Mitogen-activated protein/extracellular signal-regulated kinase kinase 1act/tubulin interaction is an important determinant of mitotic stability in cultured HT1080 human fibrosarcoma cells.
Activation of the mitogen-activated protein kinase (MAPK) pathway plays a major role in neoplastic cell transformation. Using a proteomics approach, we identified alpha tubulin and beta tubulin as proteins that interact with activated MAP/extracellular signal-regulated kinase kinase 1 (MEK1), a cent...
| Main Authors: | Cao, Jia-ning, Shafee, Norazizah, Vickery, Larry, Kaluz, Stefan, Ru, Ning, Stanbridge, Eric J. |
|---|---|
| Format: | Article |
| Language: | English English |
| Published: |
American Association for Cancer Research
2010
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| Subjects: | |
| Online Access: | http://psasir.upm.edu.my/id/eprint/15646/ http://psasir.upm.edu.my/id/eprint/15646/1/Mitogen.pdf |
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