal Denaturation on the Solid-State Structure and Molecular Mobility of Glycinin
by: Huson, M., et al.
Published: (2011)

Calcium-induced stabilization of α-amylase against guanidine hydrochloride denaturation
by: Tan, Cheau Yuaan, et al.
Published: (2010)

Analysis of Biogenic Amines in fish by using High Performance Liquid Chromatography
by: Nur Idatul Diana, bt Ahmad Zaki
Published: (2015)

Evaluation of mutation effects on UGT1A1 activity toward 17beta-estradiol using liquid chromatography-tandem mass spectrometry
by: Wada, Keiko, et al.
Published: (2006)

Genetic variation of Pyrenophora teres f. teres isolates in Western Australia and emergence of a Cyp51A fungicide resistance mutation
by: Ellwood, Simon, et al.
Published: (2018)

Development Of Denaturing High Performance Liquid Chromatography (Dhplc) In Detection Of Common Polymorphisms In The Multi-Drug Resistance (MDR1) Gene Among Malay Patients With Leukemia [QH324.9.L5 B138 2006 f rb].
by: Yahaya, Badrul Hisham
Published: (2006)

Detection of Gelatin Origin Using Fourier Transform Infrared Spectroscopy and High Performance Liquid Chromatography
by: Rusli, Norakasha
Published: (2011)

Clinical relevance of VKORC1 (G-1639A and C1173T) and CYP2C9*3 among patients on warfarin
by: Teh, L. K., et al.
Published: (2011)

Comparison of vitamin C content in citrus fruits by titration and high performance liquid chromatography (HPLC) methods
by: Ramli, Fatin Najwa, et al.
Published: (2017)

A partial length cyclophilin-encoding (cyp) cDNA isolated from Ganoderma boninense
by: Lim, Fook Hwa, et al.
Published: (2011)

Hepatoprotective and antioxidant activities of Dicranopteris linearis leaf extract against paracetamol-induced liver intoxication in rats
by: Zakaria, Zainul Amiruddin, et al.
Published: (2020)

Detection of o-nitrophenol in water samples by using high performance liquid chromatography (hplc) / Iffah Syazana Rusli
by: Rusli, Iffah Syazana
Published: (2017)

High temperature liquid chromatography and pressurized liquid extraction of polycyclic aromatic hydrocarbons
by: Md. Saleh, Noorashikin
Published: (2007)

A review on CYP11A1, CYP17A1, and CYP19A1 polymorphism studies: candidate susceptibility genes for polycystic ovary syndrome (PCOS) and infertility
by: Heidarzadehpilehrood, Roozbeh, et al.
Published: (2022)

Detection Of Point Mutation (Pro30Leu) In Exon 1 Of The 21-Hydroxylase Gene(Cyp21) In Patient With Congenital Adrenal Hyperplasia Using Digoxygenin System .
by: Muhamad, Y.K., et al.
Published: (2001)

Influence of extrinsic factors on guanidine hydrochloride denaturation of Bacillus licheniformis α-amylase / Salanee Kandandapani
by: Salanee , Kandandapani
Published: (2016)

In vitro study of modulatory effects of Strobilanthes crispus extracts on human cDNA-expressed cytochrome P450 2A6 (CYP2A6) and CYP3A4
by: pan, Yan, et al.
Published: (2016)

δ13C analysis of bulk organic matter in speleothems using liquid chromatography-isotope ratio mass spectrometry
by: Blyth, Alison, et al.
Published: (2013)

Mitochondrial DNA mutations in Malaysian female breast cancer patients
by: Omasanggar, Raevathi, et al.
Published: (2020)