The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings

Medial coronoid disease (MCD) encompasses lesions of the entire medial coronoid process (MCP), both of the articular cartilage and the subchondral bone. To detect the earliest signs of MCD, radiography and computed tomography were used to monitor the development of MCD in 14 Labrador retrievers, fro...

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Main Authors: Lau, Seng Fong, Wolschrijn, Claudia F., Hazewinkel, Herman Anthonie Willem, Siebelt, Michiel, Voorhout, George
Format: Article
Language:English
Published: Elsevier 2013
Online Access:http://psasir.upm.edu.my/id/eprint/15255/
http://psasir.upm.edu.my/id/eprint/15255/1/The%20early%20development%20of%20medial%20coronoid%20disease%20in%20growing%20Labrador%20retrievers%20radiographic%2C%20computed%20tomographic%2C%20necropsy%20and%20micro-computed%20tomographic%20findings.pdf
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author Lau, Seng Fong
Wolschrijn, Claudia F.
Hazewinkel, Herman Anthonie Willem
Siebelt, Michiel
Voorhout, George
author_facet Lau, Seng Fong
Wolschrijn, Claudia F.
Hazewinkel, Herman Anthonie Willem
Siebelt, Michiel
Voorhout, George
author_sort Lau, Seng Fong
building UPM Institutional Repository
collection Online Access
description Medial coronoid disease (MCD) encompasses lesions of the entire medial coronoid process (MCP), both of the articular cartilage and the subchondral bone. To detect the earliest signs of MCD, radiography and computed tomography were used to monitor the development of MCD in 14 Labrador retrievers, from 6 to 7 weeks of age until euthanasia. The definitive diagnosis of MCD was based on necropsy and micro-computed tomography findings. The frequency of MCD in the dogs studied was 50%. Radiographic findings did not provide evidence of MCD, ulnar subtrochlear sclerosis or blunting of the cranial edge of the MCP. Computed tomography was more sensitive (30.8%) than radiography (0%) in detecting early MCD, with the earliest signs detectable at 14 weeks of age. A combination of the necropsy and micro-computed tomography findings of the MCP showed that MCD was manifested as a lesion of only the subchondral bone in dogs <18 weeks of age. In all dogs (affected and unaffected), there was close contact between the base of the MCP and the proximal radial head in the congruent joints. Computed tomography and micro-computed tomography findings indicated that the lesions of MCD probably originated at the base of the MCP.
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spelling upm-152552019-05-09T01:28:09Z http://psasir.upm.edu.my/id/eprint/15255/ The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings Lau, Seng Fong Wolschrijn, Claudia F. Hazewinkel, Herman Anthonie Willem Siebelt, Michiel Voorhout, George Medial coronoid disease (MCD) encompasses lesions of the entire medial coronoid process (MCP), both of the articular cartilage and the subchondral bone. To detect the earliest signs of MCD, radiography and computed tomography were used to monitor the development of MCD in 14 Labrador retrievers, from 6 to 7 weeks of age until euthanasia. The definitive diagnosis of MCD was based on necropsy and micro-computed tomography findings. The frequency of MCD in the dogs studied was 50%. Radiographic findings did not provide evidence of MCD, ulnar subtrochlear sclerosis or blunting of the cranial edge of the MCP. Computed tomography was more sensitive (30.8%) than radiography (0%) in detecting early MCD, with the earliest signs detectable at 14 weeks of age. A combination of the necropsy and micro-computed tomography findings of the MCP showed that MCD was manifested as a lesion of only the subchondral bone in dogs <18 weeks of age. In all dogs (affected and unaffected), there was close contact between the base of the MCP and the proximal radial head in the congruent joints. Computed tomography and micro-computed tomography findings indicated that the lesions of MCD probably originated at the base of the MCP. Elsevier 2013 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/15255/1/The%20early%20development%20of%20medial%20coronoid%20disease%20in%20growing%20Labrador%20retrievers%20radiographic%2C%20computed%20tomographic%2C%20necropsy%20and%20micro-computed%20tomographic%20findings.pdf Lau, Seng Fong and Wolschrijn, Claudia F. and Hazewinkel, Herman Anthonie Willem and Siebelt, Michiel and Voorhout, George (2013) The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings. The Veterinary Journal, 197 (3). pp. 724-730. ISSN 1090-0233; ESSN: 1532-2971 https://www.sciencedirect.com/science/article/pii/S1090023313001731#! 10.1016/j.tvjl.2013.04.002
spellingShingle Lau, Seng Fong
Wolschrijn, Claudia F.
Hazewinkel, Herman Anthonie Willem
Siebelt, Michiel
Voorhout, George
The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title_full The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title_fullStr The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title_full_unstemmed The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title_short The early development of medial coronoid disease in growing Labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
title_sort early development of medial coronoid disease in growing labrador retrievers: radiographic, computed tomographic, necropsy and micro-computed tomographic findings
url http://psasir.upm.edu.my/id/eprint/15255/
http://psasir.upm.edu.my/id/eprint/15255/
http://psasir.upm.edu.my/id/eprint/15255/
http://psasir.upm.edu.my/id/eprint/15255/1/The%20early%20development%20of%20medial%20coronoid%20disease%20in%20growing%20Labrador%20retrievers%20radiographic%2C%20computed%20tomographic%2C%20necropsy%20and%20micro-computed%20tomographic%20findings.pdf